anti-Phosducin-Like (PDCL) Antikörper

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. Zusätzlich bieten wir Ihnen Phosducin-Like Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PDCL 5082 Q13371
PDCL 64013 Q63737
PDCL 67466 Q9DBX2
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Top anti-Phosducin-Like Antikörper auf antikoerper-online.de

Showing 10 out of 43 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB IHC-P Image PHLP antibody detects PHLP protein at cytoplasm on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. PHLP antibody , dilution: 1:500. ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PHLP, antibody at 1:200 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PDCL Antibody [NBP1-85079] - Staining of human cell line U-251 MG shows positivity in cytoplasm. Immunohistochemistry-Paraffin: PDCL Antibody [NBP1-85079] - Staining of human skeletal muscle shows distinct cytoplasmic positivity in myocytes. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: PDCL Antibody [NBP1-32523] - Paraformaldehyde-fixed HeLa, using antibody at 1:200 dilution. Western Blot: PDCL Antibody [NBP1-32523] - Sample(30 ug whole cell lysate)A:H129910% SDS PAGE, antibody diluted at 1:3000. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti PHLP Polyclonal Antibody,Unconjugated (ABIN715121) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: rat brain lysates Lane 2: rat kidney lysates probed with Anti PHLP Polyclonal Antibody, Unconjugated (ABIN715121) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 85kD. Observed band size: 85kD. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

PDCL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Phosducin-Like Antikörper

  1. Human Polyclonal PDCL Primary Antibody für WB - ABIN1944777 : Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ... in Genome research 2001 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal PDCL Primary Antibody für ICC, IF - ABIN4344392 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen Phosducin-Like Interaktionspartner

Human Phosducin-Like (PDCL) Interaktionspartner

  1. PhLP1 binding stabilizes the Gbeta (zeige SUCLG2 Antikörper) fold, disrupting interactions with CCT (zeige FLVCR2 Antikörper) and releasing a PhLP1-Gbeta (zeige SUCLG2 Antikörper) dimer for assembly with Ggamma.

  2. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins.

  3. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 (zeige CSNK2A1 Antikörper) and alternative splicing of the regulator

  4. the strong inhibitory action of PhLP(S) on Gbetagamma signaling is the result of a previously unrecognized mechanism of Gbetagamma-regulation, inhibition of Gbetagamma-folding by interference with TCP-1alpha (zeige TCP1 Antikörper)

  5. PhLP phosphorylation permits the release of a PhLP x Gbeta (zeige SUCLG2 Antikörper) intermediate from cytosolic chaperonin (zeige HSPD1 Antikörper) complex, allowing Ggamma to associate with Gbeta (zeige SUCLG2 Antikörper) in this intermediate complex.

  6. cytosolic chaperonin complex-dependent mechanism exists for Gbeta5-RGS7 assembly that utilizes the co-chaperone activity of PhLP1 in a unique way

  7. PhLP-M1-G149, a Gbetagamma-interacting construct derived from phosducin-like protein 1 (PhLP) is a differential inhibitor of Gbetagamma

Mouse (Murine) Phosducin-Like (PDCL) Interaktionspartner

  1. findings reveal a common mechanism of Gbetagamma and RGS9-Gbeta5 assembly in rods and cones, highlighting the importance of PhLP1 and CCT-mediated Gbeta complex formation in G protein signaling.

  2. evidence of a generic mechanism, whereby the splicing of the PhLP gene could potentially and efficiently regulate the cellular levels of heterotrimeric G proteins.

  3. this study demonstrated in vivo that PhLP1 is required for the folding and assembly of both Gbetagamma and Gbeta5 (zeige GNB5 Antikörper)-RGS9 (zeige RGS Antikörper).

  4. These data are consistent with the hypothesis that PhLP is a widely expressed modulator of Gbetagamma function.

  5. These results suggest a mechanism for Gbetagamma assembly in which PhLP stabilizes the nascent Gbeta (zeige SUCLG2 Antikörper) polypeptide until Ggamma can associate, resulting in membrane binding of Gbetagamma and release of PhLP to catalyze another round of assembly.

  6. N-glycosylated phosducin-like protein long (PhLP(L)) is expressed in all structures of the central nervous system and regulates opioid receptor function in the brain.

  7. identification of novel germ-like specific form in phosducin-like protein family

  8. physiological control of G-protein regulation by PhLP seems to involve phosphorylation by CK2 (zeige CSNK2A1 Antikörper) and alternative splicing of the regulator

Cow (Bovine) Phosducin-Like (PDCL) Interaktionspartner

  1. antagonistic actions of PhLP3 and prefoldin serve to modulate CCT activity and play a key role in establishing a functional cytoskeleton in vivo

Phosducin-Like (PDCL) Antigen-Profil

Protein Überblick

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins.

Genbezeichner und Symbole assoziert mit anti-Phosducin-Like (PDCL) Antikörper

  • phosducin like (PDCL) Antikörper
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  • phosducin like (pdcl) Antikörper
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  • im:6793474 Antikörper
  • Phlp Antikörper
  • PhLP1 Antikörper
  • wu:fc06a08 Antikörper
  • zgc:73264 Antikörper

Bezeichner auf Proteinebene für anti-Phosducin-Like (PDCL) Antikörper

phosducin-like protein , PHLP , phosducin-like

GENE ID SPEZIES
5082 Homo sapiens
64013 Rattus norvegicus
67466 Mus musculus
548824 Xenopus (Silurana) tropicalis
286773 Bos taurus
323645 Danio rerio
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