anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Antikörper

The protein encoded by AGAP2 belongs to the centaurin gamma-like family. Zusätzlich bieten wir Ihnen ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
AGAP2 116986 Q99490
AGAP2 216439 Q3UHD9
AGAP2 65218 Q8CGU4
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Top anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Antikörper auf antikoerper-online.de

Showing 10 out of 103 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-CENTG1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: THP-1 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert EIA, WB <span>CENTG1 Antibody (C-term) western blot analysis in mouse brain tissue lysates (35µg/lane).This demonstrates the CENTG1 antibody detected the CENTG1 protein (arrow).</span> 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
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Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
391,60 €
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 15 Tage
425,76 €
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Human Kaninchen Unkonjugiert WB CENTG1 Antibody (C-term) (ABIN654901) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the CENTG1 antibody detected the CENTG1 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: AGAP2 Antibody [NBP1-51941] - NBP1-51941 (0.3ug/ml) staining of Human Amygdala lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
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Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
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Human Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using Protein A purified anti-AGAP2 antibody shows detection of AGAP2 recombinant protein in transfected HEK293 cell lysates. No specific band staining is noted in mock transfected cell lysates (empty vector). The membrane was probed with the primary antibody diluted to 1:10,000. 100 μg Anmelden zum Anzeigen 5 bis 7 Tage
412,76 €
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Human Ziege Unkonjugiert IHC (p), ELISA, WB Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
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AGAP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Antikörper

  1. Human Polyclonal AGAP2 Primary Antibody für IHC, ELISA - ABIN1002996 : Jackson, Kearns, Theibert: Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling. in Trends in biochemical sciences 2000 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal AGAP2 Primary Antibody für ELISA, WB - ABIN4278646 : Liu, Jang, Liu, Cheng, Peng, Yepes, Li, Matthews, Watts, Asano, Hara-Nishimura, Luo, Ye: Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase. in Molecular cell 2008 (PubMed)

Weitere Antikörper gegen ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 Interaktionspartner

Human ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Interaktionspartner

  1. these findings support that PIKE amplification or overexpression coordinately acts with CDK4 (zeige CDK4 Antikörper) to drive glioblastoma tumorigenesis.

  2. Studies showed that overexpression or mutation of PIKE has been observed in a variety of tumors, promoting cancer cell growth, transformation and invasion through AKT signaling or other signaling pathways, such as focal adhesion kinase. [review]

  3. Mutation of Fyn (zeige FYN Antikörper) phosphorylation sites on PIKE-A, depletion of Fyn (zeige FYN Antikörper), or pharmacological inhibition of Fyn (zeige FYN Antikörper) blunts the association between PIKE-A and AMPK (zeige PRKAA1 Antikörper), resulting in loss of its inhibitory effect on AMPK (zeige PRKAA1 Antikörper).

  4. expression of PLC-gamma1 (zeige PLCG1 Antikörper) and PIKE positively correlated with the tumor differentiation of oral squamous cell carcinoma.

  5. PIKE reduction rescued PI3K (zeige PIK3CA Antikörper)-dependent and -independent neuronal defects in fragile X (zeige FMR1 Antikörper) syndrome.

  6. In this review the CENTG1 gene is amplified in a variety of human cancers which lead to the enhancement of tumor invasion.

  7. AGAP2 plays a role in the signalling and recycling of beta2-adrenergic receptors.

  8. Fyn (zeige FYN Antikörper) regulates the activity of the adipogenic transcription factor signal transducer and activator of transcription 5a (STAT5a (zeige STAT5A Antikörper)) through enhancing its interaction with the GTPase (zeige RACGAP1 Antikörper) phosphoinositide 3-kinase enhancer A (PIKE-A).

  9. PIKE is highly expressed in human squamous cell carcinoma and has a critical role in EGF (zeige EGF Antikörper)-induced squamous cell carcinoma proliferation.

  10. The presence of heterogeneous missense mutations of GGAP2 in prostate cancer was associated with aggressive clinical behavior.

Mouse (Murine) ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Interaktionspartner

  1. Depletion of PIKE-A in C2C12 myotubes diminished the inhibitory activities of TNF-alpha (zeige TNF Antikörper) on mitochondrial respiration and lipid oxidation, whereas PIKE-A overexpression exacerbated these cellular responses.

  2. PIKE plays pivotal roles to advance oligodendroglia development and myelinogenesis through Akt (zeige AKT1 Antikörper)/mTOR (zeige FRAP1 Antikörper) activation.

  3. Results demonstrate that the integrity of PIKE signaling is essential for protecting the neurons from excitotoxicity-stimulated damage both in vitro and in vivo.

  4. Fyn (zeige FYN Antikörper) regulates the activity of the adipogenic transcription factor signal transducer and activator of transcription 5a (STAT5a (zeige STAT5A Antikörper)) through enhancing its interaction with the GTPase (zeige RACGAP1 Antikörper) phosphoinositide 3-kinase enhancer A (PIKE-A).

  5. PIKE is a critical factor in controlling synaptic AMPA (zeige GRIA3 Antikörper) receptor insertion.

  6. data established the critical role of PIKE in regulating neuronal survival and development by substantiating the PI3K/Akt (zeige AKT1 Antikörper) pathway.

  7. PIKE-A is required for prolactin (zeige PRL Antikörper)-mediated STAT5a (zeige STAT5A Antikörper) activation in mammary gland development.

  8. PIKE knockout mice show augmented lipid oxidation, which is accompanied by enhanced AMPK (zeige PRKAA1 Antikörper) phosphorylation in muscle and adipose tissue and is implicated in obesity and diabetes development.

  9. PIKE-L acts as a downstream survival effector for netrin-1 (zeige NTN1 Antikörper) through UNC5B (zeige UNC5B Antikörper) in the nervous system

ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit AGAP2

  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2) Antikörper
  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (agap2) Antikörper
  • ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (Agap2) Antikörper
  • Centg1 Antikörper
  • GGAP2 Antikörper
  • mKIAA0167 Antikörper
  • Pike Antikörper
  • zgc:153779 Antikörper

Bezeichner auf Proteinebene für AGAP2

arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 , Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2 , GTP-binding and GTPase activating protein 2 , centaurin, gamma 1 , cnt-g1 , phosphatidylinositol 3-kinase enhancer , phosphatidylinositol-3-kinase enhancer , phosphoinositide 3-kinase enhancer , AGAP-2 , PIKE , centaurin-gamma-1 , nuclear GTPase PIKE

GENE ID SPEZIES
504833 Bos taurus
565109 Danio rerio
116986 Homo sapiens
216439 Mus musculus
65218 Rattus norvegicus
100050853 Equus caballus
481130 Canis lupus familiaris
Ausgewählte Anbieter für anti-ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2) Antikörper
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