ACO2 Antikörper (N-Term)

Produktnummer ABIN2786627

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-ACO2 Antikörper wird verwendet zum Nachweis von ACO2 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Saccharomyces cerevisiae, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für ACO2 Antikörper (N-Term) (ABIN2786627)

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Saccharomyces cerevisiae, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACO2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ACO2 Antibody - N-terminal region

Sequenz: LQFISSGLSK VAVPSTIHCD HLIEAQVGGE KDLRRAKDIN QEVYNFLATA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ACO2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACO2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56301-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACO2 Antikörper (ABIN2786627)

Schauer, Freund, Prenni, Curthoys: "Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 305, Issue 5, pp. F628-40, (2013) (PubMed).

Freund, Prenni, Curthoys: "Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 304, Issue 2, pp. F145-55, (2013) (PubMed).

Details zu ACO2

Target: ACO2 (Aconitase 2, Mitochondrial (ACO2))

Andere Bezeichnung: ACO2

Hintergrund:

Background Information: ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Aconitase 2, mitochondrial

Alternative Symbols: ICRD, OCA8, OPA9, ACONM, HEL-S-284

Protein Name: Aconitate hydratase, mitochondrial

Molekulargewicht: 82kDa

Gen-ID: 50

NCBI Accession: NP_001089

UniProt: Q99798