Nicotinamide Nucleotide Adenylyltransferase 3 Proteine (NMNAT3)

NMNAT3 encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. Zusätzlich bieten wir Ihnen NMNAT3 Antikörper (71) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte NMNAT3 NMNAT3 363118  
NMNAT3 349565 Q96T66
NMNAT3 74080 Q99JR6
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
1.001,06 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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NMNAT3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
,
Mouse (Murine)

Weitere Proteine zu Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) Interaktionspartnern

Human Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) Interaktionspartner

  1. NMNAT3 is absent in mitochondria in human cells, and, akin to plants and yeast, cytosolic NAD maintains the mitochondrial NAD pool.

  2. Red blood cells represent the first human cell type with a remarkable predominance of NMNAT3 over NMNAT1 (zeige NMNAT1 Proteine); NMNAT2 (zeige NMNAT2 Proteine) is absent.

  3. NMNAT1 (zeige NMNAT1 Proteine) is a nuclear protein (zeige RDBP Proteine), whereas NMNAT2 (zeige NMNAT2 Proteine) and -3 are localized to the Golgi complex and the mitochondria

  4. NMN (zeige NTS Proteine) binds before ATP with the mitochondrial isozyme NMNAT3. Only NMNAT3 utilizes ITP (zeige ITPA Proteine) efficiently in place of ATP, and NMNH conversion to NADH by NMNAT1 (zeige NMNAT1 Proteine) and NMNAT3 occurs at similar rates.

Mouse (Murine) Nicotinamide Nucleotide Adenylyltransferase 3 (NMNAT3) Interaktionspartner

  1. NMNAT3 regulates the activity of SIRT3 (zeige SIRT3 Proteine) via synthesis of mitochondria NAD.

  2. Results indicated that Nmnat3 is dispensable in the maintenance of mitochondrial NAD levels, and that other NAD regulatory pathways may exist in mitochondria.

  3. Data indicate that nicotinamide mononucleotide adenylyltransferase 3 (Nmnat3)deficiency causes splenomegaly and hemolytic anemia in mice.

  4. results suggest that axonal protection by NMNAT (zeige NMNAT1 Proteine) expression in neurons is provided by modifying mitochondrial functionNMNAT activity does lead to axonal protection phenotype in vivo

NMNAT3 Protein Überblick

Protein Überblick

This gene encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. These enzymes use ATP to catalyze the synthesis of nicotinamide adenine dinucleotide or nicotinic acid adenine dinucleotide from nicotinamide mononucleotide or nicotinic acid mononucleotide, respectively. The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit NMNAT3

  • nicotinamide nucleotide adenylyltransferase 3 (Nmnat3)
  • nicotinamide nucleotide adenylyltransferase 3 (NMNAT3)
  • novel protein similar to vertebrate nicotinamide nucleotide adenylyltransferase protein family (nmnat3)
  • 4933408N02Rik Protein
  • PNAT-3 Protein
  • PNAT3 Protein

Bezeichner auf Proteinebene für NMNAT3

nicotinamide mononucleotide adenylyltransferase 3 , nicotinamide nucleotide adenylyltransferase 3 , NMN adenylyltransferase 3 , NaMN adenylyltransferase 3 , nicotinate-nucleotide adenylyltransferase 3 , pyridine nucleotide adenylyltransferase 3 , naMN adenylyltransferase 1 , nicotinate-nucleotide adenylyltransferase 1

GENE ID SPEZIES
363118 Rattus norvegicus
424820 Gallus gallus
460735 Pan troglodytes
572070 Danio rerio
715614 Macaca mulatta
349565 Homo sapiens
74080 Mus musculus
477091 Canis lupus familiaris
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