Bcl-2 Protein (B-Cell CLL/lymphoma 2) (Myc-DYKDDDDK Tag)
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- Target Alle Bcl-2 (BCL2) Proteine anzeigen
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses Bcl-2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human Bcl-2 (transcript variant alpha) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (GST tag)
BCL2 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-236) protein (rho-1D4 tag)Crystallography grade BCL2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (rho-1D4 tag)Crystallography grade BCL2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
B-Cell CLL/lymphoma 2 (BCL2) (AA 140-239) protein (GST tag)BCL2 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
B-Cell CLL/lymphoma 2 (BCL2) (AA 5-205), (partial) protein (His tag)BCL2 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Andere Bezeichnung
- Bcl-2 (BCL2 Produkte)
- Synonyme
- Bcl-2, PPP1R50, bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik, BCL-2, Bcl2, BCL2, apoptosis regulator, B cell leukemia/lymphoma 2, B-cell CLL/lymphoma 2a, B-cell CLL/lymphoma 2 protein, BCL2, Bcl2, bcl2a, BCL-2
- Hintergrund
- This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
- Molekulargewicht
- 26.1 kDa
- NCBI Accession
- NP_000624
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
