anti-Programmed Cell Death 1 (PDCD1) Antikörper

May have a role in the regulation of spermatogenesis.. Zusätzlich bieten wir Ihnen PD-1 Proteine (93) und PD-1 Kits (25) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDCD1 5133 Q15116
PDCD1 301626  
PDCD1 18566 Q02242
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Top anti-PD-1 Antikörper auf antikoerper-online.de

Showing 10 out of 671 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml Lane 1: JURKAT Whole Cell Lysate at 40ug Lane 2: Human Placenta Tissue Lysate at 50ug Predicted bind size: 32KD Observed bind size: 38KD Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml WB: Recombinant Human PD1 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Ziege Biotin ELISA (Detection), FACS, WB Detection of PD-1 in Human PBMCs treated with PHA by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ug/mL PHA overnight were stained with Goat Anti-Human PD-1 Biotinylated Antigen Affinity-purified Polyclonal Antibody. Detection of PD-1 in Human PBMCs treated with PHA by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ug/mL PHA overnight were stained with Goat Anti-Human PD-1 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 50 μg Anmelden zum Anzeigen 8 bis 9 Tage
$404.25
Details
Maus Ziege Unkonjugiert CyTOF, FACS, IHC, WB PD-1 in Mouse Spleen. PD-1 was detected in perfusion fixed frozen sections of mouse spleen using Goat Anti-Mouse PD-1 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm in splenocytes. PD-1 in Mouse Thymus. PD-1 was detected in perfusion fixed frozen sections of mouse thymus using 15 ug/mL Mouse PD-1 Antigen Affinity-purified Polyclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$393.75
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of CD279 expression in THP1 (A), HepG2 (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185400 (0.6µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Maus Unkonjugiert EIA, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Maus Hamster Biotin FACS 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$308.00
Details
Maus Hamster Unkonjugiert FACS 0.25 mg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Maus Unkonjugiert CyTOF, FACS, WB Detection of PD-1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ng/mL PHA for 2 days were stained with Mouse Anti-Human PD-1 Monoclonal Antibody. Detection of Human PD-1 by Western Blot. Western blot shows lysates of HEK293 human embryonic kidney cell line either mock transfected or transfected with human PD-1. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human PD-1 Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$309.75
Details
Maus Ziege PE FACS Detection of PD-1 in Mouse CD4+ T-Cells by Flow Cytometry. Mouse CD4+ T-cells were stained with Goat Anti-Mouse PD-1 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. Detection of PD-1 in Mouse CD4+ T-Cells by Flow Cytometry. Mouse CD4+ T-cells were stained with Goat Anti-Mouse PD-1 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$315.00
Details

PDCD1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-PD-1 Antikörper

  1. Human Monoclonal PD-1 Primary Antibody für BR, FACS - ABIN2689142 : Bennett, Luxenberg, Ling, Wang, Marquette, Lowe, Khan, Veldman, Jacobs, Valge-Archer, Collins, Carreno: Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 8 Pubmed References

  2. Mouse (Murine) Monoclonal PD-1 Primary Antibody für BR, FACS - ABIN2689141 : Nishimura, Agata, Kawasaki, Sato, Imamura, Minato, Yagita, Nakano, Honjo: Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. in International immunology 1997 (PubMed)
    Show all 7 Pubmed References

  3. Human Polyclonal PD-1 Primary Antibody für ELISA (Detection), FACS - ABIN4899871 : Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. in Journal of neuroimmunology 2008 (PubMed)
    Show all 7 Pubmed References

  4. Human Polyclonal PD-1 Primary Antibody für IHC, ELISA - ABIN1002980 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal PD-1 Primary Antibody für IHC, ELISA - ABIN1002981 : Ishida, Agata, Shibahara, Honjo: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. in The EMBO journal 1992 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal PD-1 Primary Antibody für IF (p), IHC (p) - ABIN735608 : Zhang, Niyazi, Hong, Tuluwengjiang, Zhang, Zhang, Su, Bao: Effect of EBI3 on radiation-induced immunosuppression of cervical cancer HeLa cells by regulating Treg cells through PD-1/PD-L1 pathway. in Tumour biology 2017 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal PD-1 Primary Antibody für ICC, FACS - ABIN438813 : Dorrell, Abraham, Lanxon-Cookson, Canaday, Streeter, Grompe: Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. in Stem cell research 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal PD-1 Primary Antibody für FACS - ABIN2479652 : Ochonisky, Chosidow, Kuentz, Man, Fraitag, Pelisse, Revuz: Cogan's syndrome. An unusual etiology of urticarial vasculitis. in Dermatologica 1992 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal PD-1 Primary Antibody für FACS - ABIN2479653 : Kanai, Totsuka, Uraushihara, Makita, Nakamura, Koganei, Fukushima, Akiba, Yagita, Okumura, Machida, Iwai, Azuma, Chen, Watanabe: Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 3 Pubmed References

  10. Human Monoclonal PD-1 Primary Antibody für FACS - ABIN2479655 : Freeman, Wherry, Ahmed, Sharpe: Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. in The Journal of experimental medicine 2006 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen PD-1 Interaktionspartner

Human Programmed Cell Death 1 (PDCD1) Interaktionspartner

  1. Low PD-1 expression is associated with pediatric solid tumors.

  2. Hypermutation and elevated neoantigen count in glioblastoma occurred in a patient harboring a germline POLE mutation and are associated with a clinical and antitumor immune response to PD-1 blockade

  3. In this discovery cohort, the combination of PD-1 and CTLA-4 (zeige CTLA4 Antikörper) emerged as the best predictor of response. Patients whose tumors had at least 20% of CD8 (zeige CD8A Antikörper)+ T cells expressing these two markers had a median progression-free survival of 31.6 months, versus 9.6 months for patients with less than 20% of this subtype among their tumor CD8 (zeige CD8A Antikörper)+ cells

  4. Findings suggest that tumor microenvirnment-derived TGF-beta1 (zeige TGFB1 Antikörper) directly augments PD-1 expression on tumor infiltrating lymphocytes, suppressing CD8 (zeige CD8A Antikörper)+ T cells that engage tumor antigens and enhancing tumor immune resistance.

  5. PD-1 was upregulated in Tregs of patients with sepsis and may indicate a state of immune dysfunction. Overexpression of PD-1 in Tregs was associated with more severe sepsis as well as poor outcomes.

  6. This review focuses on the pathogenesis, clinical manifestations and management of immune-related toxicity of anti-CTLA-4 (zeige CTLA4 Antikörper) and anti-PD-1 antibodies

  7. soluble PD-1 is elevated in critical illness and may represent a potential biomarker for Acute respiratory distress syndrome.

  8. Together, our results suggest an important role of PD-1 in glioma-induced immune escape, and provide translational evidence for the use of PD-1 blocking antibodies in human malignant gliomas.

  9. High PD1 expression is associated with head and neck cancer.

  10. Decreased expression of PD1 mRNA led to Left ventricular dysfunction and functional dysregulation of cellular immunity that may work in the etiopathogenesis of Peripartum Cardiomyopathy.

Mouse (Murine) Programmed Cell Death 1 (PDCD1) Interaktionspartner

  1. data suggest that increased expression of checkpoint blockade molecules PD-1 and CTLA-4 (zeige CTLA4 Antikörper) on donor T cells is not sufficient to prevent GvHD, and that cooperation between checkpoint blockade signaling by host cells and donor Tregs is necessary to limit GvHD in allo-HSCT recipients

  2. PD-1 Blockade Promotes Epitope Spreading in Anticancer CD8 (zeige CD8A Antikörper)(+) T Cell Responses by Preventing Fratricidal Death of Subdominant Clones To Relieve Immunodomination

  3. Adoptive transfer of murine T cells expressing a chimeric-PD1-Dap10 (zeige HCST Antikörper) receptor may induce a preferential cytokine profile and T-cell differentiation phenotype for anti-lymphoma therapies.

  4. soluble PD-1 is elevated in critical illness and may represent a potential biomarker for Acute respiratory distress syndrome.

  5. Together, our results suggest an important role of PD-1 in glioma-induced immune escape, and provide translational evidence for the use of PD-1 blocking antibodies in human malignant gliomas.

  6. study found that Bcl6 positively regulates PD-1 expression by inhibiting the ability of T-bet/Tbx21 to repress Pdcd1 transcription.

  7. PD-L1 (zeige CD274 Antikörper) selectively enhances T cell-mediated immune responses, driving graft-versus-host disease lethality and suggesting a context-dependent function of the PD-1/PD-L1 (zeige CD274 Antikörper) axis

  8. PD-1 is required for maintaining the number, and hence function, of KLRG1 (zeige KLRG1 Antikörper)(+) Group 2 innate lymphoid cells.

  9. this study shows that PD-1 regulates early glycolytic and mitochondrial alterations in virus-specific CD8 (zeige CD8A Antikörper)+ T cells generated during infection, and represses transcriptional coactivator PGC-1alpha (zeige PPARGC1A Antikörper)

  10. Our results suggest that anti-PD-1 antibody treatment has little effect on afatinib-induced lung injury.

PD-1 (PDCD1) Antigen-Profil

Protein Überblick

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Genbezeichner und Symbole assoziert mit PDCD1

  • programmed cell death 1 (PDCD1) Antikörper
  • programmed cell death 1 (Pdcd1) Antikörper
  • CD279 Antikörper
  • hPD-1 Antikörper
  • hPD-l Antikörper
  • Ly101 Antikörper
  • PD-1 Antikörper
  • PD1 Antikörper
  • Pdc1 Antikörper
  • SLEB2 Antikörper

Bezeichner auf Proteinebene für PDCD1

programmed cell death protein 1 , protein PD-1 , programmed cell death 1 , programmed death 1 , mPD-1

GENE ID SPEZIES
5133 Homo sapiens
301626 Rattus norvegicus
424913 Gallus gallus
613842 Bos taurus
18566 Mus musculus
486213 Canis lupus familiaris
100135775 Macaca mulatta
Ausgewählte Anbieter für anti-PD-1 (PDCD1) Antikörper
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