Bcl-2 Protein (AA 5-205, partial) (His tag)
Kurzübersicht für Bcl-2 Protein (AA 5-205, partial) (His tag) (ABIN5709125)
Target
Alle Bcl-2 (BCL2) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 5-205, partial
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Aufreinigungstag / Konjugat
- Dieses Bcl-2 Protein ist gelabelt mit His tag.
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Sequenz
- GRTGYDNREI VMKYIHYKLS QRGYEWDAGD ADAAPLGAAP TPGIFSFQPE SNPMPAVHRD MAARTSPLRP LVATAGPALS PVPPVVHLTL RRAGDDFSRR YRRDFAEMSS QLHLTPFTAR GRFATVVEEL FRDGVNWGRI VAFFEFGGVM CVESVNREMS PLVDNIALWM TEYLNRHLHT WIQDNGGWDA FVELYGPSMR P
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Aufreinigung
- SDS-PAGE
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B-Cell CLL/lymphoma 2 (BCL2) (AA 1-236) protein (His tag)
custom-made BCL2 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (His tag)custom-made BCL2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (GST tag)BCL2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 2 (BCL2) (AA 5-205) protein (His tag)BCL2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-211) protein (His-IF2DI Tag)BCL2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 140-239) protein (GST tag)BCL2 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-211) protein (His tag)BCL2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90% by SDS-PAGE SDS
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Lagerung
- -80 °C,4 °C,-20 °C
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Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Andere Bezeichnung
- BCL2
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Hintergrund
- Suppresses apoptosis in a variety of cell systs including factor-dependent lymphohatopoietic and neural cells. Regulates cell death by controlling the mitochondrial mbrane permeability. Appears to function in a feedback loop syst with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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Molekulargewicht
- 26.8 kDa
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UniProt
- P10417
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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