anti-LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2) Antikörper

LATS2 encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. Zusätzlich bieten wir Ihnen und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LATS2 50523 Q7TSJ6
LATS2 305922  
LATS2 26524 Q9NRM7
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Top anti-LATS2 Antikörper auf antikoerper-online.de

Showing 10 out of 91 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using LATS2 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using LATS2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with LATS2 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. The anti-LATS2 Pab is used in Western blot to detect LATS2 in NIH/3T3 cell lysate. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IP, PLA, WB Detection of Human LATS2 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 mcg for WB, 1 mg for IP, 1/4 of IP loaded/lane) from HeLa cells. Antibodies: ABIN152335 used at 0.4 mcg/ml (A) and 1 mcg/ml (B) for WB and at 3 mcg/mg lysate for IP. LATS2 was also immunoprecipitated by another LATS2 antibody, which is an affinity purified antibody to a downstream epitope from LATS2. Detection: Chemiluminescence with an exposure time of 30 seconds (A and B). Proximity Ligation Assay: LATS2 Antibody [ABIN152335] - Secondary-conjugate Duolink In Situ PLA in Hela cells. goat anti-human CHK1 (ABIN152335) and rabbit anti-human LATS2 (ABIN152335). Image merged from DAPI (2ms), FITC/Green (25ms) and TRITC/Orange (250ms) exposures, 40X magnification. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-LATS2 Pab (ABIN391034) is used in Western blot to detect LATS2 in NIH/3T3 cell lysate. Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with LATS2 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Maus Kaninchen Unkonjugiert WB Mouse Lats2 Antibody (C-term) (ABIN1881491) western blot analysis in mouse testis tissue lysates (35 µg/lane). This demonstrates the Mouse Lats2 antibody detected the Mouse Lats2 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse heart labeled with Rabbit Anti phospho-LATS2 (Ser83) Polyclonal Antibody, Unconjugated (ABIN753568) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-LATS2 (Ser83) Polyclonal Antibody, Unconjugated  at 1:300 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$317.90
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Formalin-fixed and paraffin embedded rat heart labeled with Anti LATS2 Polyclonal Antibody, Unconjugated (ABIN753553) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti-LATS2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Maus Unkonjugiert WB Western Blot: LATS2 Antibody (2D3) [NBP2-45612] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LATS2. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$447.56
Details
Maus Kaninchen Unkonjugiert IHC, WB   100 μL Anmelden zum Anzeigen 7 bis 8 Tage
$454.67
Details
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details

LATS2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-LATS2 Antikörper

  1. Human Polyclonal LATS2 Primary Antibody für IP, PLA - ABIN152335 : Kilili, Kyriakis et al.: Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 ... in The Journal of biological chemistry 2010 (PubMed)
    Show all 14 Pubmed References

  2. Mouse (Murine) Polyclonal LATS2 Primary Antibody für WB - ABIN1881491 : Oh, Lee, Kim, Kim, Oh, Hwang, Kong, Kwon, Lim: Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse. in Molecular and cellular biology 2009 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen LATS2 Interaktionspartner

Mouse (Murine) LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2) Interaktionspartner

  1. The findings reveal a novel signal upstream of PRC2, and provide insight into the crucial role of LATS2 in coordinating the epigenome through regulation of PRC2.

  2. Study demonstrates that, in 3 different murine syngeneic tumor models (B16, SCC7, and 4T1), loss of the Hippo pathway kinases LATS1 (zeige LATS1 Antikörper)/2 (large tumor suppressor (zeige LATS1 Antikörper) 1 and 2) in tumor cells inhibits tumor growth; data indicate a new paradigm for how tumor immunogenicity is regulated through the Hippo signaling pathway in tumor cells.

  3. mice harboring liver-specific Lats2 conditional knockout (Lats2-CKO) displayed constitutive SREBP activation and overexpressed SREBP target genes and developed spontaneous fatty liver disease

  4. protein and mRNA expression of the MST1 (zeige MST1 Antikörper) and LATS2 were decreased significantly as mouse age increased (p < 0.05), however, the mRNA expression of them increased significantly in 16 m compared with 5 m as well as the protein expression of LATS2.

  5. Lats2 is recruited to the p53 (zeige TP53 Antikörper) pathway to coordinate proper transcriptional reprogramming.

  6. Lats2 regulates the balance between proliferation and differentiation during adipose development.

  7. miR (zeige MLXIP Antikörper)-302a plays a critical role in mediating the effects of folate on cell proliferation and cell cycle-specific apoptosis by targeting Lats2 gene.

  8. KIBRA (zeige WWC1 Antikörper) associates with and activates Lats (large tumor suppressor (zeige LATS1 Antikörper)) 1 and 2 kinases by stimulating their phosphorylation on the hydrophobic motif

  9. Lats2 plays an essential mitotic role in coordinating accurate cytokinesis completion, governing the stabilization of other mitotic regulators

  10. Lats2 affects both growth and death of cardiac myocytes, but it primarily regulates the size of the heart and acts as an endogenous negative regulator of cardiac hypertrophy.

Human LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2) Interaktionspartner

  1. Upregulated long non-coding RNA AGAP2 (zeige AGAP2 Antikörper)-AS1 (zeige PTGDR Antikörper) represses LATS2 and KLF2 (zeige KLF2 Antikörper) expression through interacting with EZH2 (zeige EZH2 Antikörper) and LSD1 (zeige KDM1A Antikörper) in non-small-cell lung cancer cells.

  2. Low LATS2 expression is associated with Liver Cancer.

  3. The LATS2 is a prognostic biomarker and a tumour metastasis suppressor in hepatocellular carcinoma.

  4. The findings reveal a novel signal upstream of PRC2, and provide insight into the crucial role of LATS2 in coordinating the epigenome through regulation of PRC2.

  5. PVT1 recruits EZH2 (zeige EZH2 Antikörper) to the large tumor suppressor (zeige LATS1 Antikörper) kinase 2 (LATS2) promoter and represses LATS2 transcription.

  6. findings reveal a non-canonical (that is, YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper)-independent) effect of LATS (zeige LATS1 Antikörper) in the regulation of human breast cell fate

  7. LATS2 as the direct target of miR (zeige MLXIP Antikörper)-372 in prostate cancer cells.

  8. Data suggest that, at least using the commercial antibodies used in this study, immunohistochemical staining for NF2 (neurofibromin 2 (zeige NF2 Antikörper)), LATS2 (large tumor suppressor (zeige LATS1 Antikörper) kinase 2), and YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper) (nuclear translocation of complex of Yes-associated protein [YAP (zeige YAP1 Antikörper)] with transcriptional coactivator with PDZ-binding motif (zeige WWTR1 Antikörper) [TAZ (zeige TAZ Antikörper)]) is not helpful for differential diagnosis of mesothelioma versus a benign proliferation.

  9. overexpression of LATS2 resulted in mobility inhibition in non-small cell lung cancer cell lines A549 and H1299, and reduced protein level of matrix metalloproteinase-2 (MMP-2 (zeige MMP2 Antikörper)) and MMP-9 (zeige MMP9 Antikörper).

  10. LATS2 was found to have binding sites for miR (zeige MLXIP Antikörper)-135b in the 3'UTR (zeige UTS2R Antikörper) region and results demonstrated that LATS2 is a direct target of miR (zeige MLXIP Antikörper)-135b which regulates its expression in breast cancer cells.

Zebrafish LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2) Interaktionspartner

  1. Thus AMOT (zeige AMOT Antikörper) is a direct substrate of Lats1 (zeige LATS1 Antikörper)/2 mediating functions of the Hippo pathway in endothelial cell migration and angiogenesis.

  2. lats (zeige LATS1 Antikörper) genes show distinctly different expression profiles during gastrulation. lats1 (zeige LATS1 Antikörper) is almost ubiquitously expressed through development, and lats2 is more prominently expressed in the non-neural ectoderm region of zebrafish gastrula.

Pig (Porcine) LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2) Interaktionspartner

  1. The lats2 exhibit inverted expression to YAP1 (zeige YAP1 Antikörper), another member of the Hippo pathway which positively regulates cell growth and proliferation, during the differentiation of 3T3-L1 preadipocytes.

LATS2 Antigen-Profil

Protein Überblick

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Genbezeichner und Symbole assoziert mit LATS2

  • large tumor suppressor kinase 2 (LATS2) Antikörper
  • large tumor suppressor 2 (Lats2) Antikörper
  • large tumor suppressor kinase 2 (Lats2) Antikörper
  • large tumor suppressor kinase 2 (lats2) Antikörper
  • 4932411G09Rik Antikörper
  • AV277261 Antikörper
  • AW228608 Antikörper
  • KPM Antikörper
  • lats2 Antikörper

Bezeichner auf Proteinebene für LATS2

kinase phosphorylated during mitosis protein , large tumor suppressor homolog 2 , serine/threonine-protein kinase LATS2 , serine/threonine-protein kinase kpm , large tumor suppressor, homolog 2 , LATS (large tumor suppressor, Drosophila) homolog 2 , LATS, large tumor suppressor, homolog 2 , serine/threonine kinase KPM , warts-like kinase , large tumor suppressor 2-like protein

GENE ID SPEZIES
100050150 Equus caballus
50523 Mus musculus
305922 Rattus norvegicus
26524 Homo sapiens
508208 Bos taurus
567674 Danio rerio
418949 Gallus gallus
477343 Canis lupus familiaris
100415907 Sus scrofa
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