IL-6 Protein
Kurzübersicht für IL-6 Protein (ABIN7937108)
Target
Alle IL-6 (IL6) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Verwendungszweck
- Recombinant Rat Interleukin-6
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Sequenz
- FPTSQVRRGD FTEDTTHNRP VYTTSQVGGL ITYVLREILE MRKELCNGNS DCMNSDDALS ENNLKLPEIQ RNDGCFQTGY NQEICLLKIC SGLLEFRFYL EFVKNNLQDN KKDKARVIQS NTETLVHIFK QEIKDSYKIV LPTPTSNALL MEKLESQKEW LRTKTIQLIL KALEEFLKVT MRSTRQT
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Sterilität
- 0.2 μm filtered
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Endotoxin-Niveau
- Less than 1 EU/ug of rRtIL-6 as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.01 ng/ml, corresponding to a specific activity of > 1.0 x108 IU/mg.
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Kommentare
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Approximately 21.7 kDa, a single, non-glycosylated polypeptide chain containing 187 amino acids
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Haltbarkeit
- 12 months
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Andere Bezeichnung
- Interleukin-6
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Molekulargewicht
- 21.7 kDa
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Gen-ID
- 24498
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UniProt
- P20607
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Pathways
- TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Target
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