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ENG encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. Zusätzlich bieten wir Ihnen Endoglin Kits (58) und Endoglin Proteine (50) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 755 products:
Human Polyclonal ENG Primary Antibody für FACS, IF (cc) - ABIN707561
Zhao, Yin, Guo, Wang, Wang, Chen: Placental expression of VEGF is increased in pregnancies with hydatidiform mole: possible association with developing very early onset preeclampsia. in Early human development 2013
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Human Monoclonal ENG Primary Antibody für FACS - ABIN4896992
Narcisi, Cleary, Brama, Hoogduijn, Tüysüz, ten Berge, van Osch: Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. in Stem cell reports 2015
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Human Polyclonal ENG Primary Antibody für FACS, IF (p) - ABIN670401
Boopathy, Pendergrass, Che, Yoon, Davis: Oxidative stress-induced Notch1 signaling promotes cardiogenic gene expression in mesenchymal stem cells. in Stem cell research & therapy 2014
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Horse (Equine) Monoclonal ENG Primary Antibody für FACS - ABIN118831
Haruta, Seon: Distinct human leukemia-associated cell surface glycoprotein GP160 defined by monoclonal antibody SN6. in Proceedings of the National Academy of Sciences of the United States of America 1986
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Mouse (Murine) Monoclonal ENG Primary Antibody für FACS - ABIN4896370
Madhu, Li, Dighe, Balian, Cui et al.: BMP-non-responsive Sca1+ CD73+ CD44+ mouse bone marrow derived osteoprogenitor cells respond to combination of VEGF and BMP-6 to display enhanced osteoblastic differentiation and ectopic bone ... in PLoS ONE 2014
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Human Polyclonal ENG Primary Antibody für EIA, WB - ABIN951149
Ríus, Smith, Almendro, Langa, Botella, Marchuk, Vary, Bernabéu: Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. in Blood 1999
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Guinea Pig Polyclonal ENG Primary Antibody für IHC, WB - ABIN2777735
Sanz-Rodriguez, Guerrero-Esteo, Botella, Banville, Vary, Bernabéu: Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins. in The Journal of biological chemistry 2004
Several germline variants in Hamartomatous Polyposis Syndrome genes were detected, among them three in ENG, two in BMPR1A (zeige BMPR1A Antikörper), one in PTEN (zeige PTEN Antikörper), and one in SMAD4 (zeige SMAD4 Antikörper). Although some of the detected variants have been reported previously none could be definitely pathogenic or likely pathogenic.
9q33.3q34.11 microdeletion including ENG gene identified in four patients with intellectual disability, epilepsy, nail (zeige CD244 Antikörper) dysplasia and bone malformations.
Endoglin has an important role in VSMC recruitment and blood vessel maturation during angiogenesis.
Soluble endoglin did not vary over the pregnancy course or between gestational hypertension, preeclampsia, and control groups.
Serum and placental LXR-alpha (zeige NR1H3 Antikörper) and endoglin levels were significantly higher in patients with preeclampsia than those in control group (P<0.05, each).
Our findings suggest a stronger chondrogenic potential of CD105(+) SMSCs in comparison to that of CD105(-) SMSCs and that CD105 enhances chondrogenesis of SMSCs by regulating TGF-beta (zeige TGFB1 Antikörper)/Smad2 (zeige SMAD2 Antikörper) signaling pathway, but not Smad1 (zeige GARS Antikörper)/5. Our study provides a better understanding of CD105 with respect to chondrogenic differentiation.
The novel ENG c.-58G/A substitution in the Endoglin promoter co-segregates with Hereditary hemorrhagic telangiectasia symptoms in a family and appears to affect the transcriptional regulation of the gene, resulting in reduced Endoglin expression.
sEng treatment resulted in an activation of NF-kappaB (zeige NFKB1 Antikörper), IL-6 (zeige IL6 Antikörper), suggesting activation of pro-inflammatory phenotype in endothelial cells.
In adolescents with type 1 diabetes mellitus (T1DM), soluble endoglin concentrations might increase in parallel to the deterioration in endothelial function before subclinical structural vascular alterations.
Akt (zeige AKT1 Antikörper) level was reduced in preeclamptic placentas relative to preterm control. Inhibition of PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) resulted in significantly elevated soluble endoglin release from endothelial cells, had no effect on MMP14 (zeige MMP14 Antikörper) mRNA expression but resulted in significantly reduced TIMP3 (zeige TIMP3 Antikörper). In contrast inhibiting PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) in placental explants or primary trophoblast did not change soluble endoglin release.
Endoglin controls blood vessel diameter through endothelial cell shape changes in response to haemodynamic cues.
Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 (zeige KDR Antikörper) signalling.
Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes
the TGFbeta1 (zeige TGFB1 Antikörper) coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overload
Endothelial cell-specific endoglin expression in islets of Langerhans is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size.
Study provides evidence that the expression of endoglin is required for the establishment of uterine receptivity and the decidualization process, which mediate embryo adhesion or the attachment reaction.
The changes in CD90 (zeige THY1 Antikörper) and CD105 expression in the testis and ovary of mice are reported.
the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patients.
These results demonstrate a requirement for endoglin in descendants of Pax3 (zeige PAX3 Antikörper)-expressing vascular cell precursors.
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
endoglin (Osler-Rendu-Weber syndrome 1)
, CD105 antigen
, cell surface MJ7/18 antigen
, transmembrane glycoprotein