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ACO2 Antikörper (AA 438-467)

ACO2 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB9338 unconjugated
Produktnummer ABIN388648
  • Target Alle ACO2 Antikörper anzeigen
    ACO2 (Aconitase 2, Mitochondrial (ACO2))
    Bindungsspezifität
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 438-467
    Reaktivität
    • 58
    • 35
    • 34
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 52
    • 4
    • 2
    Kaninchen
    Klonalität
    • 45
    • 13
    Polyklonal
    Konjugat
    • 33
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser ACO2 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 25
    • 19
    • 7
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, M, Pig
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ACO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 amino acids from the Central region of human ACO2.
    Klon
    RB9338
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ACO2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Ruiz, Bégou, Launay, Ranea-Robles, Bianchi, López-Erauskin, Morató, Guilera, Petit, Vaurs-Barriere, Guéret-Gonthier, Bonnet-Dupeyron, Fourcade, Auwerx, Boespflug-Tanguy, Pujol: "Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease." in: Brain pathology (Zurich, Switzerland), (2017) (PubMed).

    Navarro, Botella, Metzendorf, Lind, Schneuwly: "Mitoferrin modulates iron toxicity in a Drosophila model of Friedreich?s ataxia." in: Free radical biology & medicine, Vol. 85, pp. 71-82, (2015) (PubMed).

    Fernandes, Uytterhoeven, Kuenen, Wang, Slabbaert, Swerts, Kasprowicz, Aerts, Verstreken: "Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration." in: The Journal of cell biology, Vol. 207, Issue 4, pp. 453-62, (2014) (PubMed).

    Maity, Bindu, Dey, Goyal, Alam, Pal, Mitra, Bandyopadhyay et al.: "Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: a novel ..." in: The Journal of biological chemistry, Vol. 284, Issue 5, pp. 3058-68, (2009) (PubMed).

    OConnell, Gannon, Doran, Ohlendieck: "Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle." in: International journal of molecular medicine, Vol. 20, Issue 2, pp. 145-53, (2007) (PubMed).

  • Target
    ACO2 (Aconitase 2, Mitochondrial (ACO2))
    Andere Bezeichnung
    ACO2 (ACO2 Produkte)
    Synonyme
    DDBDRAFT_0206187 antikoerper, DDBDRAFT_0230168 antikoerper, DDB_0206187 antikoerper, DDB_0230168 antikoerper, aconitase 2 antikoerper, F10M23.310 antikoerper, F10M23_310 antikoerper, ACONM antikoerper, ICRD antikoerper, Aco-2 antikoerper, Aco3 antikoerper, D10Wsu183e antikoerper, cb1017 antikoerper, wu:fa10e03 antikoerper, wu:fb69g04 antikoerper, wu:fc20c11 antikoerper, aconitase 2 antikoerper, aconitase 2 S homeolog antikoerper, aconitate hydratase, mitochondrial antikoerper, aconitase, mitochondrial antikoerper, mitochondrial aconitate hydratase antikoerper, aconitase 2, mitochondrial antikoerper, Probable aconitate hydratase, mitochondrial antikoerper, ACO2 antikoerper, aco2.S antikoerper, Bm1_07420 antikoerper, aco2 antikoerper, ach1 antikoerper, Aco2 antikoerper, aco-2 antikoerper
    Hintergrund
    ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
    Molekulargewicht
    85425
    Gen-ID
    50
    NCBI Accession
    NP_001089
    UniProt
    Q99798
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