NGFB Protein

Produktnummer ABIN935676

Dieses Recombinant NGFB-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für NGFB Protein (ABIN935676)

Target: NGFB (Nerve Growth Factor beta (NGFB))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: > 98 % pure

Produktdetails

Sequenz: SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR

Produktmerkmale: Purified recombinant Human beta NGF protein
Expression System: E.coli
Bioactivity: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The ED50 is 1 x 10^6 units/mg.

Endotoxin-Niveau: < 0.1 ng per µg (1 EU/µg).

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in water to a concentration of 0.1 - 1.0 mg/mL.

Buffer: Supplied lyophilized with no additives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.

Antigendetails

Target: NGFB (Nerve Growth Factor beta (NGFB))

Andere Bezeichnung: beta NGF

Hintergrund: Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival.
Alternative Names: beta-NGF protein, Nerve Growth factor protein, NGF-beta protein

Molekulargewicht: 13.5 kDa

Pathways: NF-kappaB Signalweg, RTK Signalweg, Regulation of Cell Size