Trophoblast Glycoprotein Proteine (TPBG)

TPBG encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. Zusätzlich bieten wir Ihnen TPBG Antikörper (72) und TPBG Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
TPBG 7162 Q13641
TPBG 21983 Q9Z0L0
TPBG 83684 Q5PQV5
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Top TPBG Proteine auf antikoerper-online.de

Showing 8 out of 11 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$4,244.78
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$736.00
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$768.00
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
Details
Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,684.00
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,889.33
Details

TPBG Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , , ,
Mouse (Murine) ,
, ,
Rat (Rattus)

Weitere Proteine zu Trophoblast Glycoprotein (TPBG) Interaktionspartnern

Human Trophoblast Glycoprotein (TPBG) Interaktionspartner

  1. In conclusion, the present study provided evidence that TPBG is involved in PDAC metastasis, and that TPBG and its associated signaling pathways may be a suitable target for pancreatic ductal adenocarcinoma therapy.

  2. 5T4 expression is mechanistically associated with the directional movement of cells through epithelial mesenchymal transition, facilitation of CXCL12 (zeige CXCL12 Proteine)/CXCR4 (zeige CXCR4 Proteine) chemotaxis, blocking of canonical Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) while favouring non-canonical pathway signalling

  3. Tyrosine 325 plus the leucine-rich repeat 1 surface centered on a second exposed aromatic residue, phenylalanine 97, are essential for inhibition of Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signaling.

  4. The surface expression of 5T4 marks the use of the CXCR4 (zeige CXCR4 Proteine) rather than the CXCR7 (zeige CXCR7 Proteine) receptor, with distinct consequences for CXCL12 (zeige CXCL12 Proteine) exposure.

  5. 5T4 is a potential new antigen for targeted therapies such as immunotherapy in MPM, as it is overexpressed on mesothelioma cells and recognised by 5T4-specific cytotoxic T-cells.

  6. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen

  7. Results sugest that 5T4 is a transient marker of human embryonic stem cell differentiation & that 5T4 phenotype, colony seeding density and culture conditions influence the maintenance of pluripotent hES (zeige RRBP1 Proteine) cells and their differentiation to neural lineages.

  8. there is a repertoire of CD8 T cell recognition of 5T4 in normal human donors and some candidate HLA-A*0201 epitopes have been identified

  9. the mRNA expression of trophoblast glycoprotein is up-regulated in cells circulating within blood from women with preeclampsia.

  10. 5T4-based cancer vaccine: cytotoxic T lymphocyte epitopes identified in Trovax-vaccinated colorectal cancer patients

Mouse (Murine) Trophoblast Glycoprotein (TPBG) Interaktionspartner

  1. The surface expression of 5T4 marks the use of the CXCR4 (zeige CXCR4 Proteine) rather than the CXCR7 (zeige CXCR7 Proteine) receptor, with distinct consequences for CXCL12 (zeige CXCL12 Proteine) exposure.

  2. 5T4 overexpression in newborn olfactory bulb interneurons facilitates their dendritic arborization even under a sensory input-deprived condition.

  3. molecular interaction of 5T4 and CXCR4 (zeige CXCR4 Proteine) occurring at the cell surface which directly facilitates the biological response to CXCL12 (zeige CXCL12 Proteine)

  4. Spry4 (zeige SPRY4 Proteine) and Tpbg/5T4 were detected in Kit-immunoreactive cells only in Kit(K641E), but not in Kit(WT/WT) animals.

  5. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen

  6. 5T4 glycoprotein expression is associated with early differentiative events of embryonic stem cells

  7. A limited expression profile of 5T4 may contribute to the migration of actively cycling, undifferentiated epithelial progenitor cells during embryogenesis

  8. Because 5T4 is known to interact with actin cytoskeleton, these observations suggest that 5T4 is involved in the formation or maintenance of strata-specific dendritic ramification or synaptic connection of subsets of local interneurons.

  9. E-cadherin (zeige CDH1 Proteine) protein stabilizes cortical actin cytoskeletal arrangement in embryonic stem cells, and this can prevent cell surface localization of the promigratory 5T4 antigen.

TPBG Protein Überblick

Protein Überblick

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Genbezeichner und Symbole assoziert mit TPBG

  • trophoblast glycoprotein (TPBG)
  • trophoblast glycoprotein (Tpbg)
  • trophoblast glycoprotein b (tpbgb)
  • trophoblast glycoprotein (tpbg)
  • 5T4 Protein
  • 5T4AG Protein
  • AW495680 Protein
  • M6P1 Protein
  • tpbg Protein

Bezeichner auf Proteinebene für TPBG

5T4 oncofetal antigen , 5T4 oncofetal trophoblast glycoprotein , 5T4 oncotrophoblast glycoprotein , trophoblast glycoprotein , sc:d0347 , Trophoblast glycoprotein , trophoblast glycoprotein-like

GENE ID SPEZIES
7162 Homo sapiens
21983 Mus musculus
83684 Rattus norvegicus
462850 Pan troglodytes
481899 Canis lupus familiaris
540358 Bos taurus
772098 Gallus gallus
792712 Danio rerio
100286624 Salmo salar
100379816 Xenopus (Silurana) tropicalis
100405225 Callithrix jacchus
100444954 Pongo abelii
Ausgewählte Anbieter für TPBG Proteine (TPBG)
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