MLL1 Antikörper

Produktnummer ABIN6952424

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MLL1 in ChIP, ELISA und ChIP-seq. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MLL1 Antikörper (ABIN6952424)

Target: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLL1 Antikörper ist unkonjugiert

Applikation: Chromatin Immunoprecipitation (ChIP), ELISA, ChIP DNA-Sequencing (ChIP-seq)

Güteklasse: ChIP-seq Grade

Produktdetails anti-MLL1 Antikörper

Spezifität: Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.

Aufreinigung: whole antiserum

Immunogen: synthetic peptide

Anwendungsinformationen

Applikationshinweise: ChIP/ChIP-seq 2 μL:ChIP
ELISA 1:100 - 1:1,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: serum, 0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu MLL1

Target: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Andere Bezeichnung: MLL1

Hintergrund: MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.

UniProt: Q03164