SQSTM1 Protein (AA 1-356) (His tag)
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- Target Alle SQSTM1 Proteine anzeigen
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-356
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses SQSTM1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- SQSTM1, 1-356 aa, Human, His-tagged, Recombinant, E.coli
- Reinheit
- > 90 % by SDS-PAGE
- Top Product
- Discover our top product SQSTM1 Protein
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Sequestosome 1 (SQSTM1) (AA 108-237) protein (His-IF2DI Tag)
SQSTM1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Sequestosome 1 (SQSTM1) (AA 85-440) protein (His tag)SQSTM1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Sequestosome 1 (SQSTM1) (AA 1-440) protein (GST tag)SQSTM1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Sequestosome 1 (SQSTM1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SQSTM1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT.
- Lagerung
- 4 °C
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- Target
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Andere Bezeichnung
- SQSTM1 (SQSTM1 Produkte)
- Hintergrund
- SQSTM1 is an adapter protein which binds ubiquitin and regulates signaling cascades through ubiquitination. It may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1 and play a role in titin/TTN downstream signaling in muscle cells. This protein also may be involved in cell differentiation, apoptosis, immune response and regulation of K+ channels. Mutations in the ubiquitin-associated (UBA) domain of the sequestosome 1 protein commonly cause Paget’s disease since the UBA is necessary for aggregate sequestration and cell survival. Recombinant SQSTM1 protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: A170, OSIL, p60, p62, p62B, PDB3, ZIP3, Sequestosome 1 EBI 3 associated protein of 60 kDa, ZIP, ZIP 3, EBI3 associated protein of 60 kDa, EBIAP, MGC127197, ORCA.M530, OSF-6, Osi, Oxidative stress induced like, Paget disease of bone 3, PDB 3, Phosphotyrosine independent ligand for the Lck SH2 domain of 62 kDa, Phosphotyrosine independent ligand for the Lck SH2 domain p62, PKC-zeta-interacting protein, Protein kinase C-zeta-interacting protein, SQSTM 1, STAP, STONE14, Ubiquitin binding protein p62,. NCBI no.: NP_001135771
- Molekulargewicht
- 39.7 kDa (364aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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