UBE4B Antikörper (C-Term)

Produktnummer ABIN2856674

Produktdetails anti-UBE4B Antikörper

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to UBE4B (ubiquitination factor E4B (UFD2 homolog, yeast))
UBE4B antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human UBE4B. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HepG2

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu UBE4B

Target: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Andere Bezeichnung: ubiquitination factor E4B (UBE4B Produkte)

Synonyme: ufd2a antikoerper, E4 antikoerper, HDNB1 antikoerper, UBOX3 antikoerper, UFD2 antikoerper, UFD2A antikoerper, 4930551I19Rik antikoerper, 4933406G05Rik antikoerper, AU014668 antikoerper, D4Bwg0973e antikoerper, UFD2a antikoerper, Ufd2p antikoerper, mKIAA0684 antikoerper, ubiquitination factor E4B antikoerper, putative ubiquitin conjugation factor E4 B antikoerper, ubiquitin conjugation factor E4 B antikoerper, ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) antikoerper, Ube4b antikoerper, LINJ_30_1070 antikoerper, LBRM_30_1130 antikoerper, Tsp_12732 antikoerper, Tsp_01624 antikoerper, ube4b antikoerper, UBE4B antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Cellular Localization: Cytoplasm

Molekulargewicht: 146 kDa

Gen-ID: 10277

UniProt: O95155