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Bcl-2 Protein (B-Cell CLL/lymphoma 2) (Myc-DYKDDDDK Tag)

BCL2 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715191
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle Bcl-2 (BCL2) Proteine anzeigen
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Protein-Typ
    Recombinant
    Spezies
    • 12
    • 4
    • 2
    • 2
    • 2
    Human
    Quelle
    • 16
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Bcl-2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Bcl-2 (transcript variant alpha) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Andere Bezeichnung
    Bcl-2 (BCL2 Produkte)
    Synonyme
    Bcl-2, PPP1R50, bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik, BCL-2, Bcl2, BCL2, apoptosis regulator, B cell leukemia/lymphoma 2, B-cell CLL/lymphoma 2a, B-cell CLL/lymphoma 2 protein, BCL2, Bcl2, bcl2a, BCL-2
    Hintergrund
    This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    26.1 kDa
    NCBI Accession
    NP_000624
    Pathways
    MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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