PRCP Antikörper (N-Term)

Produktnummer ABIN657308

Produktdetails anti-PRCP Antikörper

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Bindungsspezifität: AA 114-143, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRCP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of human PRCP.

Klon: RB32742

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu PRCP

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Andere Bezeichnung: PRCP (PRCP Produkte)

Synonyme: OI13 antikoerper, PCOLC antikoerper, PCP antikoerper, PCP2 antikoerper, TLD antikoerper, humpcp antikoerper, MGC145178 antikoerper, 2510048K03Rik antikoerper, 2610104A14Rik antikoerper, AI451719 antikoerper, HUMPCP antikoerper, zgc:91816 antikoerper, bone morphogenetic protein 1 antikoerper, prolylcarboxypeptidase antikoerper, lysosomal Pro-X carboxypeptidase antikoerper, prolylcarboxypeptidase (angiotensinase C) antikoerper, BMP1 antikoerper, prcp antikoerper, LOC5579822 antikoerper, CpipJ_CPIJ006123 antikoerper, CpipJ_CPIJ006124 antikoerper, Prcp antikoerper, PRCP antikoerper

Hintergrund: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq].

Molekulargewicht: 55800

NCBI Accession: NP_005031, NP_955450

UniProt: P42785