JAK2 Protein (AA 508-800)

Produktnummer ABIN8128528

Dieses Recombinant JAK2-Protein wird in Escherichia coli (E. coli) exprimiert.

Kurzübersicht für JAK2 Protein (AA 508-800) (ABIN8128528)

Target: JAK2 (Janus Kinase 2 (JAK2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Activity Assay (AcA), Cell Culture (CC)

Reinheit: > 90 %

Produktdetails

Proteineigenschaft: AA 508-800

Verwendungszweck: Active Janus Kinase 2 (JAK2)

Sequenz: Asn508-Ala800

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

STABILITY: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Isoelectric Point: 6.7

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 20 mM Tris, 150 mM NaCl (PH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Buffer: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01 % SKL, 5 % Trehalose and Proclin300.

Konservierungsmittel: Dithiothreitol (DTT), Other preservative, ProClin

Vorsichtsmaßnahmen: This product contains ProClin and Dithiothreitol (DTT): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Antigendetails

Target: JAK2 (Janus Kinase 2 (JAK2))

Andere Bezeichnung: Janus Kinase 2

Hintergrund: JTK10, Tyrosine-protein kinase JAK2

Molekulargewicht: 35kDa

UniProt: O60674

Pathways: JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response