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MAPK14 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

MAPK14 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2725277
  • Target Alle MAPK14 Proteine anzeigen
    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 4
    Spezies
    • 11
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses MAPK14 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human MAP kinase p38 alpha / MAPK14 (transcript variant 4) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MAPK14 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
    Andere Bezeichnung
    Map Kinase p38 Alpha,mapk14 (MAPK14 Produkte)
    Synonyme
    CSBP Protein, CSBP1 Protein, CSBP2 Protein, CSPB1 Protein, EXIP Protein, Mxi2 Protein, PRKM14 Protein, PRKM15 Protein, RK Protein, SAPK2A Protein, p38 Protein, p38ALPHA Protein, CRK1 Protein, Csbp1 Protein, Csbp2 Protein, Exip Protein, Hog Protein, Prkm14 Protein, Prkm15 Protein, Sapk2A Protein, p38Hog Protein, p38alpha Protein, p38b Protein, zp38b Protein, MAPK14 Protein, 186F5S Protein, BG:DS00797.3 Protein, CG7393 Protein, D-p38 Protein, D-p38 MAPK Protein, D-p38b Protein, Dm p38b Protein, Dmel\\CG7393 Protein, Dmp38b Protein, Dp38 Protein, Dp38b Protein, ESTS:186F5S Protein, Mpk34C Protein, anon-sts23 Protein, dp38b Protein, p38 MAPK Protein, p38 beta Protein, p38B Protein, p38Kb Protein, p38beta Protein, Crk1 Protein, p38-alpha Protein, p38MAPK Protein, p38a Protein, csbp Protein, mapk14a Protein, mxi2 Protein, sapk2 Protein, sapk2a Protein, AP22.98 Protein, AP22_98 Protein, ATMPK14 Protein, mitogen-activated protein kinase 14 Protein, SAPK2a Protein, MAP kinase 14A Protein, MAP kinase p38a Protein, MAPK 14A Protein, fk28c03 Protein, hm:zeh1243 Protein, wu:fk28c03 Protein, zp38a Protein, P38C-CRK Protein, mitogen-activated protein kinase 14 Protein, mitogen activated protein kinase 14 Protein, mitogen-activated protein kinase 14b Protein, p38b MAP kinase Protein, mitogen-activated protein kinase 14 S homeolog Protein, mitogen-activated protein kinase 14a Protein, CRK proto-oncogene, adaptor protein Protein, MAPK14 Protein, Mapk14 Protein, mapk14b Protein, p38b Protein, mapk14.S Protein, MPK14 Protein, mapk14a Protein, CRK Protein
    Hintergrund
    The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
    Molekulargewicht
    35.3 kDa
    NCBI Accession
    NP_620583
    Pathways
    MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine
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