SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag)

Produktnummer ABIN6992361

Dieses Recombinant SARS-CoV-2 Spike S1-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für SARS-CoV-2 Spike S1 Protein (P.1 - gamma) (His tag) (ABIN6992361)

Target: SARS-CoV-2 Spike S1

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Gamma

Quelle: HEK-293 Cells

Reinheit: >90 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: P.1 - gamma

Aufreinigungstag / Konjugat: Dieses SARS-CoV-2 Spike S1 Protein ist gelabelt mit His tag.

Verwendungszweck: SARS-CoV-2 S1 protein (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y), His Tag

Sequenz: AA 16-685

Produktmerkmale: SARS-CoV-2 S1 protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1). L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y mutations were identified in the SARS-CoV-2 variant (known as P.1 lineage) which emerged in Brazil.

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Antigendetails

Target: SARS-CoV-2 Spike S1

Andere Bezeichnung: SARS-CoV-2 S1 protein

Substanzklasse: Viral Protein

Hintergrund: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molekulargewicht: 76.9 kDa