PIWIL4 Antikörper

Produktnummer ABIN7256712

Produktdetails anti-PIWIL4 Antikörper

Target: PIWIL4 (Piwi-Like 4 (PIWIL4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIWIL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human PIWIL4 (NP_689644.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PIWIL4

Target: PIWIL4 (Piwi-Like 4 (PIWIL4))

Andere Bezeichnung: PIWIL4 (PIWIL4 Produkte)

Synonyme: HIWI2 antikoerper, MIWI2 antikoerper, 9230101H05Rik antikoerper, Miwi2 antikoerper, piwi like RNA-mediated gene silencing 4 antikoerper, piwi-like RNA-mediated gene silencing 4 antikoerper, PIWIL4 antikoerper, Piwil4 antikoerper

Hintergrund: PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.

Molekulargewicht:

Observed_MW: 105 kDa

Calculated_MW: 52 kDa/56 kDa/96 kDa

Gen-ID: 143689

UniProt: Q7Z3Z4