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SQSTM1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SQSTM1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2712374
  • Target Alle SQSTM1 Proteine anzeigen
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 7
    • 2
    • 2
    • 1
    Human
    Quelle
    • 7
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses SQSTM1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human SQSTM1 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SQSTM1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Andere Bezeichnung
    Sqstm1 (SQSTM1 Produkte)
    Synonyme
    SQSTM1 Protein, sqstm1 Protein, MGC79491 Protein, A170 Protein, OSIL Protein, PDB3 Protein, ZIP3 Protein, p60 Protein, p62 Protein, p62B Protein, OSF-6 Protein, Osi Protein, STAP Protein, ZIP Protein, sb:cb621 Protein, zgc:85784 Protein, sequestosome 1 Protein, sequestosome 1 L homeolog Protein, SQSTM1 Protein, sqstm1 Protein, Sqstm1 Protein, sqstm1.L Protein
    Hintergrund
    This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
    Molekulargewicht
    47.5 kDa
    NCBI Accession
    NP_003891
    Pathways
    NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
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