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AGAP2 Produkte

(ArfGAP with GTPase Domain, Ankyrin Repeat and PH Domain 2 (AGAP2))

Kategorien

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

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Ausgewählte AGAP2 Kategorien

AGAP2 Antikörper

High quality antibodies with extensive validation data.

AGAP2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene AGAP2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN570975
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (3)
  • (2)
Kat. Nr. ABIN541229
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN654901
Menge 400 μL
Datenblatt Datenblatt

Empfohlene AGAP2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6223198
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AGAP2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1344548
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3088375
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3135049
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AGAP2 Produkten

Liu, Jang, Liu, Cheng, Peng, Yepes, Li, Matthews, Watts, Asano, Hara-Nishimura, Luo, Ye: "Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase." in: Molecular cell, Vol. 29, Issue 6, pp. 665-78, (2008) (PubMed).

Ahn, Rong, Kroll, Van Meir, Snyder, Ye: "PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion." in: The Journal of biological chemistry, Vol. 279, Issue 16, pp. 16441-51, (2004) (PubMed).

Hatziioannou, Perez-Caballero, Yang, Cowan, Bieniasz: "Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 29, pp. 10774-9, (2004) (PubMed).

Stremlau, Owens, Perron, Kiessling, Autissier, Sodroski: "The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys." in: Nature, Vol. 427, Issue 6977, pp. 848-53, (2004) (PubMed).

Xu, Yang, Moitra, Hashimoto, Rallabhandi, Kaul, Meroni, Jensen, Weissman, DArpa: "BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta." in: Experimental cell research, Vol. 288, Issue 1, pp. 84-93, (2003) (PubMed).

Rong, Ahn, Huang, Nagata, Kalman, Kapp, Tu, Worley, Snyder, Ye: "PI3 kinase enhancer-Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis." in: Nature neuroscience, Vol. 6, Issue 11, pp. 1153-61, (2003) (PubMed).

Ye, Hurt, Wu, Fang, Luo, Hong, Blackshaw, Ferris, Snyder: "Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N." in: Cell, Vol. 103, Issue 6, pp. 919-30, (2001) (PubMed).

Jackson, Kearns, Theibert: "Cytohesins and centaurins: mediators of PI 3-kinase-regulated Arf signaling." in: Trends in biochemical sciences, Vol. 25, Issue 10, pp. 489-95, (2000) (PubMed).

Synonyme und alternative Namen zu AGAP2

ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (AGAP2), ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (agap2), ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 (Agap2), CENTG1, Centg1, GGAP2, mKIAA0167, PIKE, Pike, zgc:153779

Bezeichner auf Proteinebene für AGAP2

  • arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2
  • Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2
  • GTP-binding and GTPase activating protein 2
  • centaurin, gamma 1
  • cnt-g1
  • phosphatidylinositol 3-kinase enhancer
  • phosphatidylinositol-3-kinase enhancer
  • phosphoinositide 3-kinase enhancer
  • AGAP-2
  • PIKE
  • centaurin-gamma-1
  • nuclear GTPase PIKE
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