RUNX3 Antikörper (AA 210-429)
Kurzübersicht für RUNX3 Antikörper (AA 210-429) (ABIN6147314)
Target
Alle RUNX3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 210-429
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Sequenz
- DRFGDLERLR MRVTPSTPSP RGSLSTTSHF SSQPQTPIQG TSELNPFSDP RQFDRSFPTL PTLTESRFPD PRMHYPGAMS AAFPYSATPS GTSISSLSVA GMPATSRFHH TYLPPPYPGA PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT SSAASVAAGN LMNPSLGGQS DGVEADGSHS NSPTALSTPG RMDEAVWRPY
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 210-429 of human RUNX3 (NP_001026850.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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Andere Bezeichnung
- RUNX3
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Hintergrund
- This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.,RUNX3,AML2,CBFA3,PEBP2aC,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Target gene,RUNX3
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Molekulargewicht
- 44 kDa/45 kDa
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Gen-ID
- 864
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UniProt
- Q13761
Target
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