anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Antikörper

CYP2D6 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Proteine (16) und Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Kits (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYP2D6 171522 Q64680
CYP2D6 1565 P10635
CYP2D6    
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Top anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Antikörper auf antikoerper-online.de

Showing 10 out of 132 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-CYP2D6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-CYP2D6 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: OVCAR-3 cell lysate <br /> CYP2D6 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-CYP2D6 <br /> Antibody Titration: 2.5 µg/mL <br /> Positive Control: Human Liver 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert WB Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A), NIH3T3 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB CYP2D6 Antibody (N-term) (ABIN658441) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the CYP2D6 antibody detected the CYP2D6 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
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Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 8 bis 11 Tage
340,48 €
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Ratte Kaninchen Unkonjugiert IHC (p), WB Anti-Cytochrome P450 2D6 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Kidney Tissue Lysate Lane 3: Rat Brain Tissue Lysate 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
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CYP2D6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Antikörper

  1. Human Polyclonal CYP2D6 Primary Antibody für IHC (p), WB - ABIN658441 : Gao, Zhang, Cui, Akinyi: Comparison of Paeoniflorin and Albiflorin on Human CYP3A4 and CYP2D6. in Evidence-based complementary and alternative medicine : eCAM 2015 (PubMed)

Weitere Antikörper gegen Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 Interaktionspartner

Human Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Interaktionspartner

  1. A total of 72 single nucleotide polymorphisms were identified. CYP2D6*1, *2, *4, *5, *10,*41, and duplication of the gene were found in the Orang Asli, whereby CYP2D6*2 and *41 alleles are reported for the first time in the Malaysian population

  2. Data suggest that expression of CYP2D6 in hepatocytes is repressed by MIRN370 (hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-370-3p); MIRN370 represses expression of CYP2D6 even under the influence of CYP2D6 inducer (the glucocorticoid dexamethasone); the mechanism appears to involve the facilitation of CYP2D6 mRNA degradation. (CYP2D6 = cytochrome P450 (zeige CYP Antikörper) family 2 subfamily D (zeige CYP Antikörper) member 6; MIRN370 = microRNA 370)

  3. Report predicted and measured CYP2D6 phenotype in a diverse South African population.

  4. No association between cytochrome P450 (zeige CYP Antikörper) CYP2D6 ultra-rapid metabolizer status and attempted suicide was observed in bivariate

  5. Studied frequency of ADRB1 (zeige ADRB1 Antikörper) Arginine389Glycine (Arg389Gly) and Cytochrome p450 2D6*10 (Cyp2D6*10) polymorphism in cases of heart failure-reduced ejection fraction (HFREF), and to evaluate the influence of the polymorphisms in response to beta-blocker (BB) therapy; found a statistically significant association was observed with CC genotype and Glisin-Glisin (GG) genotype.

  6. Variant genotypes of CYP2D6 are associated with an increased risk of esophageal squamous cell carcinoma in Kashmir, India.

  7. genetic variation in CYP2D6 is a key predictor for the response to tamoxifen in patients with breast cancer

  8. These results indicated that most of the allelic variants of CYP2D6 studied here, exhibited significantly decreased enzymatic activities towards methadone N-demethylation.

  9. Evaluation of CYP2D6 ultrarapid metabolism should take into account activity of the multiplied alleles to avoid potential misclassification.

  10. Of 830 patients with sickle cell disease, 621 (75%) had a CYP2D6 genotype result; 7.1% were ultra-rapid or possible ultra-rapid metabolizers, and 1.4% were poor metabolizers.

Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Antigen-Profil

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CYP2D6

  • cytochrome 2D6 (CYP2D6) Antikörper
  • cytochrome P450 2D6 (CYP2D6) Antikörper
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) Antikörper
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) Antikörper
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6) Antikörper
  • cytochrome P450, family 2, subfamily d, polypeptide 4 (Cyp2d4) Antikörper
  • cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D14) Antikörper
  • CPD6 Antikörper
  • CYP2D Antikörper
  • cyp2d2 Antikörper
  • Cyp2d4v1 Antikörper
  • Cyp2d4v2 Antikörper
  • CYP2D6 Antikörper
  • cyp2d6-a Antikörper
  • CYP2D7AP Antikörper
  • CYP2D7BP Antikörper
  • CYP2D7P2 Antikörper
  • CYP2D8P2 Antikörper
  • Cyp2d18 Antikörper
  • Cyp2d22 Antikörper
  • CYP2D42 Antikörper
  • CYP2DL1 Antikörper
  • CYPIID6 Antikörper
  • MGC64445 Antikörper
  • P450-DB1 Antikörper
  • P450C2D Antikörper
  • P450DB1 Antikörper

Bezeichner auf Proteinebene für CYP2D6

cytochrome P450 2D6 , cytochrome P450 CYP2D42 , cytochrome P450, family 2, subfamily D, polypeptide 6 , CYPIID18 , CYPIID4 , Cytochrome P450, subfamily IID4 , P450 2D-29/2D-35 , P450-CMF3 , P450-DB4 , cytochrome P450 2D-29 , cytochrome P450 2D-35 , cytochrome P450 2D4 , cytochrome P450 2d18 , cytochrome P450, family 2, subfamily d, polypeptide 22 , cytochrome P450, subfamily 2D, polypeptide 6 , cytochrome P450, subfamily IID, polypeptide 6 , cytochrome P450-CMF3 , cytochrome P450-DB4 , debrisoquine 4-hydroxylase , cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2 , cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2 , cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6 , cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1 , cytochrome P450-DB1 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , CYPIID14 , cytochrome P450 2D14 , CYPIID6

GENE ID SPEZIES
100500743 Felis catus
100568286 Ovis aries
678691 Macaca mulatta
379479 Xenopus laevis
446878 Xenopus laevis
548436 Xenopus (Silurana) tropicalis
171522 Rattus norvegicus
1565 Homo sapiens
282211 Bos taurus
470228 Pan troglodytes
Ausgewählte Anbieter für anti-Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6) Antikörper
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