anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) Antikörper

The protein encoded by ABCG8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ABCG8 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCG8 64241 Q9H221
ABCG8 67470 Q9DBM0
ABCG8 155192 P58428
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Top anti-ABCG8 Antikörper auf antikoerper-online.de

Showing 10 out of 79 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: ABCG8 Antibody [ABIN438175] - Total protein from Mouse small intestine was separated on a 7.5% gel by SDS-PAGE and transferred to PVDF membrane. The membrane was then probed with anti-ABCG8 antibody at 2 ug/ml and detected with an anti-rabbit HRP conjugated secondary antibody using chemiluminescence. Immunocytochemistry/Immunofluorescence: ABCG8 Antibody [ABIN438175] - ABCG8 antibody was tested in HEK293 cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.2 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of ABCG8, using ABIN152887. Samples: mouse liver microsomes from G5/G8 knockout mice, wildtype human G5/G8, and transgenic human G5/G8. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$415.44
Details
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus Unkonjugiert ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry: ABCG8 Antibody (1B10A5) [NBP1-71706] - Immunohistochemical analysis of ABCG8 in mouse intestine using NBP1-71706. Western Blot: ABCG8 Antibody (1B10A5) [NBP1-71706] - Analysis of ABCG8 expression in ABCG8 lysate using NBP1-71706. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: ABCG8 Antibody [NBP1-83388] - Staining of human cell line U-251MG shows positivity in cytoplasm. Immunohistochemistry-Paraffin: ABCG8 Antibody [NBP1-83388] - Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse liver labeled with Anti-STSL/ABCG8 Polyclonal Antibody, Unconjugated (ABIN1387509) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Biotin WB   0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert ELISA, WB The ABCG8 Antibody is used in Western blot to detect ABCG8 in human fetal liver lysates. 0.1 mg Anmelden zum Anzeigen 2 bis 6 Tage
$327.00
Details
Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 7 bis 9 Tage
$793.83
Details

ABCG8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)


Am meisten referenzierte anti-ABCG8 Antikörper

  1. Human Polyclonal ABCG8 Primary Antibody für ICC, IF - ABIN152894 : Mathur, Watt, Field: Regulation of intestinal NPC1L1 expression by dietary fish oil and docosahexaenoic acid. in Journal of lipid research 2007 (PubMed)
    Show all 10 Pubmed References

  2. Human Monoclonal ABCG8 Primary Antibody für ICC, IF - ABIN4277252 : Graf, Yu, Li, Gerard, Tuma, Cohen, Hobbs: ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion. in The Journal of biological chemistry 2003 (PubMed)
    Show all 7 Pubmed References

  3. Human Polyclonal ABCG8 Primary Antibody für WB - ABIN152887 : Garcia, Wilund, Arca, Zuliani, Fellin, Maioli, Calandra, Bertolini, Cossu, Grishin, Barnes, Cohen, Hobbs: Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein. in Science (New York, N.Y.) 2001 (PubMed)
    Show all 8 Pubmed References

  4. Polyclonal ABCG8 Primary Antibody für WB - ABIN540800 : Remaley, Bark, Walts, Freeman, Shulenin, Annilo, Elgin, Rhodes, Joyce, Dean, Santamarina-Fojo, Brewer: Comparative genome analysis of potential regulatory elements in the ABCG5-ABCG8 gene cluster. in Biochemical and biophysical research communications 2002 (PubMed)
    Show all 5 Pubmed References

  5. Human Polyclonal ABCG8 Primary Antibody für WB - ABIN438154 : Maqdasy, El Hajjaji, Baptissart, Viennois, Oumeddour, Brugnon, Trousson, Tauveron, Volle, Lobaccaro, Baron: Identification of the Functions of Liver X Receptor-β in Sertoli Cells Using a Targeted Expression-Rescue Model. in Endocrinology 2015 (PubMed)

  6. Human Polyclonal ABCG8 Primary Antibody für ICC, IF - ABIN4277253 : Ahn, Jang, Jun, Lee, Shin: Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease. in Digestive diseases and sciences 2014 (PubMed)

Weitere Antikörper gegen ABCG8 Interaktionspartner

Human ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) Interaktionspartner

  1. ABCG8 genetic variants may have role in the development of cholelithiasis in patients with Gaucher disease type 1.

  2. Genetic polymorphism within the ABCG8 gene is a risk factor for diabetes.

  3. crystallization in lipid bilayers to determine the X-ray structure of human G5G8 in a nucleotide-free state at 3.9 A resolution, generating the first atomic model of an ABC (zeige ABCB6 Antikörper) sterol transporter

  4. A polymorphism of the sterol transporter ABCG8 has been associated with the prevalence of end-stage renal disease

  5. Mutation in ABCG8 is associated with sitosterolaemia.

  6. ATP-binding cassette (ABC (zeige ABCB6 Antikörper)) transporters G5 (ABCG5 (zeige ABCG5 Antikörper)) and G8 (ABCG8) form an obligate heterodimer that limits intestinal absorption and facilitates biliary secretion of cholesterol and phytosterols.

  7. ABCG5 (zeige ABCG5 Antikörper)/8 variants are associated with susceptibility to coronary heart disease.

  8. Sitosterolemia is caused by a genetic defect of sterolins (ABCG5 (zeige ABCG5 Antikörper)/ABCG8) mapped to the STSL (zeige ABCG5 Antikörper) locus. Polymorphic variations in STSL (zeige ABCG5 Antikörper) have been linked to lipid levels and gallstone disease

  9. HRD1 (zeige SYVN1 Antikörper) and RMA1 may therefore be negative regulators of disease-associated transporter ABCG5 (zeige ABCG5 Antikörper)/ABCG8.

  10. MI and gallstones, 2 seemingly unrelated diseases, are intrinsically linked via the function of the ABCG5 (zeige ABCG5 Antikörper)/8 cholesterol transporter.

Mouse (Murine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) Interaktionspartner

  1. ABCG5 (zeige ABCG5 Antikörper) and ABCG8 mRNA levels were significantly increased in cholesterol group and less increased in myriocin group, relative to that in normal group.

  2. The ABCG5 (zeige ABCG5 Antikörper)/G8-independent pathway plays an important role in regulating biliary cholesterol secretion, and gallstone formation, which works independently of the ABCG5 (zeige ABCG5 Antikörper)/G8 pathway.

  3. ABCG5 (zeige ABCG5 Antikörper)/G8 mediate mass biliary cholesterol secretion but not from a reverse cholesterol transport-relevant pool.

  4. AdGRP78 reduced expression of lipogenic genes and plasma triglycerides in the db/db (zeige LEPR Antikörper) strain. Both G5 and G8 protein levels increased as did total biliary cholesterol

  5. The data demonstrate that Abcg5 (zeige ABCG5 Antikörper)/Abcg8 deficiency reduces the uptake and secretion of both dietary triacylglycerols and cholesterol by the intestine, suggesting a novel role for the sterol transporter in the formation and secretion of chylomicrons.

  6. Sitosterolemia is caused by a genetic defect of sterolins (ABCG5 (zeige ABCG5 Antikörper)/ABCG8) mapped to the STSL locus. Polymorphic variations in STSL have been linked to lipid levels and gallstone disease

  7. The absence of an ABCG5 (zeige ABCG5 Antikörper)/ABCG8 expression.

  8. biliary cholesterol mass secretion under maximal bile salt-stimulated conditions is fully dependent on ABCG5 (zeige ABCG5 Antikörper)/G8

  9. This study is the first to report such toxic effects of phytosterol accumulation in ABCG5 (zeige ABCG5 Antikörper)/G8 knockout mice.

  10. handling of sterols by the intestine involves both G5G8 and ACAT2 but that an additional factor (possibly Niemann-Pick C1-like 1) may be key in determining absorption efficiency

Cow (Bovine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8) Interaktionspartner

  1. high expression levels of both ATP-binding cassette sub-family G member 5 (zeige ABCG5 Antikörper) and 8 (ABCG5 (zeige ABCG5 Antikörper) and ABCG8) were present in bovine liver and digestive tract samples, and in the mammary gland

ABCG8 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

Genbezeichner und Symbole assoziert mit ABCG8

  • ATP binding cassette subfamily G member 8 (ABCG8) Antikörper
  • ATP-binding cassette sub-family G member 8 (PTRG_02054) Antikörper
  • ABC transporter G family protein (abcG8) Antikörper
  • ATP-binding cassette, sub-family G (WHITE), member 8 (abcg8) Antikörper
  • ATP binding cassette subfamily G member 8 (Abcg8) Antikörper
  • 1300003C16Rik Antikörper
  • AI114946 Antikörper
  • DDBDRAFT_0167690 Antikörper
  • DDBDRAFT_0191232 Antikörper
  • DDB_0167690 Antikörper
  • DDB_0191232 Antikörper
  • GBD4 Antikörper
  • sterolin-2 Antikörper
  • STSL Antikörper
  • zgc:172358 Antikörper

Bezeichner auf Proteinebene für ABCG8

ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) , sterolin 2 , ATP-binding cassette sub-family G member 8 , sterolin-2 , ATP-binding cassette, sub-family G (WHITE), member 8 , ATP-binding cassette sub-family G member 8-like , ATP-binding cassette, subfamily G, member 8

GENE ID SPEZIES
100069071 Equus caballus
421402 Gallus gallus
470363 Pan troglodytes
6338845 Pyrenophora tritici-repentis Pt-1C-BFP
8619568 Dictyostelium discoideum AX4
100033372 Monodelphis domestica
100136850 Danio rerio
100350554 Oryctolagus cuniculus
100402530 Callithrix jacchus
100445033 Pongo abelii
100466630 Ailuropoda melanoleuca
100601594 Nomascus leucogenys
64241 Homo sapiens
67470 Mus musculus
474571 Canis lupus familiaris
100048963 Sus scrofa
508829 Bos taurus
155192 Rattus norvegicus
Ausgewählte Anbieter für anti-ABCG8 (ABCG8) Antikörper
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