Prothrombin Protein (AA 328-622)
Kurzübersicht für Prothrombin Protein (AA 328-622) (ABIN5853681)
Target
Alle Prothrombin (F2) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 328-622
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Sequenz
- MTFGSGEADC GLRPLFEKKS LEDKTERELL ESYIDGRIVE GSDAEIGMSP WQVMLFRKSP QELLCGASLI SDRWVLTAAH CLLYPPWDKN FTENDLLVRI GKHSRTRYER NIEKISMLEK IYIHPRYNWR ENLDRDIALM KLKKPVAFSD YIHPVCLPDR ETAASLLQAG YKGRVTGWGN LKETWTANVG KGQPSVLQVV NLPIVERPVC KDSTRIRITD NMFCAGYKPD EGKRGDACEG DSGGPFVMKS PFNNRWYQMG IVSWGEGCDR DGKYGFYTHV FRLKKWIQKV IDQFGE
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Coagulation Factor II (thrombin) (F2) (Active) protein (His tag)
F2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
Coagulation Factor II (thrombin) (F2) (AA 1-622) protein (GST tag)F2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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Denatured
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.4M urea, 10 % glycerol.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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Andere Bezeichnung
- F2
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Hintergrund
- Coagulation factor II, also known as F2, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Recombinant human F2 protein was expressed in E.coli.
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Molekulargewicht
- 33.9kDa (296aa)
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NCBI Accession
- NP_000497
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UniProt
- P00734
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Pathways
- Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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