anti-Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Antikörper

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. Zusätzlich bieten wir Ihnen Sodium Channel, Voltage-Gated, Type I, beta Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SCN1B 20266 P97952
SCN1B 29686 Q00954
SCN1B 6324 Q07699
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Sodium Channel, Voltage-Gated, Type I, beta Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SCN1B Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Scn1b Antibody Titration: 1.0 ug/ml Positive Control: Rat Thymus 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB SCN1B Antibody (N-Term)  western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the SCN1B antibody detected the SCN1B protein (arrow). SCN1B Antibody (N-Term)  immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.  This data demonstrates the use of the SCN1B Antibody (N-Term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow Cytometric analysis of Hela cells using SCN1B Antibody (N-Term) Cat.-No AP53815PU-N (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human brain tissue stained with SCN1B Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SCN1B Antibody (N-Term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Western blot with SCN1B Polyclonal Antibody 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details
Hund Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using SCN1B antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$669.17
Details
Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

SCN1B Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) , , , ,


, , , , , , , , , , , , , , , , , ,
Rat (Rattus) , , , ,


, , , , , , , , , , , , , , , ,
Human , , , ,


, , , , , , , , , , , , , , , , , ,

Weitere Antikörper gegen Sodium Channel, Voltage-Gated, Type I, beta Interaktionspartner

Mouse (Murine) Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Interaktionspartner

  1. Loss of Scn1b caused increased amplitude of tetrodotoxin-sensitive INa (zeige INA Antikörper), delayed after-depolarizations, triggered beats, changed Ca2 (zeige CA2 Antikörper)+ transients,and susceptibility ventricular arrhythmias.

  2. Study showed that Scn1b is widely expressed at axon initial segments across the mouse brain, there is considerable heterogeneity in the proportion of Scn1b-positive neurons and the amount of expression between and within brain regions

  3. Scn1b mutant subicular and layer 2/3 pyramidal neurons had increased action potential firing rates, presumably as a consequence of their increased input resistance

  4. Stronger expressions of SCN5a (zeige SCN5A Antikörper), SCN1b and Kir2.1 (zeige KCNJ2 Antikörper) were observed in ventricular-like and atrial-like cells compared to that of pacemaker-like cardiomyocytes.

  5. Scn1b is critical for neuronal proliferation, migration, and pathfinding during the critical postnatal period of brain development.

  6. The results presented here identify Navbeta1 as a component of native neuronal Kv4.2 (zeige KCND2 Antikörper)-encoded I(A) channel complexes and a novel regulator of I(A) channel densities and neuronal excitability.

  7. Scn1b regulates the electrical excitability of nociceptive DRG neurons in vivo by modulating both I(Na) and I(K).

  8. propose reciprocity of function between Scn1b (beta1) and Na(v)1.6 such that beta1-mediated neurite outgrowth requires Na(v)1.6-mediated I(Na), and Na(v)1.6 localization and consequent high-frequency firing require beta1

  9. The primary sodium channels present in ventricular myocytes are composed of Na(v)1.5 plus beta2 and/or beta4 subunits in intercalated disks and Na(v)1.1, Na(v)1.3 (zeige SCN3A Antikörper), and Na(v)1.6 plus beta1 and/or beta3 subunits in the transverse tubules.

  10. Floxed allele for conditional inactivation of the voltage-gated sodium channel beta1 subunit Scn1b.

Human Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Interaktionspartner

  1. Contribution of Cardiac Sodium Channel (zeige SCN5A Antikörper) beta-Subunit (zeige POLG Antikörper) Variants to Brugada Syndrome.

  2. SCN1B gene mutations that reduce sodium channel current may provide a mechanistic link between Atrioventricular nodal reentrant tachycardia and Brugada syndrome and predispose to expression of both phenotypes.

  3. In a nonreferred nationwide Danish cohort of SIDS (zeige IDS Antikörper) cases, up to 5/66 (7.5%) of SIDS (zeige IDS Antikörper) cases can be explained by genetic variants in the sodium channel complex genes.

  4. We also identified an SCN1B T189M variant in 2 probands with lone AF and in 1 of 250 control subjects.

  5. Study showed that the human SCN1B C121W epilepsy mutation leads to decreased axon initial segments expression of SCN1B in heterozygous CW mice and a complete lack of SCN1B in homozygous WW mice

  6. High SCN1B expression is associated with increased tumour growth and metastasis in breast cancer.

  7. experimental data indicate that sodium channel voltage-gated type I beta subunit (Navbeta1b)/H162P results in reduced sodium channel activity functionally affecting the ventricular action potential.

  8. SCN1B mutation is not a common cause of Dravet syndrome.

  9. results suggest that R214Q variation in SCN1Bb is a functional polymorphism that may serve as a modifier of the substrate responsible for Brugada syndrome or SIDS (zeige IDS Antikörper) phenotypes

  10. Mutation analysis of the SCN1B, SCN1A (zeige SCN1A Antikörper) and GABRG2 (zeige GABRG2 Antikörper) genes in children affected by Genetic (Generalised) Epilepsy with Febrile Seizures plus was performed

Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Antigen-Profil

Protein Überblick

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SCN1B

  • sodium channel, voltage-gated, type I, beta (Scn1b) Antikörper
  • sodium voltage-gated channel beta subunit 1 (Scn1b) Antikörper
  • sodium voltage-gated channel beta subunit 1 (SCN1B) Antikörper
  • GEFSP1 Antikörper

Bezeichner auf Proteinebene für SCN1B

sodium channel subunit beta-1 , sodium channel, voltage-gated, type I, beta polypeptide , sodium channel voltage-gated type 1 beta polypeptide , sodium channel voltage-gated type I beta polypeptide , sodium channel, voltage-gated, type 1, beta polypeptide , sodium channel beta-1 subunit , sodium channel beta 1-subunit

GENE ID SPEZIES
20266 Mus musculus
29686 Rattus norvegicus
6324 Homo sapiens
484584 Canis lupus familiaris
618204 Bos taurus
100009211 Oryctolagus cuniculus
747705 Pan troglodytes
Ausgewählte Anbieter für anti-Sodium Channel, Voltage-Gated, Type I, beta (SCN1B) Antikörper
Haben Sie etwas anderes gesucht?