anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antikörper

PABPC1 encodes a poly(A) binding protein. Zusätzlich bieten wir Ihnen Poly(A) Binding Protein, Cytoplasmic 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PABPC1 26986 P11940
PABPC1 18458 P29341
PABPC1 171350 Q9EPH8
Direkt bei antikoerper-online bestellen
  • +49 (0)241 95 163 153
  • +49 (0)241 95 163 155
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-Poly(A) Binding Protein, Cytoplasmic 1 Antikörper auf antikoerper-online.de

Showing 10 out of 75 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-PABPC1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate Sample Type: Human brain stem cells (NT2) </br> <br />Primary Antibody Dilution: 1:500</br><br />Secondary Antibody: Goat anti-rabbit Alexa Fluor 594</br> <br />Secondary Antibody Dilution: 1:0000</br>Color/Signal Descriptions: Red: PABPC1 Blue: DAPI</br> <br /> Gene Name: PABPC1</br> <br /><br />Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Maus Unkonjugiert CyTOF, ELISA, FACS, ICC, IF, IP, MA, WB Western Blot: PABP Antibody (10E10) [ABIN267505] - Cell line lysates were separated on SDS-PAGE and probed with 1 ug/mL Monoclonal Anti-PABP Clone: 10E10. The antibody was developed using Goat Anti-Mouse IgG-Peroxidase and a chemiluminescent substrate. (1) HEK293T, (2) HeLa, (3) G361 and (4) COS-7. Immunocytochemistry/Immunofluorescence: PABP Antibody (10E10) [ABIN267505] - PABP antibody was tested in HeLa cells at a 1:50 dilution using a Dylight 488 conjugated secondary antibody (Green). Actin (Red) and DNA (Blue) were counterstained using Phalloidin 568 and DAPI. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of PABPC1 Antibody (Center) (ABIN389462) in NIH-3T3 cell line lysates (35 µg/lane). PABPC1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PABPC1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of PABPC1 Antibody (Center) in NIH-3T3 cell line lysates (35ug/lane). PABPC1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Huhn Maus Unkonjugiert ICC, FACS, IF, IP, ELISA, WB Western blot for anti-PABP on HeLa cell extracts (left lane) 50 μL Anmelden zum Anzeigen 3 bis 4 Tage
385,00 €
Details
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC, WB 100 μL Anmelden zum Anzeigen 12 Days
392,86 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB IHC-P Image PABP antibody [N1N2], N-term detects PABP protein at cytosol on mouse lung by immunohistochemical analysis. Sample: Paraffin-embedded mouse lung. PABP antibody [N1N2], N-term , dilution: 1:500. IHC-P Image PABP antibody [N1N2], N-term detects PABP protein at cytosol on mouse duodenum by immunohistochemical analysis. Sample: Paraffin-embedded mouse duodenum. PABP antibody [N1N2], N-term , dilution: 1:500. 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
357,24 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Lane 1: mouse heart lysates Lane 2: mouse kidney lysates probed with Anti PABP (Methyl Arg455/460) Polyclonal Antibody, Unconjugated (ABIN704831) at 1:200 in 4C. Followed by conjugation to secondary antibody at 1:3000 90min in 37C. Predicted band 75kD. Observed band size: 75kD Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
326,42 €
Details
Huhn Maus Unkonjugiert IF, IP, ELISA, WB 50 μL Anmelden zum Anzeigen 11 bis 14 Tage
679,21 €
Details

PABPC1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) ,


, , , , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , , , ,

Am meisten referenzierte anti-Poly(A) Binding Protein, Cytoplasmic 1 Antikörper

  1. Cow (Bovine) Monoclonal PABPC1 Primary Antibody für CyTOF, ELISA - ABIN267505 : Lee, Bedford: PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays. in EMBO reports 2002 (PubMed)
    Show all 7 Pubmed References

  2. Chicken Monoclonal PABPC1 Primary Antibody für ICC, FACS - ABIN108538 : Görlach, Burd, Dreyfuss: The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity. in Experimental cell research 1994 (PubMed)
    Show all 3 Pubmed References

  3. Chicken Monoclonal PABPC1 Primary Antibody für ICC, FACS - ABIN108539 : Gorgoni, Richardson, Burgess, Anderson, Wilkie, Gautier, Martins, Brook, Sheets, Gray: Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal PABPC1 Primary Antibody für IF, WB - ABIN525792 : Higashi, Tomigahara, Shiraki, Miyata, Mikami, Kimura, Moro, Inagaki, Kaneko: A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice. in The Journal of biological chemistry 2011 (PubMed)

Weitere Antikörper gegen Poly(A) Binding Protein, Cytoplasmic 1 Interaktionspartner

Human Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Interaktionspartner

  1. Data suggest that DEAD-box helicase 3 (DDX3X (zeige DDX3X Antikörper)) physically interacts and co-localizes with poly(A)-binding cytoplasmic protein (zeige BLZF1 Antikörper) 1 (PABPC1) and caprin-1 in lamellipodia at the leading edge of spreading cells; these interactions are dependent on mRNA; depletion of DDX3X (zeige DDX3X Antikörper) (via gene silencing with the CRISPR-Cas (zeige CSE1L Antikörper) system) leads to decreased cell motility. These studies were conducted using MRC5 lung fibroblast cell line.

  2. Data suggest that hnRNPLL (zeige HNRPLL Antikörper) specifically associates with cytoplasmic PABPC1 in both T-lymphocytes and plasma cells; PABPC1 promotes binding of hnRNPLL (zeige HNRPLL Antikörper) to immunoglobulin H (IgH, heavy chain) mRNA and regulates switching from mIgH (membrane isoform) to sIgH (secreted isoform) in plasma cells. (hnRNPLL (zeige HNRPLL Antikörper) = heterogeneous nuclear ribonucleoprotein L-like (zeige HNRPLL Antikörper) protein; PABPC1 = cytoplasmic poly[A]-binding protein 1)

  3. PABP enhances the productive binding of the eRF1 (zeige ZFP36L1 Antikörper)-eRF3 complex to the ribosome, via interactions with the N-terminal domain of eRF3a (zeige GSPT1 Antikörper) which itself has an active role in translation termination.

  4. Unr (zeige P2RY4 Antikörper) stimulated the binding of PABP1 to mRNA, and that Unr (zeige P2RY4 Antikörper) was required for the stable interaction of PABP1 and eIF4G (zeige EIF4G1 Antikörper) in cells.

  5. PABPC1 decreased expression in in infertile men with non-obstructive azoospermia

  6. BTG2 (zeige BTG2 Antikörper) stimulates mRNA deadenylation via CAF1 (zeige CHAF1B Antikörper) activation through interaction with PABPC1. Interaction of BTG2 (zeige BTG2 Antikörper) with the first RRM domain of PABPC1 is required for BTG2 (zeige BTG2 Antikörper) to control cell proliferation.

  7. PABPC1 is a novel co-regulator of the AR

  8. PABPC1 is upregulated in gastric carcinoma tissues, and high PABPC1 expression predicts poor survival. PABPC1 regulates proliferation and transformation of gastric cancer cells in vitro and in vivo. PABPC1 knockdown induces apoptosis.

  9. PABPC1 interacts with AGO2 (zeige EIF2C2 Antikörper) and is responsible for the microRNA mediated gene silencing in high grade hepatocellular carcinoma.

  10. Poly(A) binding protein 1 enhances cap-independent translation initiation of neurovirulence factor from avian herpesvirus

Mouse (Murine) Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Interaktionspartner

  1. Data suggest that hnRNPLL (zeige HNRPLL Antikörper) specifically associates with cytoplasmic PABPC1 in both T-lymphocytes and plasma cells; PABPC1 promotes binding of hnRNPLL (zeige HNRPLL Antikörper) to immunoglobulin H (IgH, heavy chain) mRNA and regulates switching from mIgH (membrane isoform) to sIgH (secreted isoform) in plasma cells. (hnRNPLL (zeige HNRPLL Antikörper) = heterogeneous nuclear ribonucleoprotein L-like (zeige HNRPLL Antikörper) protein; PABPC1 = cytoplasmic poly[A]-binding protein 1)

  2. Superovulation with low or high doses of gonadotropins significantly altered Epab and Pabpc1 mRNA levels in GV oocytes, MII oocytes and 1- and 2-cell embryos compared with their respective controls. These changes most likely lead to variations in expression of EPAB- and PABPC1-regulated genes, which may adversely influence the quality of oocytes and early embryos retrieved using superovulation.

  3. Data (including data from studies in knockout mice) suggest that Epab (embryonic poly(A)-binding protein), which is oocyte specific, is required for ability of cumulus cells and granulosa cells to exhibit responsiveness to Egf/Egfr (zeige EGFR Antikörper) signaling.

  4. Epab(-/-) oocytes are smaller in size, contain peripheral germinal vesicles, and are loosely associated with cumulus cells

  5. These findings suggest that EPAB may predominantly play roles in translational regulation of the mRNAs during early oogenesis and folliculogenesis, but PABPC1 most likely perform these roles in the later terms of ovarian development along with EPAB

  6. Epab is dispensable for mouse spermatogenesis and male fertility.

  7. We analyzed the expression of sperm-specific Akap3 (zeige AKAP3 Antikörper) and the potential regulatory factors of its protein synthesis during mouse spermiogenesis.

  8. Both Epab and Pabpc1 expression increase during early postnatal life and reach their peak at D32 testis.

  9. our data support the concept that expanded ATXN2 (zeige ATXN2 Antikörper) undergoes progressive insolubility and affects PABPC1 by a toxic gain-of-function mechanism with tissue-specific effects, which may be partially alleviated by the induction of FBXW8 (zeige FBXW8 Antikörper).

  10. EPAB is necessary for oogenesis, folliculogenesis and female fertility in mice.

Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antigen-Profil

Protein Überblick

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation\; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

Genbezeichner und Symbole assoziert mit PABPC1

  • poly(A) binding protein, cytoplasmic 1-like (pabpc1l) Antikörper
  • poly(A) binding protein, cytoplasmic 1 (pabpc1) Antikörper
  • poly(A) binding protein, cytoplasmic 1-like (PABPC1L) Antikörper
  • poly A binding protein, cytoplasmic 1 a (pabpc1a) Antikörper
  • poly(A) binding protein, cytoplasmic 1 (pabpc1-a) Antikörper
  • poly(A) binding protein, cytoplasmic 1 (PABPC1) Antikörper
  • poly(A) binding protein, cytoplasmic 1 (Pabpc1) Antikörper
  • ePAB Antikörper
  • fi20g03 Antikörper
  • pab-2 Antikörper
  • PAB1 Antikörper
  • Pabp Antikörper
  • Pabp1 Antikörper
  • pabpc1 Antikörper
  • PABPC2 Antikörper
  • PabpI Antikörper
  • Pabpl1 Antikörper
  • wu:fb16a02 Antikörper
  • wu:fi19b08 Antikörper
  • wu:fi20g03 Antikörper
  • wu:fj12d09 Antikörper
  • wu:fj61f06 Antikörper
  • zgc:55855 Antikörper
  • zgc:109879 Antikörper

Bezeichner auf Proteinebene für PABPC1

polyadenylate-binding protein 1-like , poly(A) binding protein, cytoplasmic 1 , polyadenylate-binding protein 1 , PABP 1-A , PABP-1-A , PABP-A , cytoplasmic poly(A)-binding protein 1-A , poly(A)-binding protein 1-A , polyadenylate-binding protein 1-A , xPABP1-A , poly(A) binding protein, cytoplasmic 2 , PABP 1 , PABP-1 , poly(A)-binding protein 1 , poly A binding protein 1

GENE ID SPEZIES
327625 Danio rerio
448595 Xenopus (Silurana) tropicalis
711882 Macaca mulatta
606498 Danio rerio
379896 Xenopus laevis
430997 Gallus gallus
26986 Homo sapiens
612751 Canis lupus familiaris
282296 Bos taurus
18458 Mus musculus
171350 Rattus norvegicus
Ausgewählte Anbieter für anti-Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) Antikörper
Haben Sie etwas anderes gesucht?