anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) Antikörper

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP12 Kits (64) und MMP12 Proteine (31) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MMP12 17381 P34960
MMP12 117033 Q63341
MMP12 4321 P39900
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Top anti-MMP12 Antikörper auf antikoerper-online.de

Showing 10 out of 196 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen Unkonjugiert ELISA, WB Observed bind size: 55KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of MMP-12 expression in mouse small intestine tissue lysate. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of anti-hMMP12-R406 Pab (ABIN390136) pre-incubated without(lane 1) and with(lane 2) blocking peptide in 293 cell line lysate. MMP12(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Western blot analysis of anti-hMMP12-R406 Pab (ABIN390136) pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse kidney tissue lysates. MMP12(arrow) was detected using the purified polyclonal antibody (1:60 dilution). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, treated with etoposide 25uM 1h, using MMP12 (Cleaved-Glu106) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB Anti-MMP12 antibody, Western blotting Lane 1: SMMC Cell Lysate Lane 2: HEPA Cell Lysate Lane 3: HELA Cell Lysate Lane 4: K562 Cell Lysate Lane 5: MCF-7 Cell Lysate 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung Cancer, antibody was diluted at 1:100. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: MMP-12 Antibody [NBP1-52011] - Analysis of MMP-12 in Human Breast Cancer lysate (35ug protein in RIPA buffer) using NBP1-52011 at 0.5 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse ovarian tissue labeled with Anti-MMP-12, Unconjugated (ABIN735413) followed by conjugation to the secondary antibody 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$318.45
Details

MMP12 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-MMP12 Antikörper

  1. Human Monoclonal MMP12 Primary Antibody für ELISA (Capture), ELISA - ABIN786701 : Chaudhuri, McSharry, Brady, Donnelly, Grierson, McGuinness, Jolly, Weir, Messow, Spears, Miele, Nocka, Crowther, Thompson, Brannigan, Lafferty, Sproule, Macnee, Connell, Murchison, Shepherd et al.: Sputum matrix metalloproteinase-12 in patients with chronic obstructive pulmonary disease and asthma: relationship to disease severity. ... in The Journal of allergy and clinical immunology 2012 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MMP12 Primary Antibody für IF, IHC (p) - ABIN390136 : Shapiro, Kobayashi, Ley: Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. in The Journal of biological chemistry 1993 (PubMed)
    Show all 3 Pubmed References

  3. Human Monoclonal MMP12 Primary Antibody für ELISA (Detection), IHC (fro) - ABIN786697 : Souissi, Billiet, Cuaz-Pérolin, Slimane, Rouis: Matrix metalloproteinase-12 gene regulation by a PPAR alpha agonist in human monocyte-derived macrophages. in Experimental cell research 2008 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal MMP12 Primary Antibody für IHC, WB - ABIN223402 : Ikonomidis, Jones, Barbour, Stroud, Clark, Kaplan, Zeeshan, Bavaria, Gorman, Spinale, Gorman: Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves. in The Journal of thoracic and cardiovascular surgery 2007 (PubMed)

  5. Human Polyclonal MMP12 Primary Antibody für ELISA, WB - ABIN4334937 : Mirowska-Guzel, Gromadzka, Czlonkowski, Czlonkowska: Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population. in Journal of neuroimmunology 2009 (PubMed)

Weitere Antikörper gegen MMP12 Interaktionspartner

Mouse (Murine) Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) Interaktionspartner

  1. findings define a novel physiological function of Shp2 (zeige PTPN11 Antikörper) in TGF-beta1 (zeige TGFB1 Antikörper)/MMP12-dependent emphysema, adding insights into potential etiologies for this chronic lung disorder.

  2. Mmp12 is expressed early following corneal epithelial injury with highest expression levels at 8 h after injury and lower expression levels at 4 and 8 days after injury. We investigated whether MMP12 has an effect on the rate of epithelial repair and cell migration using in vivo and in vitro scratch assays performed on WT and Mmp12(-/-) mice

  3. MMP-12 produced by macrophages infiltrating into glomeruli contributed to the degradation of collagen type IV (zeige COL4 Antikörper) and fibronectin (zeige FN1 Antikörper).

  4. MMP12 causes arterial stiffening in mice and suggest that it functions similarly in humans.

  5. These results suggest that MMP-12 production during emphysema exacerbation results in increased mortality and disease progression.

  6. study found significant increases of MMP-3 (zeige MMP3 Antikörper) and MMP-12 mRNA levels and MMP12 zymographic activities in response to Cryptococcus neoformans infection but not C. gattii infection

  7. The results suggest that pulmonary C fiber involvement in long-term airway inflammation and airway hyperresponsiveness occurred at least partially via modulating MMP-12, and the activation of PAR2 (zeige F2RL1 Antikörper) might be related to MMP-12 production.

  8. MMP-12 up-regulation mediated by SARM (zeige SARM1 Antikörper)-TRIF (zeige RNF138 Antikörper) signaling pathway contributes to IFN-gamma (zeige IFNG Antikörper)-independent airway inflammation and AHR (zeige AHR Antikörper) post RSV infection in nude mice.

  9. MMP-12 and MMP-13 (zeige MMP13 Antikörper) alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  10. Post-MI, MMP-12i impaired CD44 (zeige CD44 Antikörper)-HA interactions to suppress neutrophil apoptosis and prolong inflammation, which worsened LV function.

Human Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) Interaktionspartner

  1. G allele of MMP12 -82 A > G promoter polymorphism as a protective factor for COPD (zeige ARCN1 Antikörper) in Bulgarian population

  2. Data indicate that MMP1 (zeige MMP1 Antikörper), MMP12 and PPARG (zeige PPARG Antikörper) and hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-31-5p, hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-224-5p, and hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-223-3p were able to distinguish tumors from NPT with high sensitivity and specificity.

  3. Increased levels of MMP1 (zeige MMP1 Antikörper) and MMP12 on tumor-associated macrophages in the peripheral areas of dermatofibrosarcoma protuberance might contribute to local invasion

  4. Matrix metalloprotease (MMP) regulation was the top pathway involved in gingival aging. MMP3 (zeige MMP3 Antikörper), MMP9 (zeige MMP9 Antikörper), MMP12, and MMP13 (zeige MMP13 Antikörper) were upregulated in old gingival tissues, concomitantly with interleukin-1 beta (IL1B (zeige IL1B Antikörper)) expression.

  5. We also found that MMP12 facilitated type I collagen induced platelet aggregation, adhesion and alpha granule secretion. Similarly, one short peptide, WYKG, facilitated type I collagen induced platelet alpha granule secretion. We conclude that platelet express MMP12 may facilitate platelet activation through shedding of CEACAM1 (zeige CEACAM1 Antikörper).

  6. There were no statistically significant differences in the distribution of MMP7 (zeige MMP7 Antikörper) -181 A/G and MMP12 -82 A/G genotype, allele, or haplotype frequencies between IRSA patients and controls, as well as patients' primary and secondary idiopathic recurrent spontaneous abortion

  7. To conclude, Pseudomonas aeruginosa infection induced the expression of matrix metalloproteinases, and Pseudomonas aeruginosa type III secretion system appeared to be a key player in MMP-12 and MMP-13 (zeige MMP13 Antikörper) expression, which is further controlled by NF-kappaB (zeige NFKB1 Antikörper) signaling.

  8. This study demonstrated that the MMP-12 levels was significantly higher in patients with atheromatous plaques than in those without plaques.

  9. High MMP12 expression is associated with gastric cancer.

  10. Study evaluated MMP-12 and TIMP-1 (zeige TIMP1 Antikörper), TIMP-2 (zeige TIMP2 Antikörper), TIMP-3 (zeige TIMP3 Antikörper), and TIMP-4 (zeige TIMP4 Antikörper) levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (zeige CSE1L Antikörper)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 is related to critical CAS (zeige CSE1L Antikörper) independently on symptoms, moreover, TIMP-3 (zeige TIMP3 Antikörper) and TIMP-4 (zeige TIMP4 Antikörper) seem to be specifically related to stroke

Rabbit Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) Interaktionspartner

  1. Gene expression profiling performed on tissues obtained from pulmonary sarcoidosis patients identified MMP12 as a potential pathogenic mediator of lung damage and/or remodeling and may serve as a marker for this disease.

MMP12 Antigen-Profil

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Genbezeichner und Symbole assoziert mit MMP12

  • matrix metallopeptidase 12 (MMP12) Antikörper
  • matrix metallopeptidase 12 (Mmp12) Antikörper
  • AV378681 Antikörper
  • HME Antikörper
  • ME Antikörper
  • MME Antikörper
  • Mmel Antikörper
  • MMP-12 Antikörper
  • MMP12 Antikörper

Bezeichner auf Proteinebene für MMP12

matrix metallopeptidase 12 (macrophage elastase) , matrix metalloproteinase 12 , MME , MMP-12 , macrophage elastase , macrophage metalloelastase , macrophage-metalloelastase , matrix metalloproteinase-12 , matrix metalloproteinase 12 (macrophage elastase) , macrophage metalloelastase MMP-12

GENE ID SPEZIES
451512 Pan troglodytes
17381 Mus musculus
117033 Rattus norvegicus
4321 Homo sapiens
100009559 Oryctolagus cuniculus
611789 Canis lupus familiaris
526981 Bos taurus
Ausgewählte Anbieter für anti-MMP12 (MMP12) Antikörper
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