IL-6 Protein (AA 30-212)
Kurzübersicht für IL-6 Protein (AA 30-212) (ABIN7676726)
Target
Alle IL-6 (IL6) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 30-212
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Sequenz
- MVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM
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Aufreinigung
- > 95% by SDS-PAGE
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Endotoxin-Niveau
- < 1 EU per 1ug of protein (determined by LAL method)
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Biological Activity Comment
- Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 1ng/ml.
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Interleukin 6 (IL6) (AA 30-212) protein (His tag,mFc Tag)
IL6 Spezies: Human Wirt: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. IA, ADA, AM, ScA
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 90 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 28-212) (Active) protein (His tag)IL6 Spezies: Cynomolgus Wirt: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Interleukin 6 (IL6) (AA 29-212) (Active) proteinIL6 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE analysis. Active
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Spezies: Maus Wirt: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 30-212) (Active) protein (His tag)IL6 Spezies: Human Wirt: HEK-293 Cells > 97 % AcA, CC Active
Interleukin 6 (IL6) (AA 30-212) (Active) proteinIL6 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Interleukin 6 (IL6) (AA 1-212) protein (GST tag)IL6 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 6 (IL6) (AA 25-211) (Active) protein (His tag)IL6 Spezies: Maus Wirt: Baculovirus infected Insect Cells Recombinant > 95 % SDS, AcA Active
Interleukin 6 (IL6) (AA 21-207) protein (His tag)IL6 Spezies: Hund Wirt: Baculovirus infected Insect Cells Recombinant > 95 % SDS
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Bioactivity Validated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4)
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- IL-6 (IL6) (Interleukin 6 (IL6))
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Andere Bezeichnung
- IL-6
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Hintergrund
- IL6, also known as interleukin 6. It is a cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. This protein plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. Recombinant human IL6 protein was expressed in E. coli and purified by using conventional chromatography techniques.
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Molekulargewicht
- 20.9 kDa (184aa)
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NCBI Accession
- NP_000591
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Pathways
- TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
Target
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