BUB1 Antikörper (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast)) (AA 1043-1073)

Details for Product anti-BUB1 Antibody No. ABIN392626, Anbieter: Anmelden zum Anzeigen
Antigen
  • bub1a
  • bub1l
  • hbub1
  • xbub1
  • BUB1A
  • BUB1L
  • hBUB1
  • AL022991
  • Bub1a
  • C80208
  • D2Xrf87
  • BUB1 mitotic checkpoint serine/threonine kinase
  • BUB1, mitotic checkpoint serine/threonine kinase
  • BUB1
  • bub1
  • Bub1
Epitop
AA 1043-1073, C-Term
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Reaktivität
Human
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1
Wirt
Kaninchen
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Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser BUB1 Antikörper ist unkonjugiert
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Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This BUB1 (BUB1a) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1043-1073 AA from the C-terminal region of human BUB1 (BUB1a).
Klon RB03123-03124
Isotyp Ig Fraction
Spezifität This BUB1 (BUB1a) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1051~1080 amino acids from the C-terminal region of human BUB1A.
Reinigung This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Plasmids, Primers & others Plasmide, Primers & weitere BUB1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung BUB1 (BUB1a) (BUB1 Antibody Abstract)
Hintergrund This gene encodes a kinase involved in spindle checkpoint function. The kinase functions in part by phosphorylating a member of the miotic checkpoint complex and activating the spindle checkpoint. Mutations in this gene have been associated with aneuploidy and several forms of cancer.
Synonyms: Mitotic checkpoint serine/threonine-protein kinase BUB1, hBub1, BUB1A
Molekulargewicht 122375 DA
Gen-ID 699
UniProt O43683
Applikations-hinweise WB = 1:1000, IHC (p) = 1:50-100
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1043-1073), (C-Term) antibody (ABIN392626) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1) (AA 1043-1073), (C-Term) antibody (ABIN392626) BUB1A Antibody (F1058) (ABIN392626) western blot analysis in T47D cell line lysates (...
Allgemeine Veröffentlichungen Shichiri, Yoshinaga, Hisatomi, Sugihara, Hirata: "Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival." in: Cancer research, Vol. 62, Issue 1, pp. 13-7, 2002 (PubMed).

Cayrol, Cougoule, Wright: "The beta2-adaptin clathrin adaptor interacts with the mitotic checkpoint kinase BubR1." in: Biochemical and biophysical research communications, Vol. 298, Issue 5, pp. 720-30, 2002 (PubMed).

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