anti-Runt-Related Transcription Factor 3 (RUNX3) Antikörper

RUNX3 encodes a member of the runt domain-containing family of transcription factors. Zusätzlich bieten wir Ihnen RUNX3 Proteine (13) und RUNX3 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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Top anti-RUNX3 Antikörper auf antikoerper-online.de

Showing 10 out of 215 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-RUNX3 Antibody Titration: 1.25ug/mlELISA Titer: 1:12500Positive Control: NIH/3T3 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Maus Allophycocyanin FACS Detection of RUNX3/CBFA3 in Human PBMC lymphocytes by Flow Cytometry. Human peripheral blood mononuclear cells (PBMC) lymphocytes either (A) untreated or (B) treated with PMA were stained with Mouse Anti-Human RUNX3/CBFA3 APC-conjugated Monoclonal Antibody. Detection of RUNX3/CBFA3 in Human PBMC lymphocytes by Flow Cytometry. Human peripheral blood mononuclear cells (PBMC) lymphocytes either (A) untreated or (B) treated with PMA were stained with Mouse Anti-Human RUNX3/CBFA3 APC-conjugated Monoclonal Antibody. 100 Tests Anmelden zum Anzeigen 3 bis 4 Tage
335,00 €
Details
Human Maus Unkonjugiert FACS, ICC, SimWes, WB Detection of Human RUNX3/CBFA3 by Simple WesternTM. Simple Western lane view shows lysates of Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line, loaded at 0.5 mg/mL. A specific band was detected for RUNX3/CBFA3 at approximately 54 kDa (as indicated) using 10 ug/mL of Mouse Anti-Human/Mouse RUNX3/CBFA3 Monoclonal Antibody. This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Detection of RUNX3/CBFA3 in Human PBMC by Flow Cytometry. Human PBMC unstimulated (light orange filled histogram) or treated with 50ng/mL PMA (dark orange filled histogram) were stained with Mouse Anti-Human/Mouse RUNX3/CBFA3 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
254,00 €
Details
Human Maus Unkonjugiert ICC, FACS, IHC, ELISA, WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
494,23 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- RUNX3 Picoband antibody, IHC(P) IHC(P): Rat Spleen Tissue Anti- RUNX3 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
Details
Maus Kaninchen Unkonjugiert WB Anti- RUNX3 antibody, Western blotting All lanes: Anti RUNX3  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Mouse Liver Tissue Lysate at 50ug Predicted bind size: 44KD Observed bind size: 44KD 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB RUNX3 Antibody (Center) (ABIN658684) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the RUNX3 antibody detected the RUNX3 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Maus Unkonjugiert ELISA, WB RUNX3 polyclonal antibody (A01), Lot # 070226JCSa Western Blot analysis of RUNX3 expression in HepG2 . Western Blot detection against Immunogen (35.57 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details

RUNX3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-RUNX3 Antikörper

  1. Human Polyclonal RUNX3 Primary Antibody für ELISA, WB - ABIN560191 : Nakamura, Senzaki, Yoshikawa, Nishimura, Inoue, Ito, Ozaki, Shiga: Dynamic regulation of the expression of neurotrophin receptors by Runx3. in Development (Cambridge, England) 2008 (PubMed)
    Zeige alle 5 Referenzen für 560191

  2. Human Monoclonal RUNX3 Primary Antibody für FACS, ICC - ABIN4899364 : Chopin, Seillet, Chevrier, Wu, Wang, Morse, Belz, Nutt: Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. in The Journal of experimental medicine 2013 (PubMed)
    Zeige alle 2 Referenzen für 4899364

  3. Human Polyclonal RUNX3 Primary Antibody für IF, IHC (p) - ABIN658684 : Zhu, Xu, Hu, Feng, Jiang, Hou, Cao, Han, Ling, Ge: Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma. in Journal of experimental & clinical cancer research : CR 2015 (PubMed)

  4. Cow (Bovine) Polyclonal RUNX3 Primary Antibody für WB - ABIN2780022 : Yarmus, Woolf, Bernstein, Fainaru, Negreanu, Levanon, Groner: Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

  5. Human Monoclonal RUNX3 Primary Antibody für ICC, FACS - ABIN1724742 : Mei, Bai, Liu, Li, Wu, Yu, Zheng: RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration. in Journal of cancer research and clinical oncology 2011 (PubMed)

Weitere Antikörper gegen RUNX3 Interaktionspartner

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. In neuronal fate determination, Runx co-factor Cbfbeta (zeige CBFB Antikörper) is essential for its function, but the high level of Runx3 expression can overcome the loss of Cbfbeta (zeige CBFB Antikörper), demonstrating that Cbfbeta (zeige CBFB Antikörper) in this context serves solely as a signal amplifier of Runx3 activity.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (zeige RUNX1 Antikörper)-expressing cells in the ventral wall of the dorsal aorta.

  4. Zebrafish embryos lacking Rad21 (zeige RAD21 Antikörper), or cohesin subunit Smc3 (zeige SMC3 Antikörper), fail to express runx3 and lose hematopoietic runx1 (zeige RUNX1 Antikörper) expression in early embryonic development.

Pig (Porcine) Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. These results demonstrate that the CRISPR/Cas9 system is effective in inducing mutations on a specific locus of genome and the RUNX3 knockout pigs can be useful resources for human cancer research and to develop novel cancer therapies.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. Runx3-deficient CD8 (zeige CD8A Antikörper)(+) cytotoxic effector T cells aberrantly upregulated genes characteristic of follicular helper T (TFH) cell lineage, including Bcl6 (zeige BCL6 Antikörper), Tcf7 (zeige TCF7 Antikörper) and Cxcr5 (zeige CXCR5 Antikörper). Mechanistically, the Runx3-CBFbeta (zeige CBFB Antikörper) transcription factor complex deployed H3K27me3 to Bcl6 (zeige BCL6 Antikörper) and Tcf7 (zeige TCF7 Antikörper) genes to suppress the TFH program.

  2. Deletion of Runx3 in the peripheral nervous system or specifically in peripheral sensory neurons, or of enhancer elements driving Runx3 expression in proprioceptive neurons, induced prepubertal scoliosis.

  3. We found that Runx3 exerted a positive effect on early myeloid development

  4. Runx3 plays a crucial role in the hypothalamo-pituitary-gonadal axis

  5. intricate combinatorial interplay among the three regulatory elements governs Runx3 expression in distinct subtypes of TrkC (zeige NTRK3 Antikörper) neurons while concomitantly extinguishing its expression in non-TrkC (zeige NTRK3 Antikörper) neurons

  6. this study identifies a compensatory signaling mechanism that prevents lineage-fate errors by dynamically modulating Runx3d induction rates during MHC I positive selection

  7. our data suggest that Runx3 may play a crucial role in the development of DRGs by regulating the expression of Ntrk3 (zeige NTRK3 Antikörper) variants

  8. Runx3 is crucial for the phenotypic and functional changes observed in ThPok (zeige ZBTB7B Antikörper)-deficient invariant natural killer T cells.

  9. the transcription factor Runx3 was essential for the normal development of subsets of innate lymphoid cells (ILCs) in the mucosa

  10. Runx1 and Runx3 are the downstream effectors of Nanog, especially in the early and intermediate osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2.

Human Runt-Related Transcription Factor 3 (RUNX3) Interaktionspartner

  1. High RUNX3 expression is associated with gastric cancer.

  2. we present evidence that RUNX3 can act as a tumor suppressor in a human T-cell malignancy and suggest that this effect is predominantly mediated through transcripts from its distal promoter, in particular RUNX3/p46 (zeige POLDIP3 Antikörper).

  3. Our results from clinical samples also suggest that Threonine 209 phosphorylation by Pak1 (zeige PAK1 Antikörper) could be a potential therapeutic target and of great clinical relevance with implications for Runx3 inactivation in cancer cells where Runx3 is known to be oncogenic. The findings presented in this study provide evidence of Runx3-Threonine 209 phosphorylation as a molecular switch in dictating the tissue-specific dualistic functions

  4. RUNX3 acts as a tumour suppressor

  5. MicroRNA-145 could regulate the balance of Th1 (zeige TH1L Antikörper)/Th2 through targeting the RUNX3 in asthma patients.

  6. The miR (zeige MLXIP Antikörper)-29b/KDM2A (zeige KDM2A Antikörper) axis was involved in the RUNX3-mediated inhibition of gastric cancer cell proliferation and metastasis.

  7. RUNX3 methylation level is associated with gastric cancer (GC), especially the methylation at site -1415 contributes to the poor prognosis in GC.

  8. The hypermethylation of RUNX3 in AFB1-transformed hepatocytes and human hepatocellular carcinomas implicates RUNX3 as a tumor suppressor gene

  9. our results suggest that an aberrant messenger RNA expression may be the outcome of CpG, CHG, and CHH methylation in O(6)-methylguanine-DNA methyltransferase, whereas outcome of CHG and CHH methylation in runt-related transcription factor 3 promoters along with risk factors such as consumption of tobacco, betel nut, and smoking habits in esophageal cancer from Northeast India

  10. IFNgamma promotes double strabded RNA-induced TLR3 (zeige TLR3 Antikörper)-dependent apoptosis via upregulation of transcription factor Runx3 in airway epithelial cells.

RUNX3 Antigen-Profil

Protein Überblick

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit RUNX3

  • runt-related transcription factor 3 (runx3) Antikörper
  • runt-related transcription factor 3 (RUNX3) Antikörper
  • frRunx3/p45 (frrunx3) Antikörper
  • runt related transcription factor 3 (Runx3) Antikörper
  • runt-related transcription factor 3 (Runx3) Antikörper
  • AML2 Antikörper
  • Cbfa3 Antikörper
  • frrunx3 Antikörper
  • Pebp2a3 Antikörper
  • PEBP2aC Antikörper
  • runx3 Antikörper
  • runxb Antikörper

Bezeichner auf Proteinebene für RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

GENE ID SPEZIES
58127 Danio rerio
403159 Sus scrofa
456633 Pan troglodytes
100049632 Takifugu rubripes
100474431 Ailuropoda melanoleuca
100500732 Xenopus laevis
12399 Mus musculus
864 Homo sapiens
617389 Bos taurus
156726 Rattus norvegicus
769687 Gallus gallus
487366 Canis lupus familiaris
Ausgewählte Anbieter für anti-RUNX3 (RUNX3) Antikörper
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