PRCP Antikörper

Produktnummer ABIN7130695

Produktdetails anti-PRCP Antikörper

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human PRCP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PRCP

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Andere Bezeichnung: PRCP (PRCP Produkte)

Synonyme: OI13 antikoerper, PCOLC antikoerper, PCP antikoerper, PCP2 antikoerper, TLD antikoerper, humpcp antikoerper, MGC145178 antikoerper, 2510048K03Rik antikoerper, 2610104A14Rik antikoerper, AI451719 antikoerper, HUMPCP antikoerper, zgc:91816 antikoerper, bone morphogenetic protein 1 antikoerper, prolylcarboxypeptidase antikoerper, lysosomal Pro-X carboxypeptidase antikoerper, prolylcarboxypeptidase (angiotensinase C) antikoerper, BMP1 antikoerper, prcp antikoerper, LOC5579822 antikoerper, CpipJ_CPIJ006123 antikoerper, CpipJ_CPIJ006124 antikoerper, Prcp antikoerper, PRCP antikoerper

Hintergrund:

Background: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: Angiotensinase C antibody, HUMPCP antibody, Lysosomal carboxypeptidase C antibody, Lysosomal Pro X carboxypeptidase antibody, Lysosomal Pro-X carboxypeptidase antibody, MGC2202 antibody, PCP antibody, PCP_HUMAN antibody, PRCP antibody, Proline carboxypeptidase antibody, Prolylcarboxypeptidase (angiotensinase C) antibody, Prolylcarboxypeptidase antibody, prolylcarboxypeptidase isoform 1 preproprotein antibody

UniProt: P42785