anti-Aconitase 2, Mitochondrial (ACO2) Antikörper

The protein encoded by ACO2 belongs to the aconitase/IPM isomerase family. Zusätzlich bieten wir Ihnen ACO2 Kits (29) und ACO2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ACO2 50 Q99798
ACO2 11429 Q99KI0
ACO2 79250 Q9ER34
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Top anti-ACO2 Antikörper auf antikoerper-online.de

Showing 10 out of 112 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-ACO2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ACO2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Western Blot: Aconitase 2 Antibody [NBP1-32781] - Sample (30 ug of whole cell lysate) A: 293T B: A431 7.5% SDS PAGE, antibody diluted at 1:10000. Immunocytochemistry/Immunofluorescence: Aconitase 2 Antibody [NBP1-32781] - Analysis of methanol-fixed HeLa, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-ACO2 Pab (ABIN388648) in mouse heart(left) and 293 (right) tissue lysates (35 µg/lane). ACO2(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Perfused isolated rat heart whole tissue lysate was lysed with either A) 50 mM Tris-HCl, 150 mM NaCl, 1 mM EDTA, 1% NP-40, 0.1% SDS, 0.5% Na-deoxycholate, 1 mM Na3VO4, 20 mM NaF, 1 mM PMSF, 5 v/v % protease inhibitor cocktail or B) T-PER Tissue Protein Extraction Reagent [# 785101. Pierce], containing 1mM Na3VO4, 20 mM NaF, 5 v/v % protease inhibitor cocktail (Sigma). PVDF membrane was incubated in primary Ab [rabbit polyclonal antibody against ACO2 (Center) (ABIN388648). Solution: 1:1000 diluted in 5% NFM TBS-T 0,05 for overnight (15 hrs) at 4 °. Data courtesy of Boglarka Laczy M.D., Division of Cardiovascular Disease, Dept. of Medicine, University of Alabama at Birmingham. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: Aconitase 2 Antibody [NBP1-90264] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells).Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells).Lane 3: PC12 cell lysate (Pheochromocytoma of rat adrenal medulla) Immunocytochemistry/Immunofluorescence: Aconitase 2 Antibody [NBP1-90264] - Staining of human cell line U-2 OS shows positivity in mitochondria. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of ACO2 (arrow) using rabbit polyclonal ACO2 Antibody (Center) (ABIN391809).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ACO2 gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ACO2 antibody (Center) (ABIN391809), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Ziege Unkonjugiert IHC, ELISA, WB (0.01µg/ml) staining of Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
Details
Human Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: Aconitase 2 Antibody [NBP1-52014] - (3.8ug/ml) staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Western Blot: Aconitase 2 Antibody [NBP1-52014] - (0.01ug/ml) staining of Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details

ACO2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)
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Am meisten referenzierte anti-ACO2 Antikörper

  1. Human Polyclonal ACO2 Primary Antibody für IHC (p), WB - ABIN388648 : OConnell, Gannon, Doran, Ohlendieck: Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle. in International journal of molecular medicine 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal ACO2 Primary Antibody für EIA, WB - ABIN357262 : Geurts van Kessel, Westerveld, de Groot, Meera Khan, Hagemeijer: Regional localization of the genes coding for human ACO2, ARSA, and NAGA on chromosome 22. in Cytogenetics and cell genetics 1981 (PubMed)
    Show all 8 Pubmed References

  3. Cow (Bovine) Polyclonal ACO2 Primary Antibody für WB - ABIN2786627 : Yu, Costello, Feng, Franklin: Characterization of the mitochondrial aconitase promoter and the identification of transcription factor binding. in The Prostate 2006 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal ACO2 Primary Antibody für ICC, IF - ABIN4277666 : Cantu, Fulton, Drechsel, Patel: Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂. in Journal of neurochemistry 2011 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal ACO2 Primary Antibody für IHC (p), WB - ABIN391809 : Dey, Guha, Alam, Goyal, Bindu, Pal, Maity, Mitra, Bandyopadhyay: Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis. in Free radical biology & medicine 2009 (PubMed)

  6. Human Monoclonal ACO2 Primary Antibody für ELISA - ABIN513071 : Lin, Brownsey, MacLeod: Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. in Cellular and molecular life sciences : CMLS 2009 (PubMed)

  7. Cow (Bovine) Polyclonal ACO2 Primary Antibody für IHC, WB - ABIN2786628 : Scheving, Wittig, Heide, Albuquerque, Steger, Brandt, Tegeder: Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve. in Journal of proteomics 2012 (PubMed)

  8. Human Polyclonal ACO2 Primary Antibody für ELISA, IHC - ABIN4277664 : Bota, Davies: Lon protease preferentially degrades oxidized mitochondrial aconitase by an ATP-stimulated mechanism. in Nature cell biology 2002 (PubMed)

  9. Human Polyclonal ACO2 Primary Antibody für ICC, IF - ABIN442737 : Tammineni, Anugula, Mohammed, Anjaneyulu, Larner, Sepuri: The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain. in The Journal of biological chemistry 2013 (PubMed)

Weitere Antikörper gegen ACO2 Interaktionspartner

Arabidopsis thaliana Aconitase 2, Mitochondrial (ACO2) Interaktionspartner

  1. The identification of ACO1 (zeige ACO1 Antikörper), ACO2, and ACO3 in A. thaliana is reported, and it was demonstrated that, in plants, the cytosolic ACOs are not converted into iron regulatory proteins.

Human Aconitase 2, Mitochondrial (ACO2) Interaktionspartner

  1. Results suggest that ACO2 activity is reduced in peripheral lymphocytes of subjects with Alzheimer's disease and mild cognitive impairment and correlates with antioxidant protection

  2. Our study shows that autosomal recessive ACO2 mutations can cause either isolated or syndromic optic neuropathy.

  3. immunofluorescence staining localized ACO2 to the human sperm mid-piece. By immunoblotting, we demonstrated that the level of ACO2 protein in asthenozoospermic samples was significantly decreased compared with that in normal fertile men

  4. Ogg1 (zeige OGG1 Antikörper) chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.

  5. Hypoxia upregulates the gene expression of mitochondrial aconitase in prostate carcinoma cells

  6. Gastric cancer patients with lower ACO2 expression have a shorter survival time than those with higher ACO2 expression.

  7. Homozygosity mapping followed by whole-exome sequencing disclosed a Ser112Arg mutation in ACO2.

  8. these results suggest that p53 downregulation of mACON gene expression in human prostate carcinoma cells may not occur through the putative consensus p53 response elements found within the mACON promoter.

  9. Lon (zeige LONP1 Antikörper) protease selectively recognizes and degrades the oxidized, hydrophobic form of aconitase (zeige ACO1 Antikörper) after mild oxidative modification, but that severe oxidation results in aconitase (zeige ACO1 Antikörper) aggregation, which makes it a poor substrate for Lon (zeige LONP1 Antikörper).

  10. ACO2 is often deleted in colorectal cancer (zeige DCC Antikörper) but is unlikely to be the true target of the deletions

Mouse (Murine) Aconitase 2, Mitochondrial (ACO2) Interaktionspartner

  1. Activation of mitochondrial aconitase is acetylation-dependent.

  2. Ogg1 (zeige OGG1 Antikörper) chaperoning of Aco-2 in preventing oxidant-mediated mtDNA damage and apoptosis may afford an innovative target for the molecular events underlying oxidant-induced toxicity.

  3. IRP-1 (zeige ACO1 Antikörper),-2 are indispensable for regulation of mammalian iron homeostasis at the post-implantation stage of murine embryonic development

  4. aconitase activity can be regulated by at least two mechanisms: oxidation/reduction and phosphorylation/dephosphorylation

Pig (Porcine) Aconitase 2, Mitochondrial (ACO2) Interaktionspartner

  1. study examined the sites and mechanisms of aconitase inactivation by peroxynitrite (ONOO-), a strong oxidant and nitrating agent readily formed from superoxide anion and nitric oxide generated by mitochondria

ACO2 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.

Genbezeichner und Symbole assoziert mit ACO2

  • aconitase 2, mitochondrial (ACO2) Antikörper
  • aconitase 2, mitochondrial (aco2) Antikörper
  • aconitate hydratase, mitochondrial (Bm1_07420) Antikörper
  • aconitase, mitochondrial (aco2) Antikörper
  • mitochondrial aconitate hydratase (ach1) Antikörper
  • aconitase 2 (ACO2) Antikörper
  • aconitase 2, mitochondrial (LOC100352714) Antikörper
  • aconitase 2, mitochondrial (Aco2) Antikörper
  • Protein ACO-2 (aco-2) Antikörper
  • Aco-2 Antikörper
  • Aco3 Antikörper
  • aconitase 2 Antikörper
  • ACONM Antikörper
  • cb1017 Antikörper
  • D10Wsu183e Antikörper
  • DDBDRAFT_0206187 Antikörper
  • DDBDRAFT_0230168 Antikörper
  • DDB_0206187 Antikörper
  • DDB_0230168 Antikörper
  • F10M23.310 Antikörper
  • F10M23_310 Antikörper
  • ICRD Antikörper
  • wu:fa10e03 Antikörper
  • wu:fb69g04 Antikörper
  • wu:fc20c11 Antikörper

Bezeichner auf Proteinebene für ACO2

aconitate hydratase, mitochondrial , mitochondrial aconitate hydratase , aconitase 2, mitochondrial , aconitate hydratase, mitochondrial-like , citrate hydro-lyase , mitochondrial aconitase (nuclear aco2 gene) , heart aconitase

GENE ID SPEZIES
374009 Gallus gallus
444692 Xenopus laevis
6096411 Brugia malayi
8621690 Dictyostelium discoideum AX4
9617127 Volvox carteri f. nagariensis
100444223 Pongo abelii
496933 Xenopus (Silurana) tropicalis
707441 Macaca mulatta
828805 Arabidopsis thaliana
100352714 Oryctolagus cuniculus
100389367 Callithrix jacchus
100568244 Anolis carolinensis
100598337 Nomascus leucogenys
50 Homo sapiens
11429 Mus musculus
79250 Rattus norvegicus
396999 Sus scrofa
280976 Bos taurus
474487 Canis lupus familiaris
322670 Danio rerio
176121 Caenorhabditis elegans
Ausgewählte Anbieter für anti-ACO2 (ACO2) Antikörper
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