anti-Palmitoyl-Protein Thioesterase 1 (PPT1) Antikörper

The protein encoded by PPT1 is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. Zusätzlich bieten wir Ihnen PPT1 Proteine (14) und PPT1 Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PPT1 5538 P50897
PPT1 19063 O88531
PPT1 29411 P45479
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Top anti-PPT1 Antikörper auf antikoerper-online.de

Showing 10 out of 94 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
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Human Kaninchen Unkonjugiert IHC (p), WB IHC(P): Human Intestinal Cancer Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Maus Unkonjugiert WB 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: PPT1 Antibody [NBP1-85563] - Staining of human cerebellum shows strong cytoplasmic positivity. Western Blot: PPT1 Antibody [NBP1-85563] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-PPT1 Polyclonal Antibody, Unconjugated (ABIN718946) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse brain labeled with Anti-PPT1 Polyclonal Antibody, Unconjugated (ABIN718946) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of hPPT1-C46 (ABIN389116) in mouse cerebellum tissue lysates (35 µg/lane).PPT1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of PPT1 Antibody (C-term) (ABIN389117) in 293 cell line lysates (35 µg/lane). PPT1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with PPT1 antibody (C-term) (ABIN389117), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
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PPT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PPT1 Antikörper

  1. Human Monoclonal PPT1 Primary Antibody für WB - ABIN1944801 : Crews, Lane, Schreiber: Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal PPT1 Primary Antibody für IHC, IHC (p) - ABIN4347151 : Scifo, Szwajda, Soliymani, Pezzini, Bianchi, Dapkunas, Dębski, Uusi-Rauva, Dadlez, Gingras, Tyynelä, Simonati, Jalanko, Baumann, Lalowski: Quantitative analysis of PPT1 interactome in human neuroblastoma cells. in Data in brief 2015 (PubMed)

Weitere Antikörper gegen PPT1 Interaktionspartner

Human Palmitoyl-Protein Thioesterase 1 (PPT1) Interaktionspartner

  1. Proteomics analysis on isolated cilia revealed 660 proteins, which differed in their abundance levels between wild type and Ppt1 knock out.

  2. we reveal the existence of a positive feedback loop, where palmitoylation of PPT1 results in decreased activity and subsequent elevation in the amount of palmitoylated proteins.

  3. analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma (zeige ARHGEF16 Antikörper) cells

  4. Data (including data from knockout mice) suggest that deficiency of PPT1 leads to accumulation of granular osmiophilic deposits in many cell types, especially in astrocytes. [review-like article]

  5. Data suggest that human monocytes and macrophages express PPT1; PPT1 appears to contribute 32-40% of 2-arachidonylglycerol hydrolysis activity in THP1 monocyte cell line.

  6. This neuroimaging finding in PPT1-related neuronal ceroid lipofuscinosis (zeige CLN6 Antikörper) was not previously reported.

  7. Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis in cultured cells from Infantile neuronal ceroid lipofuscinosis (zeige CLN6 Antikörper) patients.

  8. Results describe the correlation between the three-dimensional structural changes in mutant palmitoyl protein thioesterase 1 and biochemical phenotypes.

  9. mutated in neuronal ceroid lipofuscinosis (zeige CLN6 Antikörper)

  10. The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2.

Mouse (Murine) Palmitoyl-Protein Thioesterase 1 (PPT1) Interaktionspartner

  1. Proteomics analysis on isolated cilia revealed 660 proteins, which differed in their abundance levels between wild type and Ppt1 knock out.

  2. In the novel Cln1(R151X) mouse model of INCL.

  3. Parkinson-like motor/sensorimotor deficits in Cln1-/- mice are not mediated by dopamine deficiency.

  4. Data show that Cln1 mutations disrupt the maturation of cathepsin D (zeige CTSD Antikörper) in lysosome contributing to neuropathology of infantile neuronal ceroid lipofuscinoses and suggest cathepsin D (zeige CTSD Antikörper) deficiency to be common link between infantile and congenital form.

  5. The authors have generated a Cln1 R151X point mutation mouse model that recapitulates the molecular, neuropathological and behavioral phenotypes of neuronal ceroid lipofuscinoses.

  6. Data (including data from knockout mice) suggest that deficiency of Ppt1 leads to accumulation of granular osmiophilic deposits in many cell types, especially in astrocytes. [review-like article]

  7. Data suggest that mouse macrophages express PPT1; PPT1 appears to contribute to 2-arachidonylglycerol hydrolysis activity in peritoneal macrophages in culture.

  8. The simultaneous loss of both Cln1 and Cln5 (zeige CLN5 Antikörper) genes might enhance the typical pathological phenotypes of these mice by disrupting or downregulating shared or convergent pathogenic pathways.

  9. These results uncover a previously unknown phenotype associated with PPT1 deficiency, that of altered thermoregulation, which is associated with impaired lipolysis and neurotransmitter release to brown adipose tissue during cold exposure.

  10. The addition of the small molecule PPT1 mimetic can further increase that response.

PPT1 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit PPT1

  • palmitoyl-protein thioesterase 1 (MGYG_00692) Antikörper
  • palmitoyl-protein thioesterase 1 (PPT1) Antikörper
  • palmitoyl-protein thioesterase 1 (Ppt1) Antikörper
  • Protein PPT-1 (ppt-1) Antikörper
  • similar to palmitoyl-protein thioesterase (RGD1560700) Antikörper
  • 9530043G02Rik Antikörper
  • AA960502 Antikörper
  • C77813 Antikörper
  • CLN1 Antikörper
  • D4Ertd184e Antikörper
  • INCL Antikörper
  • Ppt Antikörper

Bezeichner auf Proteinebene für PPT1

palmitoyl-protein thioesterase 1 , ceroid-palmitoyl-palmitoyl-protein thioesterase 1 , palmitoyl-protein hydrolase 1 , PPT-1 , palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) , palmitoyl protein thioesterase

GENE ID SPEZIES
10031925 Arthroderma gypseum CBS 118893
5538 Homo sapiens
19063 Mus musculus
29411 Rattus norvegicus
419681 Gallus gallus
475316 Canis lupus familiaris
281421 Bos taurus
191744 Caenorhabditis elegans
362585 Rattus norvegicus
Ausgewählte Anbieter für anti-PPT1 (PPT1) Antikörper
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