EED Antikörper (AA 1-300)

Produktnummer ABIN6139942

Produktdetails anti-EED Antikörper

Target: EED (Embryonic Ectoderm Development (EED))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EED Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Sequenz: MSEREVSTAP AGTDMPAAKK QKLSSDENSN PDLSGDENDD AVSIESGTNT ERPDTPTNTP NAPGRKSWGK GKWKSKKCKY SFKCVNSLKE DHNQPLFGVQ FNWHSKEGDP LVFATVGSNR VTLYECHSQG EIRLLQSYVD ADADENFYTC AWTYDSNTSH PLLAVAGSRG IIRIINPITM QCIKHYVGHG NAINELKFHP RDPNLLLSVS KDHALRLWNI QTDTLVAIFG GVEGHRDEVL SADYDLLGEK IMSCGMDHSL KLWRINSKRM MNAIKESYDY NPNKTNRPFI SQKIHFPDFS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EED (NP_694536.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-EED Antikörper (ABIN6139942)

Tang, Guo, Zhu, Huang, Liu, Cai, Yu, Wang: "Metformin inhibits ovarian cancer via decreasing H3K27 trimethylation." in: International journal of oncology, Vol. 52, Issue 6, pp. 1899-1911, (2018) (PubMed).

Details zu EED

Target: EED (Embryonic Ectoderm Development (EED))

Andere Bezeichnung: EED (EED Produkte)

Synonyme: Xeed antikoerper, heed antikoerper, wait1 antikoerper, EED antikoerper, HEED antikoerper, WAIT1 antikoerper, zgc:112509 antikoerper, Xeed-B antikoerper, eed antikoerper, psXEED antikoerper, ENSMUSG00000039373 antikoerper, l(7)5Rn antikoerper, l7Rn5 antikoerper, lusk antikoerper, Xeed-A antikoerper, embryonic ectoderm development antikoerper, embryonic ectoderm development S homeolog antikoerper, microRNA 6755 antikoerper, embryonic ectoderm development L homeolog antikoerper, eed antikoerper, EED antikoerper, eed.S antikoerper, MIR6755 antikoerper, Eed antikoerper, eed.L antikoerper

Hintergrund: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Two transcript variants encoding distinct isoforms have been identified for this gene.,EED,HEED,WAIT1,Epigenetics & Nuclear Signaling,Chromatin Remodeling,EED

Molekulargewicht: 45 kDa/50 kDa/53 kDa

Gen-ID: 8726

UniProt: O75530