anti-Ubiquitin Conjugation Factor E4 B (UBE4B) Antikörper

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Zusätzlich bieten wir Ihnen UBE4B Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
UBE4B 298652  
UBE4B 10277 O95155
UBE4B 63958 Q9ES00
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Top anti-UBE4B Antikörper auf antikoerper-online.de

Showing 10 out of 49 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-UBE4B Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Human brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-UBE4B Pab (ABIN388841) is used in Western blot to detect UBE4B in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 5% SDS PAGE antibody diluted at 1:10000 IHC-P Image Immunohistochemical analysis of paraffin-embedded CA922 xenograft, using UBE4B, antibody at 1:500 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert IP, WB Western Blot and Immunoprecipitation: UBE4B Antibody [ABIN188793] - Detection of Human and Mouse UBE4B by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-UBE4B antibody ABIN188793 used for WB at 0.04 mcg/ml (A) and 0.1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. UBE4B was also immunoprecipitated by rabbit anti-UBE4B antibody ABIN188794, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 3 minutes (B). Western Blot: UBE4B Antibody  - Detection of Human UBE4B by Western Blot. Samples: Whole cell lysate (5, 15 and 50 ug) from HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-UBE4B antibody  used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$556.31
Details
Hund Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB   0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: UBE4B Antibody [NBP1-32737] - Paraffin-embedded CA922 xenograft, using antibody at 1:500 dilution. Immunocytochemistry/Immunofluorescence: UBE4B Antibody [NBP1-32737] - Analysis of methanol-fixed Hep3B, using antibody at 1:500 dilution. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.63 KDa) . 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert WB 0.1 mg Anmelden zum Anzeigen 3 bis 4 Tage
$601.76
Details

UBE4B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Rat (Rattus)


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Mouse (Murine)


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Am meisten referenzierte anti-UBE4B Antikörper

  1. Human Polyclonal UBE4B Primary Antibody für IHC, IHC (p) - ABIN4363967 : Arabi, Ullah, Branca, Johansson, Bandarra, Haneklaus, Fu, Ariës, Nilsson, Den Boer, Pokrovskaja, Grandér, Xiao, Rocha, Lehtiö, Sangfelt: Proteomic screen reveals Fbw7 as a modulator of the NF-κB pathway. in Nature communications 2012 (PubMed)

Weitere Antikörper gegen UBE4B Interaktionspartner

Human Ubiquitin Conjugation Factor E4 B (UBE4B) Interaktionspartner

  1. miR (zeige MLXIP Antikörper)-1301 functions as a tumor suppressor that inhibits tumor cell migration and invasion in multiple human cancer cells by regulating the UBE4B-p53 (zeige TP53 Antikörper) pathway.

  2. UBE4B promotes endogenous phospho-p53 (zeige TP53 Antikörper)(S15 (zeige FBLN3 Antikörper)) and phospho-p53 (zeige TP53 Antikörper)(S392) degradation in response to gamma irradiation. UBE4B plays an important role in regulating phosphorylated p53 (zeige TP53 Antikörper) following DNA damage.

  3. UBE4B overexpression promotes the oncogenic properties of HCC (zeige FAM126A Antikörper) and is correlated with an unfavorable prognosis in HCC (zeige FAM126A Antikörper) patients.

  4. UBE4B regulates p53 (zeige TP53 Antikörper) in breast cancer

  5. We propose a model in which the coordinated action of UBE4B, ESCRT-0, and the deubiquitinating enzyme USP8 (zeige USP8 Antikörper) enable the endosomal sorting and lysosomal degradation of the EGFR (zeige EGFR Antikörper).

  6. UBE4B-mediated growth factor receptor (zeige RYK Antikörper) trafficking may contribute to the poor prognosis of patients who have neuroblastoma (zeige ARHGEF16 Antikörper) tumors with 1p36 deletions.

  7. The regulated expression of these UFD2a isoforms most likely imparts divergent functions that are important for myogenesis.

  8. we found somatic mutations of HERC2 (zeige HERC2 Antikörper), HERC3 (zeige HERC3 Antikörper), TRIP12 (zeige TRIP12 Antikörper), UBE2Q1 (zeige UBE2Q1 Antikörper) and UBE4B genes in gastric carcinoma and colorectal carcinomas with microsatellite instability

  9. data indicate that amplification and overexpression of UBE4B represent previously undescribed molecular mechanisms of inactivation of p53 (zeige TP53 Antikörper) in brain tumors

  10. determined structures of E4B U box free and bound to UbcH5c (zeige UBE2D3 Antikörper) and Ubc4 (zeige UBE2D2 Antikörper) E2s; findings show E4B U box is a monomer stabilized by a network of hydrogen bonds; findings suggest allosteric regulation of UbcH5c (zeige UBE2D3 Antikörper) and Ubc4 (zeige UBE2D2 Antikörper) by E4B U box

Mouse (Murine) Ubiquitin Conjugation Factor E4 B (UBE4B) Interaktionspartner

  1. The regulated expression of these UFD2a isoforms most likely imparts divergent functions that are important for myogenesis.

  2. Characterization of the UFD2a gene.

  3. UFD2a is essential for the development of cardiac muscle, as well as for the protection of spinocerebellar neurons from degeneration induced by endoplasmic reticulum stress.

UBE4B Antigen-Profil

Protein Überblick

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit UBE4B

  • ubiquitination factor E4B (Ube4b) Antikörper
  • putative ubiquitin conjugation factor E4 B (LINJ_30_1070) Antikörper
  • putative ubiquitin conjugation factor E4 B (LBRM_30_1130) Antikörper
  • ubiquitin conjugation factor E4 B (Tsp_12732) Antikörper
  • ubiquitin conjugation factor E4 B (Tsp_01624) Antikörper
  • ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) (ube4b) Antikörper
  • ubiquitination factor E4B (UBE4B) Antikörper
  • 4930551I19Rik Antikörper
  • 4933406G05Rik Antikörper
  • AU014668 Antikörper
  • D4Bwg0973e Antikörper
  • E4 Antikörper
  • HDNB1 Antikörper
  • mKIAA0684 Antikörper
  • UBOX3 Antikörper
  • UFD2 Antikörper
  • UFD2a Antikörper
  • Ufd2p Antikörper

Bezeichner auf Proteinebene für UBE4B

ubiquitin conjugation factor E4 B , ubiquitination factor E4B (UFD2 homolog, yeast) , ubiquitination factor E4B, UFD2 homolog , ubiquitin fusion degradation protein 2 , UFD2A-III/UBE4B-III splice isoform , homologous to yeast UFD2 , homozygously deleted in neuroblastoma 1 , homozygously deleted in neuroblastoma-1 , ubiquitin-fusion degradation protein 2 , ubiquitination factor E4B (homologous to yeast UFD2)

GENE ID SPEZIES
298652 Rattus norvegicus
5070994 Leishmania infantum JPCM5
5417638 Leishmania braziliensis MHOM/BR/75/M2904
10899986 Trichinella spiralis
10911805 Trichinella spiralis
100380420 Salmo salar
10277 Homo sapiens
63958 Mus musculus
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