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PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen PIWIL4 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal PIWIL4 Primary Antibody für FACS, IHC - ABIN1724794
Gu, Ji, Shi, Long, Xia, Song, Wang, Wang: Genetic variants in Piwi-interacting RNA pathway genes confer susceptibility to spermatogenic failure in a Chinese population. in Human reproduction (Oxford, England) 2010
Zeige alle 2 Referenzen für 1724794
Human Polyclonal PIWIL4 Primary Antibody für WB - ABIN2785170
Sugimoto, Kage, Aki, Sano, Kitagawa, Nagase, Yatomi, Ohishi, Takai: The induction of H3K9 methylation by PIWIL4 at the p16Ink4a locus. in Biochemical and biophysical research communications 2007
Human Polyclonal PIWIL4 Primary Antibody für ICC, IF - ABIN4345779
Cordeiro, Navarro, Gaya, Díaz-Beyá, Gonzalez-Farré, Castellano, Fuster, Martínez, Martínez, Monzó: PiwiRNA-651 as marker of treatment response and survival in classical Hodgkin lymphoma. in Oncotarget 2016
PIWIL2 (zeige PIWIL2 Antikörper) and PIWIL4 genes expression in synovial fibroblasts of the rheumatoid arthritis patients.PIWIL4 does not regulate methylation or expression of LINE-1.
MiR (zeige MLXIP Antikörper)-384 functioned as tumor suppressor by decreasing PIWIL4 in glioma cell lines.
study demonstrates the presence of PIWI (zeige PIWIL1 Antikörper)-like proteins in somatic cells and the possible role of HIWI2 in preserving the functional integrity of epithelial cells probably by modulating the phosphorylation status of Akt (zeige AKT1 Antikörper).
PIWIL4 is highly expressed in both breast cancer tissues and the cytoplasm of MDA-MB-231 cells derived from breast cancer. Reducing PIWIL4 expression drastically impairs the migration ability of MDA-MB-231 cells, significantly increases their apoptosis, and mildly affects their proliferation.
Results show that three CpG loci within FYN (zeige FYN Antikörper) were hypermethylated in obese individuals, while obesity was associated with lower methylation of CpG loci within PIWIL4 and TAOK3 (zeige TAOK3 Antikörper).
study to evaluate frequency of PIWIL4 genetic variants in order to better define the relationship between PIWIL4 SNPs and defective spermatogenesis and specific spermatogenic disorders; results suggest genetic and epigenetic alterations that affect the PIWI pathway contribute to unsuccessful sperm production
Data suggest that MIWI2 and MIWI2-associated piRNAs have functions beyond TE suppression.
associations were determined between the Piwi-like family member expression levels and clinicopathological parameters of ccRCC, suggesting a potential role for these genes/proteins in ccRCC diagnostics and tumorigenesis
we identified a significant association between the expression of Piwi-like 2 (zeige PIWIL2 Antikörper) and 4 mRNAs and the tumor-specific survival of soft tissue sarcoma patients.
PIWIL4 might play an oncogenic role in cervical cancer
Miwi2 deficiency had only a minor impact on piRNA biogenesis. Miwi2-knockout mice indicated overexpression of several LINE1 TE families.
piRNA biogenesis triggered by PIWI slicing, and promoted by EXD1, ensures that the same guides instruct PIWI proteins in the nucleus and cytoplasm.
MIWI2 is not solely necessary for hematopoiesis within the normal life span of a mouse.
Mice with a global deletion of all three piwi (zeige PIWIL1 Antikörper) genes, Miwi (zeige PIWIL1 Antikörper), Mili (zeige PIWIL2 Antikörper), and Miwi2, are able to maintain long-term hematopoiesis with no observable effect on the homeostatic hematopoietic stem cells compartment in adult mice.
Icariin induced a decrease in piwil4 protein expression and piwil4 silencing significantly enhanced the cytotoxic effects of icariin in MLTC-1 cells.
Results identify TDRD9 as a functional partner of MIWI2 and indicate that the tudor-piwi association is a conserved feature, while two separate axes, TDRD9-MIWI2 and TDRD1-MILI, cooperate in the piwi-small RNA pathway in the mouse male germline.
Data strongly suggest that MILI (zeige PIWIL2 Antikörper) and MIWI2 play essential roles in establishing de novo DNA methylation (zeige HELLS Antikörper) of retrotransposons in fetal male germ cells.
purified the three murine Piwi (zeige PIWIL1 Antikörper) family proteins, MILI (zeige PIWIL2 Antikörper), MIWI (zeige PIWIL1 Antikörper), and MIWI2, from mouse germ cells and characterized their interacting protein partners
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003
, piwi-like protein 4
, piwi-like homolog 4