Oncostatin M Protein (OSM)
-
- Target Alle Oncostatin M (OSM) Proteine anzeigen
- Oncostatin M (OSM)
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
-
Spezies
- Human
-
Quelle
- Escherichia coli (E. coli)
- Sequenz
- MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLG CVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRF LHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR TRPSRKGKRL MTRGQLPR
- Produktmerkmale
-
Purified recombinant Human Oncostatin M protein
Expression System: E.coli
Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ? 2 ng/mL, corresponding to a specific activity of ? 5 x 10^5 units/mg. - Reinheit
- > 98 % pure
- Endotoxin-Niveau
- < 0.1 ng per µg (1 EU/µg).
- Top Product
- Discover our top product OSM Protein
-
Oncostatin M (OSM) (AA 26-221) protein (His-Avi Tag)
OSM Spezies: Human Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) (AA 25-206) protein (His tag)OSM Spezies: Maus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Oncostatin M (OSM) protein (His-Avi Tag,Biotin)OSM Spezies: Human Wirt: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Oncostatin M (OSM) (AA 26-239) protein (His tag)OSM Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Oncostatin M (OSM) (AA 26-221) protein (His tag)OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Oncostatin M (OSM) (AA 26-234) protein (His tag)OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Oncostatin M (OSM) (AA 1-252) protein (GST tag)OSM Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Oncostatin M (OSM) protein (His tag)OSM Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Oncostatin M (OSM) (AA 26-252) proteinOSM Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Supplied as a lyophilized powder.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
-
- Target
- Oncostatin M (OSM)
- Andere Bezeichnung
- Oncostatin M (OSM Produkte)
- Hintergrund
-
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, OSH can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells.
Alternative Names: OSM protein - Molekulargewicht
- 26 kDa
- Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
-
