anti-Embryonic Ectoderm Development (EED) Antikörper

EED encodes a member of the Polycomb-group (PcG) family. Zusätzlich bieten wir Ihnen Embryonic Ectoderm Development Kits (24) und Embryonic Ectoderm Development Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EED 8726 O75530
EED 13626 Q921E6
EED 293104  
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Top anti-Embryonic Ectoderm Development Antikörper auf antikoerper-online.de

Showing 10 out of 86 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IF, WB <b>WB Suggested Anti-EED Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:2500<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-EED <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.500 <br /> Positive Control: OVCAR-3 cell lysate <br /> EED is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-EED Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate Host: Rabbit <br /> Target Name: EED <br /> Sample Tissue: HepG2Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide <br />Primary Antibody Concentration: 4.0 µg/mL Peptide Concentration:..0 µg/mL Lysate Quantity:.41 µg/laneGel Concentration: 12 % 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged EED is 0.1 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert EIA, IF, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Western Blot: EED Antibody [NBP1-33417] - Sample (30 ug of whole cell lysate) A: A431 B: H1299 10% SDS PAGE; antibody diluted at 1:1000. Immunohistochemistry-Paraffin: EED Antibody [NBP1-33417] - Paraffin-embedded SAS Xenograft, using antibody at 1:100 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details

EED Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Embryonic Ectoderm Development Antikörper

  1. Cow (Bovine) Polyclonal EED Primary Antibody für IF, WB - ABIN2776407 : Rakotobe, Violot, Hong, Gouet, Boulanger: Mapping of immunogenic and protein-interacting regions at the surface of the seven-bladed beta-propeller domain of the HIV-1 cellular interactor EED. in Virology journal 2008 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal EED Primary Antibody für ELISA, WB - ABIN522175 : Martin, Popov, Aguilo, OLoghlen, Raguz, Snijders, Dharmalingam, Li, Thymiakou, Carroll, Zeisig, So, Peters, Episkopou, Walsh, Gil: Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK?a regulation. in The EMBO journal 2013 (PubMed)

Weitere Antikörper gegen Embryonic Ectoderm Development Interaktionspartner

Human Embryonic Ectoderm Development (EED) Interaktionspartner

  1. These findings support that Weaver (zeige KCNJ6 Antikörper) syndrome is a disorder with locus heterogeneity and can be due to pathogenic variants in either EZH2 (zeige EZH2 Antikörper) or EED. This case highlights the utility of exome sequencing as a clinical diagnostic tool for novel gene discovery as well as the importance of re-examination of exome data as new information about gene-disease associations becomes available.

  2. we have found two unrelated families of different ethnicities, with a similar rare phenotype, both associated with de novo mutations in this member of the PRC2 complex, we are confident that EED is indeed a novel overgrowth gene.

  3. Mutations of SUZ12 and EED are reported to have tumor suppressive functions. (Review)

  4. These results suggest that the SNPs of the EED gene might not be associated with susceptibility to CRC (zeige CALR Antikörper).

  5. An integral role for EED as an epigenetic exchange factor coordinating the activities of PRC1 (zeige PRC1 Antikörper) and 2, is reported.

  6. Data show that overall enhancer of zeste 2 (EZH2), embryonic ectoderm development (EED) and suppressor of zeste 12 homolog (SUZ12) expression in the colorectal cancer (CRC) tissues was significantly increased than in the non-cancerous tissue.

  7. EED, a component of Polycomb (zeige CBX2 Antikörper) repressive complex-2 (PRC2) that catalyzes methylation of lysine 27 of histone H3 (zeige HIST3H3 Antikörper) (H3K27), was involved in epithelial-mesenchymal transition (EMT (zeige ITK Antikörper)) of cancer cells induced by Transforming Growth Factor-beta (TGF-beta).

  8. Polycomb repressive complex 2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.

  9. EZH2 (zeige EZH2 Antikörper)-EED is necessary and sufficient for binding to the lncRNA HOTAIR.

  10. Although inactivating mutations in PRC2-encoding genes EZH2 (zeige EZH2 Antikörper), EED, and SUZ12 are present in T-cell acute lymphoblastic leukemia and in myeloid malignancies, gain-of-function mutations in EZH2 (zeige EZH2 Antikörper) are frequently observed in B-cell lymphoma.

Mouse (Murine) Embryonic Ectoderm Development (EED) Interaktionspartner

  1. Deletion of Eed but not Ezh2 (zeige EZH2 Antikörper) from embryonic urothelial progenitors caused premature differentiation of Krt5 (zeige KRT5 Antikörper)+ basal cells and ectopic expression of squamous cell markers.

  2. in the skin epithelium, EED, Suz12, and Ezh1 (zeige EZH1 Antikörper)/2 function largely as subunits of the PRC2 complex and have roles in skin development

  3. EED is required for proper erythropoiesis and for formation of hematopoietic progenitor and stem cells, but is dispensable for endothelial lineage commitment and early vascular patterning

  4. Genetic inactivation of Ezh2 (zeige EZH2 Antikörper) or Eed cooperates with NRASQ61K in leukemogenesis.

  5. EED affects the lymphoid versus myeloid decision processes within the lymphomyeloid lineage

  6. Inactivation of Eed impedes MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper)-mediated leukemogenesis through Cdkn2a (zeige CDKN2A Antikörper)-dependent and Cdkn2a (zeige CDKN2A Antikörper)-independent mechanisms in a murine model.

  7. Data suggest that Eed (embryonic ectoderm development) is necessary to silence the pluripotency network during differentiation.

  8. An integral role for EED as an epigenetic exchange factor coordinating the activities of PRC1 (zeige PRC1 Antikörper) and 2, is reported.

  9. a microRNA encoded by the imprinted Dlk1 (zeige DLK1 Antikörper)-Dio3 (zeige DIO3 Antikörper) region of mouse chromosome 12, miR (zeige MLXIP Antikörper)-323-3p, targets Eed (embryonic ectoderm development) mRNA.

  10. Ectopic gain of EED along with depletion of KDM6B (zeige Kdm6b Antikörper) in preimplantation mouse embryos abrogates CDX2 (zeige CDX2 Antikörper) and GATA3 (zeige GATA3 Antikörper) gene expression in the nascent trophoectoderm lineage.

Embryonic Ectoderm Development (EED) Antigen-Profil

Protein Überblick

This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit EED

  • embryonic ectoderm development (eed) Antikörper
  • embryonic ectoderm development (EED) Antikörper
  • embryonic ectoderm development S homeolog (eed.S) Antikörper
  • microRNA 6755 (MIR6755) Antikörper
  • embryonic ectoderm development (Eed) Antikörper
  • embryonic ectoderm development L homeolog (eed.L) Antikörper
  • eed Antikörper
  • ENSMUSG00000039373 Antikörper
  • HEED Antikörper
  • l(7)5Rn Antikörper
  • l7Rn5 Antikörper
  • lusk Antikörper
  • psXEED Antikörper
  • WAIT1 Antikörper
  • Xeed Antikörper
  • Xeed-A Antikörper
  • Xeed-B Antikörper
  • zgc:112509 Antikörper

Bezeichner auf Proteinebene für EED

polycomb protein eed , embryonic ectoderm development , WD protein associating with integrin cytoplasmic tails 1 , polycomb protein EED , embryonic ectoderm development protein variant 1 , polycomb protein eed-B , embryonic ectoderm development protein , lethal, Chr 7, Rinchik 5 , polycomb protein eed-A

GENE ID SPEZIES
550079 Xenopus (Silurana) tropicalis
703866 Macaca mulatta
100601094 Nomascus leucogenys
8726 Homo sapiens
550463 Danio rerio
398420 Xenopus laevis
426381 Gallus gallus
404183 Bos taurus
13626 Mus musculus
293104 Rattus norvegicus
100344036 Oryctolagus cuniculus
100728793 Cavia porcellus
476779 Canis lupus familiaris
101113712 Ovis aries
734571 Xenopus laevis
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