BUB1 Antikörper (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast)) (AA 1043-1073)

Details for Product anti-BUB1 Antibody No. ABIN392626, Anbieter: Anmelden zum Anzeigen
Antigen
  • bub1a
  • bub1l
  • hbub1
  • xbub1
  • BUB1A
  • BUB1L
  • hBUB1
  • AL022991
  • Bub1a
  • C80208
  • D2Xrf87
  • BUB1 mitotic checkpoint serine/threonine kinase
  • BUB1, mitotic checkpoint serine/threonine kinase
  • BUB1
  • bub1
  • Bub1
Epitop
AA 1043-1073, C-Term
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12
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8
4
4
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3
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2
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2
1
1
Reaktivität
Human
158
51
34
1
Wirt
Kaninchen
107
51
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser BUB1 Antikörper ist unkonjugiert
4
4
4
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2
2
2
1
1
1
1
1
1
1
1
1
1
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1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
120
80
48
42
34
18
17
13
13
3
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This BUB1 (BUB1a) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1043-1073 AA from the C-terminal region of human BUB1 (BUB1a).
Klon RB03123-03124
Isotyp Ig Fraction
Spezifität This BUB1 (BUB1a) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1051~1080 amino acids from the C-terminal region of human BUB1A.
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Andere Bezeichnung BUB1 (BUB1a) (BUB1 Antibody Abstract)
Hintergrund This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Synonyms: Mitotic checkpoint serine/threonine-protein kinase BUB1, hBub1, BUB1A
Molekulargewicht 122375 DA
Gen-ID 699
UniProt O43683
Applikations-hinweise WB = 1:1000, IHC (p) = 1:50-100
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1043-1073), (C-Term) antibody (ABIN392626) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1043-1073), (C-Term) antibody (ABIN392626) BUB1A Antibody (F1058) (ABIN392626) western blot analysis in T47D cell line lysates (...
Allgemeine Veröffentlichungen Shichiri, Yoshinaga, Hisatomi, Sugihara, Hirata: "Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival." in: Cancer research, Vol. 62, Issue 1, pp. 13-7, 2002 (PubMed).

Cayrol, Cougoule, Wright: "The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1." in: Biochemical and biophysical research communications, Vol. 298, Issue 5, pp. 720-30, 2002 (PubMed).

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