anti-Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) Antikörper

Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Zusätzlich bieten wir Ihnen USP7 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
USP7 252870 Q6A4J8
USP7 7874 Q93009
USP7 360471 Q4VSI4
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Top anti-USP7 Antikörper auf antikoerper-online.de

Showing 10 out of 210 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rat Target Name: USP7 Sample Tissue: Rat Brain Antibody Dilution: 1ug/ml WB Suggested Anti-USP7 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: A549 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IP, IHC, PLA, WB Western Blot: USP7 Antibody [ABIN151954] - Detection of Human and Mouse USP7 by Western Blot (h and m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 ug) and mouse NIH3T3 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-USP7 antibody ABIN151954 (lot ABIN151954-3) used for WB at 0.1 ug/ml (A) and 1 ug/ml (B) and used for IP at 3 ug/mg lysate. USP7 was also immunoprecipitated by a previous lot (lot ABIN151954-2) of this antibody. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 1 second (B). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert EIA, WB USP7 Antibody (Center) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the USP7 antibody detected the USP7 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Schimpanse Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$411.18
Details
Human Maus Unkonjugiert ELISA, WB Figure 1: Western blot analysis using HAUSP mouse mAb against MCF-7 (1) cell lysate. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$393.80
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Huhn Kaninchen Unkonjugiert IHC (p), WB Anti-USP7 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960399 concentration 10 ug/ml. Anti-USP7 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960399 concentration 10 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Human Maus Unkonjugiert FACS, IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Human Maus Unkonjugiert IHC (p), WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details

USP7 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-USP7 Antikörper

  1. Human Polyclonal USP7 Primary Antibody für ICC, IF - ABIN151954 : Canning, Boutell, Parkinson, Everett: A RING finger ubiquitin ligase is protected from autocatalyzed ubiquitination and degradation by binding to ubiquitin-specific protease USP7. in The Journal of biological chemistry 2004 (PubMed)
    Show all 25 Pubmed References

  2. Human Monoclonal USP7 Primary Antibody für ELISA, WB - ABIN966249 : Abély: [Treatment of airway inflammation in cystic fibrosis]. in Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 2007 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal USP7 Primary Antibody für ELISA, WB - ABIN969186 : Becker, Marchenko, Maurice, Moll: Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma. in Cell death and differentiation 2007 (PubMed)
    Show all 3 Pubmed References

  4. Human Monoclonal USP7 Primary Antibody für EIA, WB - ABIN1109455 : Lu, Ma, Nguyen, Jones, Oren, Donehower: The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop. in Cancer cell 2007 (PubMed)
    Show all 3 Pubmed References

  5. Cow (Bovine) Polyclonal USP7 Primary Antibody für WB - ABIN2787924 : Nie, Zhang, Dai, Zhang, Zhao, Xu, Chen, Wang, Wang, Qiao: Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. in Biology of reproduction 2016 (PubMed)

Weitere Antikörper gegen USP7 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) Interaktionspartner

  1. reveal a conserved mechanism by which Ci/Gli (zeige GLI1 Antikörper) is stabilized by a deubiquitination enzyme and identify Usp7/HUASP as a critical regulator of Hh signaling and potential therapeutic target for Hh-related cancers

  2. Genetic and gene expression analyses suggested that GMPS (zeige GMPS Antikörper)/USP7 acts as a transcriptional corepressor

  3. GMP synthetase (zeige GMPS Antikörper) stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

Mouse (Murine) Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) Interaktionspartner

  1. Pit1 (zeige POU1F1 Antikörper) deletion inhibited USP7/IRS1 (zeige IRS1 Antikörper) dissociation upon insulin (zeige INS Antikörper) stimulation.

  2. EPOP (E130012A19Rik) interacts with elongin B (zeige TCEB2 Antikörper), elongin C (zeige TCEB1 Antikörper), and USP7 to modulate the chromatin landscape.

  3. USP7 is overexpressed and regulates homologous recombination repair in chronic lymphocytic leukemia cells.

  4. Findings demonstrate a crucial role of HAUSP in regulating N-Myc (zeige MYCN Antikörper) function in neuroblastoma (zeige ARHGEF16 Antikörper) in vivo and suggest that HAUSP inhibition is a potential therapy for MYCN (zeige MYCN Antikörper)-amplified tumors.

  5. The present study identified USP7 and TDP-43 (zeige TARDBP Antikörper) as the regulators of CRY1 (zeige CRY1 Antikörper) and CRY2 (zeige CRY2 Antikörper), underscoring the significance of the stability control process of CRY (zeige CRY2 Antikörper) proteins for period determination in the mammalian circadian clockwork.

  6. demonstrate that genotoxic stress stimulates Cry1 (zeige CRY1 Antikörper) phosphorylation and its deubiquitination by Herpes virus associated ubiquitin-specific protease (Hausp, a.k.a Usp7), stabilizing Cry1 (zeige CRY1 Antikörper) and shifting circadian clock time

  7. Our results demonstrate that the SCML2 (zeige SCML2 Antikörper)/USP7 complex constitutes a novel molecular pathway in modulating the epigenetic state of sex chromosomes during male meiosis

  8. USP7-mediated mono-deubiquitination of FoxO1 (zeige FOXO1 Antikörper) results in suppression of FoxO1 (zeige FOXO1 Antikörper) transcriptional activity through decreased FoxO1 (zeige FOXO1 Antikörper) occupancy on the promoters of gluconeogenic genes.

  9. Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60 (zeige KAT5 Antikörper).

  10. The ubiquitination-deubiquitination cascade mediated by the TRIM27 (zeige RFP Antikörper)-USP7 complex plays an important role in TNF-alpha (zeige TNF Antikörper)-induced apoptosis.

Human Ubiquitin Specific Peptidase 7 (Herpes Virus-Associated) (USP7) Interaktionspartner

  1. the overexpression of USP7 might promote cell proliferation by deubiquitinating Ki-67 (zeige MKI67 Antikörper) protein

  2. these data identify DUB3 (zeige USP17L2 Antikörper) and USP7 as factors that regulate DNA replication by controlling Geminin protein (zeige GMNN Antikörper) stability, and suggest that USP7 may be involved in Geminin (zeige GMNN Antikörper) dysregulation during breast cancer progression.

  3. Molecular mechanisms of USP7 substrate recognition and C-terminal activation have been described.

  4. USP7 promotes breast carcinogenesis by stabilizing PHF8 (zeige PHF8 Antikörper) and upregulating cyclin A2 (zeige CCNA2 Antikörper). and the interaction between USP7 and PHF8 (zeige PHF8 Antikörper) is augmented during DNA damage.

  5. Data suggest that SIRT7 (zeige SIRT7 Antikörper) undergoes Lys (zeige LYZ Antikörper)-63 polyubiquitination, later removed by USP7 to repress enzymatic activity of SIRT7 (zeige SIRT7 Antikörper); USP7 and SIRT7 (zeige SIRT7 Antikörper) regulate gluconeogenesis via expression of glucose-6-phosphatase catalytic subunit (G6PC (zeige G6PC Antikörper)); SIRT7 (zeige SIRT7 Antikörper) targets G6PC (zeige G6PC Antikörper) promoter through ELK4 (zeige ELK4 Antikörper). (SIRT7 (zeige SIRT7 Antikörper) = sirtuin 7 (zeige SIRT7 Antikörper); USP7 = ubiquitin specific peptidase 7; G6PC (zeige G6PC Antikörper) = glucose-6-phosphatase catalytic subunit (zeige G6PC Antikörper); ELK4 (zeige ELK4 Antikörper) = transcription factor ELK4 (zeige ELK4 Antikörper))

  6. USP7 is overexpressed and regulates homologous recombination repair in chronic lymphocytic leukemia cells.

  7. Findings demonstrate a crucial role of HAUSP in regulating N-Myc (zeige MYCN Antikörper) function in neuroblastoma (zeige ARHGEF16 Antikörper) in vivo and suggest that HAUSP inhibition is a potential therapy for MYCN (zeige MYCN Antikörper)-amplified tumors.

  8. findings suggest that Usp7 is important for MB cell proliferation and metastasis by activating Shh (zeige SHH Antikörper) pathway, and is a putative therapeutic target for MBs (zeige PPP1R12A Antikörper)

  9. Data suggest that HIV-1 (human immunodeficiency virus type 1) Tat (zeige TAT Antikörper) gene product is stabilized by host cell deubiquitinase USP7, leading to enhanced viral production; HIV-1 in turn up-regulates the USP7 protein expression in human T-lymphocytes.

  10. modulatory role for Trip12 (zeige TRIP12 Antikörper) in the USP7-dependent DNA damage response

USP7 Antigen-Profil

Protein Überblick

Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, PTEN and DAXX. Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination and proteasomal degradation. Deubiquitinates p53/TP53 and MDM2 and strongly stabilizes p53/TP53 even in the presence of excess MDM2, and also induces p53/TP53-dependent cell growth repression and apoptosis. Deubiquitination of FOXO4 in presence of hydrogen peroxide is not dependent on p53/TP53 and inhibits FOXO4-induced transcriptional activity. In association with DAXX, is involved in the deubiquitination and translocation of PTEN from the nucleus to the cytoplasm, both processes that are counteracted by PML. Involved in cell proliferation during early embryonic development. Involved in transcription-coupled recruited to DNA damage sites following interaction with KIAA1530/UVSSA and promotes deubiquitination of ERCC6, preventing UV-induced degradation of ERCC6 (By similarity).

Genbezeichner und Symbole assoziert mit USP7

  • Ubiquitin-specific protease 7 (Usp7) Antikörper
  • ubiquitin carboxyl-terminal hydrolase 7 (LOC100201254) Antikörper
  • ubiquitin specific peptidase 7 (USP7) Antikörper
  • ubiquitin specific peptidase 7 (Usp7) Antikörper
  • 2210010O09Rik Antikörper
  • AA409944 Antikörper
  • AA617399 Antikörper
  • AU019296 Antikörper
  • AW548146 Antikörper
  • C80752 Antikörper
  • CG1490 Antikörper
  • Dmel\\CG1490 Antikörper
  • HAUSP Antikörper
  • TEF1 Antikörper
  • UBP Antikörper
  • USP7 Antikörper

Bezeichner auf Proteinebene für USP7

CG1490-PB , Usp7-PB , ubiquitin specific peptidase 7 (herpes virus-associated) , ubiquitin carboxyl-terminal hydrolase 7-like , deubiquitinating enzyme 7 , herpesvirus-associated ubiquitin-specific protease , mHAUSP , ubiquitin carboxyl-terminal hydrolase 7 , ubiquitin specific protease 7 , ubiquitin thioesterase 7 , ubiquitin thiolesterase 7 , ubiquitin-specific-processing protease 7 , Herpes virus-associated ubiquitin-specific protease , ubiquitin specific protease 7 (herpes virus-associated) , herpes-virus-associated ubiquitin-specific protease , rHAUSP , ubiquitin-specific peptidase 7

GENE ID SPEZIES
32169 Drosophila melanogaster
100201254 Hydra magnipapillata
100468835 Ailuropoda melanoleuca
252870 Mus musculus
7874 Homo sapiens
360471 Rattus norvegicus
395126 Gallus gallus
479854 Canis lupus familiaris
100190899 Sus scrofa
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