Prothrombin Protein
Kurzübersicht für Prothrombin Protein (ABIN934835)
Target
Alle Prothrombin (F2) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Produktmerkmale
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Purified native Human Prothrombin protein
Bioactivity: 9.7 units/mg protein - One unit of activity is equivalent to the Prothrombin activity in one milliliter of human normal plasma.
Protein Source: Human serum/plasma
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Coagulation Factor II (thrombin) (F2) (AA 1-622) protein (GST tag)
F2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
Coagulation Factor II (thrombin) (F2) (AA 328-622) protein (His tag)F2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 80 % SDS
Coagulation Factor II (thrombin) (F2) (Active) protein (His tag)F2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied as a liquid with 50 % Glycerol/H2 O (vol/vol).
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Vorsichtsmaßnahmen
- Donor samples were tested and found to be negative for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot and store at -20 °C.
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- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
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Andere Bezeichnung
- Prothrombin
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Hintergrund
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Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to gamma-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes.
Description: Human serum/plasma. -
Molekulargewicht
- 72 kDa
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Pathways
- Komplementsystem, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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