anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) Antikörper

BUB1 encodes a kinase involved in spindle checkpoint function. Zusätzlich bieten wir Ihnen BUB1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BUB1 699 O43683
BUB1 296137  
BUB1 12235 O08901
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Top anti-BUB1 Antikörper auf antikoerper-online.de

Showing 10 out of 141 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using BUB1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Maus Maus Unkonjugiert ICC, FACS, IF, IHC (p), WB 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
$402.29
Details
Human Kaninchen Unkonjugiert FACS, WB BUB1A Antibody (N-term) (ABIN651630) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). BUB1A Antibody (N-term) (ABIN651630) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB Observed bind size: 122KD Anti-Bub1 Picoband antibody,  All lanes: Anti BUB1  at 0.5ug/ml WB: Recombinant Human BUB1 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma BUB1A Antibody (F1058) (ABIN392626) western blot analysis in T47D cell line lysates (35 µg/lane).This demonstrates the BUB1A antibody detected the BUB1A protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert IF, IP, WB   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$566.50
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert ICC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$466.62
Details
Human Kaninchen Unkonjugiert IHC (p), WB Human Small Intestine (formalin-fixed, paraffin-embedded) stained with BUB1 antibody ABIN293131 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

BUB1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-BUB1 Antikörper

  1. Human Polyclonal BUB1 Primary Antibody für ICC, ELISA - ABIN1001946 : Williams, Roberts, Gjoerup: Bub1: escapades in a cellular world. in Cell cycle (Georgetown, Tex.) 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal BUB1 Primary Antibody für ICC, ELISA - ABIN1001947 : Meraldi, Sorger: A dual role for Bub1 in the spindle checkpoint and chromosome congression. in The EMBO journal 2005 (PubMed)
    Show all 4 Pubmed References

  3. Mouse (Murine) Monoclonal BUB1 Primary Antibody für ICC, FACS - ABIN108553 : Liu, Hittle, Jablonski, Campbell, Yoda, Yen: Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. in Nature cell biology 2003 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Monoclonal BUB1 Primary Antibody für ICC, FACS - ABIN108554 : Qi, Tang, Yu: Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. in Molecular biology of the cell 2006 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal BUB1 Primary Antibody für IF, IP - ABIN2477744 : Vlasveld, Rankin, Hekman, Rodenhuis, Beijnen, Hilton, Dubbelman, Vyth-Dreese, Melief: A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects. in British journal of cancer 1992 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal BUB1 Primary Antibody für ICC, IF - ABIN2668285 : Liu, Rattner, Jablonski, Yen: Mapping the assembly pathways that specify formation of the trilaminar kinetochore plates in human cells. in The Journal of cell biology 2006 (PubMed)

  7. Human Polyclonal BUB1 Primary Antibody für IHC, IHC (p) - ABIN4993905 : Aggarwal, Kruczynski, Frankfurter, Correia, Lobert: Murine leukemia P388 vinorelbine-resistant cell lines are sensitive to vinflunine. in Investigational new drugs 2008 (PubMed)

Weitere Antikörper gegen BUB1 Interaktionspartner

Human Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) Interaktionspartner

  1. Chromosomal rearrangement resulting in BUB1 haploinsufficiency identified in a patient with polycystic liver disease. BUB1 may imply germline causes of genetic instability in PLD (zeige PLD Antikörper).

  2. Results report that BubR1 (zeige BUB1B Antikörper) and RepoMan bind directly to PP2A (zeige PPP2R4 Antikörper)-B56 using an LSPIxE short linear motif (SLiM), where phosphorylation of the Ser (zeige SIGLEC1 Antikörper) residue enhances binding. RepoMan and BubR1 (zeige BUB1B Antikörper) bind B56 using both hydrophobic and electrostatic interactions.

  3. Inhibition of Bub1 kinase impaired chromosome arm resolution but exerted only minor effects on mitotic progression or spindle assembly checkpoint function.

  4. Study shows that BUB1beta (zeige BUB1B Antikörper) and PDZ binding kinase (zeige PBK Antikörper) are up-regulated in breast cancer tumors and their expression is associated with improved overall survival (OS) in basal-like tumors but worse OS in luminal and untreated patients.

  5. Bub1 may be associated with cancer stem cell potential.

  6. Both Bub1 and BubR1 (zeige BUB1B Antikörper) bind stably to Bub3 (zeige BUB3 Antikörper) that is required for kinetochore localization of the proteins

  7. Bub1-Plk1 (zeige PLK1 Antikörper)-mediated phosphorylation of Cdc20 (zeige CDC20 Antikörper) constitutes an anaphase-promoting complex or cyclosome-inhibitory mechanism that is parallel, but not redundant, to mitotic checkpoint (zeige BUB3 Antikörper) complex formation.

  8. Data show that mitotic checkpoint (zeige BUB3 Antikörper) kinase (zeige ATR Antikörper) Bub1 is an active kinase regulated by intra-molecular phosphorylation at the P+1 loop.

  9. human BUB1 does not associate stably with the MAD2 (zeige MAD2L1 Antikörper) activator MAD1 (zeige MXD1 Antikörper) (also known as MAD1L1 (zeige MAD1L1 Antikörper)) and, although required for accelerating the loading of MAD1 (zeige MXD1 Antikörper) onto kinetochores, BUB1 is dispensable for the maintenance of steady-state levels of MAD1 (zeige MXD1 Antikörper) there

  10. MAD2L1 (zeige MAD2L1 Antikörper) and BUB1 may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

Mouse (Murine) Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) Interaktionspartner

  1. Bub1 coordinates checkpoint signalling by distinct domains for RZZ and BubR1 (zeige BUB1B Antikörper) recruitment and localizes antagonistic checkpoint activities.

  2. It was shown that that Bub1 kinase activity integrates attachment error correction and mitotic checkpoint signaling by controlling the localization and activity of Aurora B kinase through phosphorylation of histone H2A at threonine 121.

  3. Results establish that Bub1 has oncogenic properties and suggest that Aurora B (zeige AURKC Antikörper) is a critical target through which overexpressed Bub1 drives aneuploidization and tumorigenesis.

  4. It seems that Sgo1 (zeige SGOL1 Antikörper) sets up the centromeric protection mechanism in G2, but that its Bub1-dependent localisation to centromeres during mitosis is not required to maintain cohesion.

  5. mutations of Bub1 and BubR1 (zeige BUB1B Antikörper) found in Brca2 (zeige BRCA2 Antikörper)- mutant mice indeed are responsible for the chromosome instability in Brca2 (zeige BRCA2 Antikörper)-mutated tumors

  6. Our data suggest that Bub1 is a critical spindle checkpoint protein that regulates accurate chromosome alignment and homolog disjunction in mammalian oocyte meiosis.

  7. Bub1 is important for mediating cell death when chromosomes missegregate.

  8. Bub1 is essential for proper chromosome segregation, a defect that can lead to severe phenotypes, including perinatal lethality and a predisposition to cancer.

  9. Data show that the anaphase-promoting complex is activated in an exponential fashion after germinal vesicle breakdown in oocytes and that this process is advanced by 5 hr in oocytes lacking Bub1.

  10. Bub1 dysfunction is linked to inherited aneuploidy in female germ cells and may contribute to the maternal age-related increase in aneuploidy and pregnancy loss.

BUB1 Antigen-Profil

Protein Überblick

This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.

Genbezeichner und Symbole assoziert mit BUB1

  • BUB1 mitotic checkpoint serine/threonine kinase (BUB1) Antikörper
  • BUB1 mitotic checkpoint serine/threonine kinase (bub1) Antikörper
  • BUB1 mitotic checkpoint serine/threonine kinase (Bub1) Antikörper
  • BUB1, mitotic checkpoint serine/threonine kinase (Bub1) Antikörper
  • AL022991 Antikörper
  • Bub1a Antikörper
  • BUB1L Antikörper
  • C80208 Antikörper
  • D2Xrf87 Antikörper
  • hBUB1 Antikörper
  • xbub1 Antikörper

Bezeichner auf Proteinebene für BUB1

BUB1 budding uninhibited by benzimidazoles 1 homolog , mitotic checkpoint serine/threonine-protein kinase BUB1 , budding uninhibited by benzimidazoles 1 , budding uninhibited by benzimidazoles 1 homolog , mitotic spindle checkpoint kinase , putative serine/threonine-protein kinase , mBUB1

GENE ID SPEZIES
100064049 Equus caballus
459484 Pan troglodytes
780291 Xenopus (Silurana) tropicalis
699 Homo sapiens
296137 Rattus norvegicus
12235 Mus musculus
100682599 Canis lupus familiaris
514777 Bos taurus
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