anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antikörper

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Zusätzlich bieten wir Ihnen Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Ratte MLL1 MLL1 315606  
MLL1 214162 P55200
MLL1    
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Top anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Antikörper auf antikoerper-online.de

Showing 10 out of 10 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert DB Dot blot analysis of Phospho-TJP2-S978 Antibody Phospho-specific Pab  on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$265.00
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Human Kaninchen Unkonjugiert ELISA   200 μL Anmelden zum Anzeigen 11 bis 16 Tage
$594.00
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Human Kaninchen APC ELISA   200 μL Anmelden zum Anzeigen 16 Days
$743.29
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Human Kaninchen FITC ELISA   200 μL Anmelden zum Anzeigen 16 Days
$743.29
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Human Kaninchen HRP ELISA   200 μL Anmelden zum Anzeigen 16 Days
$743.29
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Human Kaninchen PE ELISA   200 μL Anmelden zum Anzeigen 16 Days
$743.29
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Human Kaninchen Alkaline Phosphatase (AP) ELISA   200 μL Anmelden zum Anzeigen 16 Days
$743.29
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Human Kaninchen Biotin ELISA   200 μL Anmelden zum Anzeigen 16 Days
$743.29
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Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$510.36
Details

MLL1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


Human , ,


, , , , ,

Weitere Antikörper gegen Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 Interaktionspartner

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Interaktionspartner

  1. Epigenomic profiling indicates an abnormal H3K79me2 pattern on MLL (zeige MLL Antikörper)-fusion targeted genes, but the molecular mechanism underlying this epigenetic dependency is not well understood.

  2. NUP98 (zeige NUP98 Antikörper)-HOXA9 (zeige HOXA9 Antikörper) interacts with MLL (zeige MLL Antikörper) via the NUP98 (zeige NUP98 Antikörper) second FG repeat domain. In the absence of MLL (zeige MLL Antikörper) (in knockout mice), NUP98 (zeige NUP98 Antikörper)-HOXA9 (zeige HOXA9 Antikörper)-induced cell immortalization and leukemogenesis are severely inhibited. MLL (zeige MLL Antikörper) is important for the recruitment of NUP98 (zeige NUP98 Antikörper)-HOXA9 (zeige HOXA9 Antikörper) to the HOXA locus and for NUP98 (zeige NUP98 Antikörper)-HOXA9 (zeige HOXA9 Antikörper)-induced HOXA gene expression. MLL (zeige MLL Antikörper) is crucial for NUP98 (zeige NUP98 Antikörper)-HOXA9 (zeige HOXA9 Antikörper) leukemia initiation.

  3. Atg5 (zeige ATG5 Antikörper)-dependent autophagy contributes to the development of acute myeloid leukemia (zeige BCL11A Antikörper) in an MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper)-driven mouse model.

  4. These results reveal a cooperative transcriptional activation mechanism of AEP (zeige LGMN Antikörper) and DOT1L (zeige DOT1L Antikörper) and suggest a molecular rationale for the simultaneous inhibition of the MLL (zeige MLL Antikörper) fusion-AF4 complex and DOT1L (zeige DOT1L Antikörper) for more effective treatment of MLL (zeige MLL Antikörper)-rearranged leukemia.

  5. This study demonstrated that Kmt2a (zeige MLL Antikörper) regulates synaptic plasticity in striatal neurons and provides an epigenetic drug target for anxiety and dopamine-mediated behaviors.

  6. Inactivation of Kmt2a in Men1-deficient mice accelerated pancreatic islet tumorigenesis and shortened the average life span. Increases in cell proliferation were observed in mouse pancreatic islet tumors upon inactivation of both Kmt2a and Men1.

  7. Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway.

  8. HoxBlinc RNA Recruits Set1 (zeige SETD1A Antikörper)/MLL (zeige MLL Antikörper) Complexes to Activate Hox (zeige MSH2 Antikörper) Gene Expression Patterns and Mesoderm Lineage Development.

  9. MLL1 and DOT1L (zeige DOT1L Antikörper) cooperate with meningioma-1 to induce acute myeloid leukemia (zeige BCL11A Antikörper).

  10. Set1 (zeige SETD1A Antikörper) role in cellular reprogramming and its interactions with Dpy30 (zeige DPY30 Antikörper),Myc (zeige MYC Antikörper),Sox2 (zeige SOX2 Antikörper) and Ash2l (zeige ASH2L Antikörper) reprogramming factors

Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1) Antigen-Profil

Protein Überblick

Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation. Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity. Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9'. Required for transcriptional activation of HOXA9. Promotes PPP1R15A-induced apoptosis (By similarity).

Genbezeichner und Symbole assoziert mit MLL1

  • lysine methyltransferase 2A (Kmt2a) Antikörper
  • lysine (K)-specific methyltransferase 2A (Kmt2a) Antikörper
  • 6430520K01 Antikörper
  • ALL-1 Antikörper
  • All1 Antikörper
  • Cxxc7 Antikörper
  • HRX Antikörper
  • HTRX1 Antikörper
  • mKIAA4050 Antikörper
  • Mll Antikörper
  • Mll1 Antikörper

Bezeichner auf Proteinebene für MLL1

Mixed-lineage leukemia (also acute lymphocytic leukemia 1 or tritorax Drosophila gene) , histone-lysine N-methyltransferase MLL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) , myeloid/lymphoid or mixed-lineage leukemia 1 , histone-lysine N-methyltransferase 2A , lysine N-methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia protein 1 , trithorax Drosophila , zinc finger protein HRX

GENE ID SPEZIES
315606 Rattus norvegicus
214162 Mus musculus
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