anti-Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) Antikörper

The protein encoded by SEL1L is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Zusätzlich bieten wir Ihnen SEL1L Proteine (4) und SEL1L Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SEL1L 6400 Q9UBV2
SEL1L 20338 Q9Z2G6
SEL1L 314352 Q80Z70
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Top anti-SEL1L Antikörper auf antikoerper-online.de

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB SEL1L Antibody (Center) (ABIN654642) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN263220 (1µg/ml) staining of HepG2 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of SEL1L Antibody (N-term) Cat.-No AP53838PU-N in T47D cell line lysates (35ug/lane). This demonstrates the SEL1L antibody detected the SEL1L protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow cytometric analysis of MCF-7 cells using SEL1L Antibody (Center) Cat.-No AP53837PU-N (Right histogram) compared to a negative control cell (Left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in Formalin Fixed, Paraffin Embedded Human pancreas tissue stained with SEL1L antibody (Center) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SEL1L antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Hund Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$455.40
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: SEL1L Antibody [ABIN4087183] - (1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti-SEL1L Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert WB SEL1L Antibody (N-term)  western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SEL1L antibody detected the SEL1L protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details

SEL1L Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-SEL1L Antikörper

  1. Human Polyclonal SEL1L Primary Antibody für ELISA, WB - ABIN408718 : Schelhaas, Malmström, Pelkmans, Haugstetter, Ellgaard, Grünewald, Helenius: Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells. in Cell 2007 (PubMed)

Weitere Antikörper gegen SEL1L Interaktionspartner

Human Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) Interaktionspartner

  1. The SEL1L critically regulates HRD1 (zeige SYVN1 Antikörper)-mediated disposal of misfolded cargo through its short membrane spanning stretch.

  2. this is the first study reporting a significant association of the SEL1L SNP rs12435998 constitutive genetic variant with an improved overall survival in glioblastoma multiforme patients

  3. Low expression of SEL1L is associated with pancreatic ductal adenocarcinoma.

  4. Data revealed close interaction of these two proteins in regulating the cross-talk between extracellular matrix and insulin (zeige INS Antikörper) signalling to create a favourable micro-environment for ss-cell development and function.

  5. SEL1L down-modulation synergy enhances valporic acid cytotoxic effects by influencing glioma stem cells proliferation and self-renewal properties.

  6. ATF6 (zeige ATF6 Antikörper) represents a novel type of ERAD-Lm substrate requiring SEL1L for degradation despite its transmembrane nature.

  7. ERdj5 (zeige DNAJC10 Antikörper), by binding to Sel1L, triggers BiP (zeige GDF10 Antikörper)-Cholera toxin interaction proximal to the Hrd1 (zeige SYVN1 Antikörper) complex; postulate this scenario enables the Hrd1 (zeige SYVN1 Antikörper)-associated retrotranslocation machinery to capture the toxin efficiently once the toxin is released from BiP (zeige GDF10 Antikörper)

  8. SEL1L expression is a potential colorectal cancer (CRC (zeige CALR Antikörper)) tissue biomarker since its expression is significantly higher in adenoma cells with respect to normal mucosa; the levels of expression decrease in undifferentiated CRC (zeige CALR Antikörper) cancers

  9. the rs12435998 SNP in SEL1L gene plays a role in modifying age at diagnosis of PDA in Caucasian nonsmokers.

  10. Two new SEL1L variants are engaged in endosomal trafficking and secretion via vesicles, which could contribute to relieve ER stress in tumorigenic cells.

Mouse (Murine) Sel-1 Suppressor of Lin-12-Like (C. Elegans) (SEL1L) Interaktionspartner

  1. This study implicates Endoplasmic reticulum (ER)-associated degradation mediated by Sel1L-Hrd1 (zeige SYVN1 Antikörper) as a key regulator of B cell development.

  2. Mice deficient for ERAD machinery component Sel1L develop central diabetes insipidus

  3. The authors propose that certain Sel1-Like Repeat motifs of SEL1L play a unique role in membrane bound ERAD machinery.

  4. Sel1L-Hrd1 (zeige SYVN1 Antikörper) plays a constitutive role in endoplasmic reticulum associated degradation in epithelial cell biology and the pathogenesis of intestinal inflammation in Crohn's disease.

  5. Data show that inositol requiring enzyme 1alpha (IRE1alpha (zeige ERN1 Antikörper)), the sensor of the unfolded protein response (UPR), is a bona fide substrate of the Sel1L proten-Hrd1 protein (zeige SYVN1 Antikörper) endoplasmic reticulum (ER)-associated degradation (ERAD) complex.

  6. Adipocyte-specific Sel1L-deficient (AKO) mice are resistant to diet-induced obesity. Sel1L stabilizes and prevents LPL (zeige LPL Antikörper) dimers from aggregation in the endoplasmic reticulum.

  7. Data revealed close interaction of these two proteins in regulating the cross-talk between extracellular matrix and insulin (zeige INS Antikörper) signalling to create a favourable micro-environment for ss-cell development and function.

  8. Sel1L is an indispensable component of the mammalian Hrd1 (zeige SYVN1 Antikörper) endoplasmic reticulum-associated degradation and endoplasmic reticulum homeostasis.

  9. a critical and previously unknown function for SEL1L in regulating adult beta-cell function and growth

  10. an essential role for SEL1L in protein quality control during mouse embryonic development.

SEL1L Antigen-Profil

Protein Überblick

The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit SEL1L

  • SEL1L ERAD E3 ligase adaptor subunit (SEL1L) Antikörper
  • sel-1 suppressor of lin-12-like (C. elegans) (Sel1l) Antikörper
  • SEL1L ERAD E3 ligase adaptor subunit (Sel1l) Antikörper
  • sel-1 suppressor of lin-12-like L homeolog (sel1l.L) Antikörper
  • sel-1 suppressor of lin-12-like (C. elegans) (SEL1L) Antikörper
  • sel-1 suppressor of lin-12-like (sel1l) Antikörper
  • AW493766 Antikörper
  • MGC99195 Antikörper
  • mKIAA4137 Antikörper
  • PRO1063 Antikörper
  • Sel-1L Antikörper
  • SEL1-LIKE Antikörper
  • Sel1h Antikörper
  • SEL1L Antikörper
  • SEL1L1 Antikörper

Bezeichner auf Proteinebene für SEL1L

Suppressor of lin 12 (sel-1), C. elegans, homolog of , protein sel-1 homolog 1 , sel-1 suppressor of lin-12-like 1 , suppressor of lin-12-like protein 1 , Sel1 (suppressor of lin-12) 1 homolog , sel-1L , sel-1 suppressor of lin-12-like (C. elegans) , sel-1 suppressor of lin-12-like , protein sel-1 homolog 1-like , Suppressor of lin-12-like protein 1

GENE ID SPEZIES
6400 Homo sapiens
20338 Mus musculus
314352 Rattus norvegicus
423391 Gallus gallus
453080 Pan troglodytes
480409 Canis lupus familiaris
614959 Bos taurus
708651 Macaca mulatta
735099 Xenopus laevis
100052711 Equus caballus
100155424 Sus scrofa
100231514 Taeniopygia guttata
100353303 Oryctolagus cuniculus
100377925 Saccoglossus kowalevskii
100380038 Xenopus (Silurana) tropicalis
100408799 Callithrix jacchus
100477463 Ailuropoda melanoleuca
100548852 Meleagris gallopavo
100583688 Nomascus leucogenys
101834260 Mesocricetus auratus
100730201 Cavia porcellus
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