PABP Antikörper

Produktnummer ABIN108538

Produktdetails anti-PABP Antikörper

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Reaktivität: Human, Kaninchen, Huhn, Xenopus laevis, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PABP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: Protein G

Immunogen: Recombinant PABP (Human) expressed from its 1.85 kbp cDNA, NcoI to SspI

Klon: 10E10

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal antibody dilution should be determined by titration, however try:WB: Use at an assay dependent dilution. Detects a band of approximately 70 kDa (predicted molecular weight: 71 kDa)ICC/IF: Use at an assay dependent dilution. PubMed: 17977970Flow Cyt: Use 1 μg for 106 cells

Kommentare:

Myeloma, fusion partners: SP2/0

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Referenzen für anti-PABP Antikörper (ABIN108538)

Gorgoni, Richardson, Burgess, Anderson, Wilkie, Gautier, Martins, Brook, Sheets, Gray: "Poly(A)-binding proteins are functionally distinct and have essential roles during vertebrate development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 19, pp. 7844-9, (2011) (PubMed).

Unsworth, Raguz, Edwards, Higgins, Yagüe: "mRNA escape from stress granule sequestration is dictated by localization to the endoplasmic reticulum." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 9, pp. 3370-80, (2010) (PubMed).

Görlach, Burd, Dreyfuss: "The mRNA poly(A)-binding protein: localization, abundance, and RNA-binding specificity." in: Experimental cell research, Vol. 211, Issue 2, pp. 400-7, (1994) (PubMed).

Details zu PABP

Target: PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))

Andere Bezeichnung: PABP (PABPC1 Produkte)

Synonyme: PAB1 antikoerper, PABP antikoerper, PABP1 antikoerper, PABPC2 antikoerper, PABPL1 antikoerper, Pabp1 antikoerper, PabpI antikoerper, Pabpl1 antikoerper, ePAB antikoerper, Pabp antikoerper, pab1 antikoerper, pabp antikoerper, pabp1 antikoerper, pabpc1 antikoerper, pabpc2 antikoerper, PABPC1 antikoerper, wu:fb16a02 antikoerper, wu:fi19b08 antikoerper, wu:fj12d09 antikoerper, wu:fj61f06 antikoerper, zgc:109879 antikoerper, zgc:77608 antikoerper, poly(A) binding protein cytoplasmic 1 antikoerper, poly(A) binding protein, cytoplasmic 1 antikoerper, poly(A) binding protein, cytoplasmic 1 S homeolog antikoerper, poly(A) binding protein cytoplasmic 1 like antikoerper, poly(A) binding protein, cytoplasmic 1 L homeolog antikoerper, poly(A) binding protein, cytoplasmic 1a antikoerper, poly A binding protein, cytoplasmic 1 b antikoerper, PABPC1 antikoerper, Pabpc1 antikoerper, pabpc1.S antikoerper, pabpc1 antikoerper, PABPC1L antikoerper, pabpc1.L antikoerper, pabpc1a antikoerper, pabpc1b antikoerper

Hintergrund: Synonyms:
PAB 1 antibody,PAB1 antibody,PABP 1 antibody,PABP1 antibody,PABPC 1 antibody,PABPC1antibody,PABPC2 antibody,PABPL1 antibody,Poly A binding protein 1 antibody,Poly A binding protein cytoplasmic1 antibody,Polyadenylate binding protein 1 antibody

Gen-ID: 117282

OMIM: 604679

UniProt: P22626

Pathways: SARS-CoV-2 Protein Interaktom