anti-Prolylcarboxypeptidase (PRCP) Antikörper

The protein encoded by PRCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. Zusätzlich bieten wir Ihnen Prolylcarboxypeptidase Kits (41) und Prolylcarboxypeptidase Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PRCP 649 P13497
PRCP 72461 Q7TMR0
PRCP 293118  
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Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in MicroplateReader by 450nm. Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in Microplate Reader by 450nm 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
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Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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PRCP Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Prolylcarboxypeptidase Interaktionspartner

Human Prolylcarboxypeptidase (PRCP) Interaktionspartner

  1. Data show that the KKN1 fragment generated by BMP1 (zeige BMP1 Antikörper)-cleavage of WFIKKN1 (zeige WFIKKN1 Antikörper) protein contributes most significantly to the observed enhancer activity.

  2. For the first time, PRCP is identified as an apelin (zeige APLN Antikörper)-cleaving enzyme.

  3. a previously unknown O-glycosylation site and Asn-hydroxylation site, indicating a novel feature of BMP-1 (zeige BMP1 Antikörper) in the EGF (zeige EGF Antikörper) domain. The study clearly outlines the benefit of in-depth characterization of overexpressed proteins to deduce important protein modifications.

  4. BMP-1 (zeige BMP1 Antikörper) accelerates the connective tissue growth factor (zeige CTGF Antikörper) production dependently on cellular internalization in human dental pulp cells, indicating a novel property of BMP-1 (zeige BMP1 Antikörper) which potentially enhances bone-like reparative dentin formation.

  5. Studies indicate crosstalk between Notch receptor and Wnt protein, Hedgehog protein, hypoxia and transforming growth factor beta (TGFbeta)/bone morphogenetic protein (BMP) pathways.

  6. study thus highlights the severe and progressive nature of BMP1 (zeige BMP1 Antikörper)-associated OI in adults and broadens insights into the functional consequences of BMP1/mTLD-deficiency on ECM (zeige MMRN1 Antikörper) organization.

  7. Data indicate that BMP-1 (zeige BMP1 Antikörper) can simultaneously trigger matrix assembly and boost the synthesis of matrix proteins via a direct effect on growth factors in the contexts of development, growth and tissue repair. [review]

  8. The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome

  9. Two novel variants in the BMP1 (zeige BMP1 Antikörper) gene: c.808A>G and c.1297G>T care associated with osteogenesis imperfecta (zeige COL1A2 Antikörper).

  10. Frequent bone fracture in children is cause by BMP1 (zeige BMP1 Antikörper)-1 deficiency.

Mouse (Murine) Prolylcarboxypeptidase (PRCP) Interaktionspartner

  1. This study demonistrated that PRCP gene is broadly expressed in the brain.

  2. PRCP regulates cell growth, angiogenesis, and the response to vascular injury

  3. ACE2 (zeige ACE2 Antikörper) metabolizes ANG II (zeige AGT Antikörper) in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.

  4. PRCP is an important regulator of energy and glucose homeostasis since its deletion significantly improves metabolic parameters in mice exposed to both standard chow diet and high-fat diet

  5. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

  6. This study showed that PRCP mutant mice have a significant decrease in fat mass, although an increase in lean mass was also observed; reduced leptin (zeige LEP Antikörper) levels and increased energy expenditure were also found.

  7. Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

  8. PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels.

Prolylcarboxypeptidase (PRCP) Antigen-Profil

Protein Überblick

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Genbezeichner und Symbole assoziert mit PRCP

  • prolylcarboxypeptidase (angiotensinase C) (PRCP) Antikörper
  • prolylcarboxypeptidase (angiotensinase C) (prcp) Antikörper
  • prolylcarboxypeptidase (AaeL_AAEL005521) Antikörper
  • prolylcarboxypeptidase (CpipJ_CPIJ006123) Antikörper
  • prolylcarboxypeptidase (CpipJ_CPIJ006124) Antikörper
  • bone morphogenetic protein 1 (BMP1) Antikörper
  • prolylcarboxypeptidase (angiotensinase C) (Prcp) Antikörper
  • 2510048K03Rik Antikörper
  • 2610104A14Rik Antikörper
  • AI451719 Antikörper
  • HUMPCP Antikörper
  • MGC145178 Antikörper
  • OI13 Antikörper
  • PCOLC Antikörper
  • PCP Antikörper
  • PCP2 Antikörper
  • TLD Antikörper

Bezeichner auf Proteinebene für PRCP

prolylcarboxypeptidase , mammalian tolloid protein , procollagen C-endopeptidase , procollagen C-proteinase , lysosomal Pro-X carboxypeptidase , proline carboxypeptidase , angiotensinase C , lysosomal carboxypeptidase C , prolylcarboxypeptidase isoform 1 preproprotein

GENE ID SPEZIES
100061830 Equus caballus
780095 Xenopus (Silurana) tropicalis
5579822 Aedes aegypti
6038068 Culex quinquefasciatus
6038069 Culex quinquefasciatus
649 Homo sapiens
72461 Mus musculus
5547 Homo sapiens
476788 Canis lupus familiaris
534927 Bos taurus
293118 Rattus norvegicus
100734342 Cavia porcellus
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