PPT1 Antikörper (AA 1-306)

Produktnummer ABIN1944801

Zitiert in 3+ Publikationen. Der Maus Monoklonal anti-PPT1 Antikörper (Klon 1117CT11-2-1-4) (ABIN1944801) detektiert spezifisch PPT1 in WB, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PPT1 Antikörper (AA 1-306) (ABIN1944801)

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 1117CT11-2-1-4

Produktdetails anti-PPT1 Antikörper

Bindungsspezifität: AA 1-306

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This PPT1 antibody is generated from a mouse immunized with a full-length recombinant protein from human PPT1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. FC: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-PPT1 Antikörper (ABIN1944801)

Crews, Lane, Schreiber: "Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 9, pp. 4316-9, (1996) (PubMed).

Schriner, Yi, Hofmann: "cDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis." in: Genomics, Vol. 34, Issue 3, pp. 317-22, (1996) (PubMed).

Vesa, Hellsten, Verkruyse, Camp, Rapola, Santavuori, Hofmann, Peltonen: "Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis." in: Nature, Vol. 376, Issue 6541, pp. 584-7, (1995) (PubMed).

Details zu PPT1

Target: PPT1 (Palmitoyl-Protein Thioesterase 1 (PPT1))

Andere Bezeichnung: PPT1

Hintergrund: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.

Molekulargewicht: 34193

Gen-ID: 5538

UniProt: P50897

Pathways: SARS-CoV-2 Protein Interaktom