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Proprotein Convertase Subtilisin/kexin Type 4 Proteine (PCSK4)

PCSK4 encodes a member of the subtilisin-like proprotein convertase family. Zusätzlich bieten wir Ihnen PCSK4 Antikörper (52) und PCSK4 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PCSK4 29596 P20695
PCSK4 54760 Q6UW60
PCSK4 18551 P29121
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Top PCSK4 Proteine auf antikoerper-online.de

Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 46 bis 51 Tage
5.743,80 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 56 Days
7.380,00 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
3.457,14 €
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HOST_Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 1 bis 3 Tage
469,44 €
Details

PCSK4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Rat (Rattus)

Human , ,
,
Mouse (Murine)

Weitere Proteine zu Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartnern

Human Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartner

  1. Maturation by propeptide removal occurs very inefficiently when rat or human proPCSK4 is overexpressed in HEK293 cells where it interacts with BiP.

  2. abnormal processing of IGF-II by PC4 (zeige IFRD1 Proteine) may represent a previously uncharacterized mechanism involved in the pathophysiology of fetoplacental growth restriction

Mouse (Murine) Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4) Interaktionspartner

  1. These observations indicate that non-histone chromatin-associated proteins like PC4 (zeige IFRD1 Proteine) play a significant role in neuronal plasticity.

  2. Results suggest that positive cofactor 4 (Pc4) has an important role in inducing spontaneous somatic cell reprogramming via up-regulation of key pluripotency genes.

  3. CRES (zeige CST8 Proteine) may be a regulator of PC4 (zeige IFRD1 Proteine) in sperm-egg interaction and fertilization.

  4. Data suggest that the fertility defect in PCSK4 knockout mice is due, in part, to altered processing/proteolysis of ACRBP (zeige ACRBP Proteine) (proacrosin/acrosin (zeige ACR Proteine) binding protein sp32 (zeige ACRBP Proteine)) as well as structural abnormalities in sperm heads and acrosomes.

  5. thatADAM2may be a natural substrate of sperm PCSK4 and its cleavage by the enzyme during acrosome reaction may be relevant to the fertilization process.

  6. Efficient activation and trafficking of PCSK4 requires a special environment, which presumably exists in testicular germ cells where it is highly expressed, but not in somatic cells where it is not or is barely expressed.

  7. Alterations in signal transduction and proteolytic processing during in vitro capacitation may underlie the fertilization incompetence of PCSK4-null sperm.

  8. PCSK4-null sperm underwent capacitation at a faster rate; they were induced to acrosome react by lower concentrations of zona pellucida; and their egg-binding ability was only half that of wild-type sperm.

  9. Redox-mediated upregulation of hepatocyte iNOS (zeige NOS2 Proteine) transcription requires an HNF-4alpha (zeige HNF4A Proteine)-PC4 (zeige IFRD1 Proteine) transcriptional complex

  10. Report recruitment of RNA polymerase II cofactor PC4 (zeige IFRD1 Proteine) to DNA damage sites.

PCSK4 Protein Überblick

Protein Überblick

This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in reproduction and processes multiple prohormones including pro-pituitary adenylate cyclase-activating protein (proPACAP) and pro-insulin-like growth factor II.

Genbezeichner und Symbole assoziert mit PCSK4

  • proprotein convertase subtilisin/kexin type 4 (PCSK4)
  • proprotein convertase subtilisin/kexin type 4 (pcsk4)
  • interferon-related developmental regulator 1 (Ifrd1)
  • proprotein convertase subtilisin/kexin type 4 (Pcsk4)
  • SUB1 homolog (S. cerevisiae) (Sub1)
  • AI647044 Protein
  • AI842364 Protein
  • L21221 Protein
  • MGC146505 Protein
  • NEC 3 Protein
  • NEC3 Protein
  • P9 Protein
  • P15 Protein
  • PC4 Protein
  • PCSK4 Protein
  • Rpo2tc1 Protein
  • SPC5 Protein

Bezeichner auf Proteinebene für PCSK4

proprotein convertase subtilisin/kexin type 4 , IRPR , nerve growth factor-inducible protein PC4 , KEX2-like endoprotease 3 , neuroendocrine convertase 3 , prohormone convertase 3 , NEC 3 , PC4 , RNA polymerase II transcriptional coactivator , activated RNA polymerase II transcriptional coactivator p15 , p14 , positive cofactor 4 , single-stranded DNA-binding protein p9

GENE ID SPEZIES
485083 Canis lupus familiaris
508744 Bos taurus
707567 Macaca mulatta
779814 Xenopus (Silurana) tropicalis
749996 Pan troglodytes
29596 Rattus norvegicus
54760 Homo sapiens
18551 Mus musculus
171085 Rattus norvegicus
20024 Mus musculus
Ausgewählte Anbieter für PCSK4 Proteine (PCSK4)
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